Q9P2N7: Kelch-like protein 13

General Information

Protein names	- Kelch-like protein 13 - BTB and kelch domain-containing protein 2
Gene names	KLHL13
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9P2N7

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Kelch-like protein 13 - Isoform 3 of Kelch-like protein 13 - Isoform 4 of Kelch-like protein 13 - Isoform 5 of Kelch-like protein 13

Sequence View

        10         20         30         40         50         60
MPLKWKTSSP AIWKFPVPVL KTSRSTPLSP AYISLVEEED QHMKLSLGGS EMGLSSHLQS
        70         80         90        100        110        120
SKAGPTRIFT SNTHSSVVLQ GFDQLRLEGL LCDVTLMPGD TDDAFPVHRV MMASASDYFK
       130        140        150        160        170        180
AMFTGGMKEQ DLMCIKLHGV SKVGLRKIID FIYTAKLSLN MDNLQDTLEA ASFLQILPVL
       190        200        210        220        230        240
DFCKVFLISG VTLDNCVEVG RIANTYNLTE VDKYVNSFVL KNFPALLSTG EFLKLPFERL
       250        260        270        280        290        300
AFVLSSNSLK HCTELELFKA TCRWLRLEEP RMDFAAKLMK NIRFPLMTPQ ELINYVQTVD
       310        320        330        340        350        360
FMRTDNTCVN LLLEASNYQM MPYMQPVMQS DRTAIRSDTT HLVTLGGVLR QQLVVSKELR
       370        380        390        400        410        420
MYDEKAHEWK SLAPMDAPRY QHGIAVIGNF LYVVGGQSNY DTKGKTAVDT VFRFDPRYNK
       430        440        450        460        470        480
WMQVASLNEK RTFFHLSALK GYLYAVGGRN AAGELPTVEC YNPRTNEWTY VAKMSEPHYG
       490        500        510        520        530        540
HAGTVYGGVM YISGGITHDT FQKELMCFDP DTDKWIQKAP MTTVRGLHCM CTVGERLYVI
       550        560        570        580        590        600
GGNHFRGTSD YDDVLSCEYY SPILDQWTPI AAMLRGQSDV GVAVFENKIY VVGGYSWNNR
       610        620        630        640        650
CMVEIVQKYD PDKDEWHKVF DLPESLGGIR ACTLTVFPPE ETTPSPSRES PLSAP         10         20         30         40         50         60
MPLKWKTSSP AIWKFPVPVL KTSRSTPLSP AYISLVEEED QHMKLSLGGS EMGLSSHLQS
        70         80         90        100        110        120
SKAGPTRIFT SNTHSSVVLQ GFDQLRLEGL LCDVTLMPGD TDDAFPVHRV MMASASDYFK
       130        140        150        160        170        180
AMFTGGMKEQ DLMCIKLHGV SKVGLRKIID FIYTAKLSLN MDNLQDTLEA ASFLQILPVL
       190        200        210        220        230        240
DFCKVFLISG VTLDNCVEVG RIANTYNLTE VDKYVNSFVL KNFPALLSTG EFLKLPFERL
       250        260        270        280        290        300
AFVLSSNSLK HCTELELFKA TCRWLRLEEP RMDFAAKLMK NIRFPLMTPQ ELINYVQTVD
       310        320        330        340        350        360
FMRTDNTCVN LLLEASNYQM MPYMQPVMQS DRTAIRSDTT HLVTLGGVLR QQLVVSKELR
       370        380        390        400        410        420
MYDEKAHEWK SLAPMDAPRY QHGIAVIGNF LYVVGGQSNY DTKGKTAVDT VFRFDPRYNK
       430        440        450        460        470        480
WMQVASLNEK RTFFHLSALK GYLYAVGGRN AAGELPTVEC YNPRTNEWTY VAKMSEPHYG
       490        500        510        520        530        540
HAGTVYGGVM YISGGITHDT FQKELMCFDP DTDKWIQKAP MTTVRGLHCM CTVGERLYVI
       550        560        570        580        590        600
GGNHFRGTSD YDDVLSCEYY SPILDQWTPI AAMLRGQSDV GVAVFENKIY VVGGYSWNNR
       610        620        630        640        650
CMVEIVQKYD PDKDEWHKVF DLPESLGGIR ACTLTVFPPE ETTPSPSRES PLSAP         10         20         30         40         50         60
MPLKWKTSSP AIWKFPVPVL KTSRSTPLSP AYISLVEEED QHMKLSLGGS EMGLSSHLQS
        70         80         90        100        110        120
SKAGPTRIFT SNTHSSVVLQ GFDQLRLEGL LCDVTLMPGD TDDAFPVHRV MMASASDYFK
       130        140        150        160        170        180
AMFTGGMKEQ DLMCIKLHGV SKVGLRKIID FIYTAKLSLN MDNLQDTLEA ASFLQILPVL
       190        200        210        220        230        240
DFCKVFLISG VTLDNCVEVG RIANTYNLTE VDKYVNSFVL KNFPALLSTG EFLKLPFERL
       250        260        270        280        290        300
AFVLSSNSLK HCTELELFKA TCRWLRLEEP RMDFAAKLMK NIRFPLMTPQ ELINYVQTVD
       310        320        330        340        350        360
FMRTDNTCVN LLLEASNYQM MPYMQPVMQS DRTAIRSDTT HLVTLGGVLR QQLVVSKELR
       370        380        390        400        410        420
MYDEKAHEWK SLAPMDAPRY QHGIAVIGNF LYVVGGQSNY DTKGKTAVDT VFRFDPRYNK
       430        440        450        460        470        480
WMQVASLNEK RTFFHLSALK GYLYAVGGRN AAGELPTVEC YNPRTNEWTY VAKMSEPHYG
       490        500        510        520        530        540
HAGTVYGGVM YISGGITHDT FQKELMCFDP DTDKWIQKAP MTTVRGLHCM CTVGERLYVI
       550        560        570        580        590        600
GGNHFRGTSD YDDVLSCEYY SPILDQWTPI AAMLRGQSDV GVAVFENKIY VVGGYSWNNR
       610        620        630        640        650
CMVEIVQKYD PDKDEWHKVF DLPESLGGIR ACTLTVFPPE ETTPSPSRES PLSAP         10         20         30         40         50         60
MPLKWKTSSP AIWKFPVPVL KTSRSTPLSP AYISLVEEED QHMKLSLGGS EMGLSSHLQS
        70         80         90        100        110        120
SKAGPTRIFT SNTHSSVVLQ GFDQLRLEGL LCDVTLMPGD TDDAFPVHRV MMASASDYFK
       130        140        150        160        170        180
AMFTGGMKEQ DLMCIKLHGV SKVGLRKIID FIYTAKLSLN MDNLQDTLEA ASFLQILPVL
       190        200        210        220        230        240
DFCKVFLISG VTLDNCVEVG RIANTYNLTE VDKYVNSFVL KNFPALLSTG EFLKLPFERL
       250        260        270        280        290        300
AFVLSSNSLK HCTELELFKA TCRWLRLEEP RMDFAAKLMK NIRFPLMTPQ ELINYVQTVD
       310        320        330        340        350        360
FMRTDNTCVN LLLEASNYQM MPYMQPVMQS DRTAIRSDTT HLVTLGGVLR QQLVVSKELR
       370        380        390        400        410        420
MYDEKAHEWK SLAPMDAPRY QHGIAVIGNF LYVVGGQSNY DTKGKTAVDT VFRFDPRYNK
       430        440        450        460        470        480
WMQVASLNEK RTFFHLSALK GYLYAVGGRN AAGELPTVEC YNPRTNEWTY VAKMSEPHYG
       490        500        510        520        530        540
HAGTVYGGVM YISGGITHDT FQKELMCFDP DTDKWIQKAP MTTVRGLHCM CTVGERLYVI
       550        560        570        580        590        600
GGNHFRGTSD YDDVLSCEYY SPILDQWTPI AAMLRGQSDV GVAVFENKIY VVGGYSWNNR
       610        620        630        640        650
CMVEIVQKYD PDKDEWHKVF DLPESLGGIR ACTLTVFPPE ETTPSPSRES PLSAP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9P2N7-1-unknown	MPLKWK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9P2N7-43-unknown	MKLSLG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79093
Q9P2N7-43-unknown	MKLSLG...	43	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440707
Q9P2N7-43-unknown	MKLSLG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109479
Q9P2N7-43-unknown	MKLSLG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109478
Q9P2N7-43-unknown	MKLSLG...	43	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109477
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000360949
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000360943
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000360945
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412640
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000419803
Q9P2N7-52-unknown	MGLSSH...	52	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393807
Q9P2N7-52-unknown	MGLSSH...	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196173
Q9P2N7-52-unknown	MGLSSH...	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196172
Q9P2N7-52-unknown	MGLSSH...	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196171
Q9P2N7-52-unknown	MGLSSH...	52	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196170

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QLRLEG	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393807
...QLRLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154258
...QLRLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154257
...QLRLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154256
...QLRLEG	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154255
...PLSAP	655	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...PLSAP	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74711
...PLSAP	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74712
...PLSAP	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74713
...PLSAP	655	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74714

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)