Q9P2G9: Kelch-like protein 8

General Information

Protein names	- Kelch-like protein 8
Gene names	KLHL8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9P2G9

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASDSMSSKQ ARNHITKGKR QQQHQQIKNR SSISDGDGED SFIFEANEAW KDFHGSLLRF
        70         80         90        100        110        120
YENGELCDVT LKVGSKLISC HKLVLACVIP YFRAMFLSEM AEAKQTLIEI RDFDGDAIED
       130        140        150        160        170        180
LVKFVYSSRL TLTVDNVQPL LYAACILQVE LVARACCEYM KLHFHPSNCL AVRAFAESHN
       190        200        210        220        230        240
RIDLMDMADQ YACDHFTEVV ECEDFVSVSP QHLHKLLSSS DLNIENEKQV YNAAIKWLLA
       250        260        270        280        290        300
NPQHHSKWLD ETLAQVRLPL LPVDFLMGVV AKEQIVKQNL KCRDLLDEAR NYHLHLSSRA
       310        320        330        340        350        360
VPDFEYSIRT TPRKHTAGVL FCVGGRGGSG DPFRSIECYS INKNSWFFGP EMNSRRRHVG
       370        380        390        400        410        420
VISVEGKVYA VGGHDGNEHL GSMEMFDPLT NKWMMKASMN TKRRGIALAS LGGPIYAIGG
       430        440        450        460        470        480
LDDNTCFNDV ERYDIESDQW STVAPMNTPR GGVGSVALVN HVYAVGGNDG MASLSSVERY
       490        500        510        520        530        540
DPHLDKWIEV KEMGQRRAGN GVSKLHGCLY VVGGFDDNSP LSSVERYDPR SNKWDYVAAL
       550        560        570        580        590        600
TTPRGGVGIA TVMGKIFAVG GHNGNAYLNT VEAFDPVLNR WELVGSVSHC RAGAGVAVCS
       610        620
CLTSQIRDVG HGSNNVVDCM

Isoforms

- Isoform 2 of Kelch-like protein 8

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9P2G9-1-unknown	MASDSM...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt79133
Q9P2G9-2-unknown	MASDSM...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9P2G9-2-Acetylation	ASDSMS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9P2G9-2-Acetylation	ASDSMS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9P2G9-2-Acetylation	ASDSMS...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9P2G9-2-Acetylation	ASDSMS...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110099
Q9P2G9-352-unknown	MNSRRR...	352		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439514
Q9P2G9-352-unknown	MNSRRR...	352		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt132438

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VVDCM	620	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...VVDCM	620	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt74751

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)