TopFIND 4.0

Q9QUG9: RAS guanyl-releasing protein 2

General Information

Protein names
- RAS guanyl-releasing protein 2
- Calcium and DAG-regulated guanine nucleotide exchange factor I
- CalDAG-GEFI
- F25B3.3 kinase-like protein
Gene names Rasgrp2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9QUG9

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTSTLDLDKG CTVEELLRGC IEAFDDSGKV RDPQLVRMFL MMHPWYIPSS QLASKLLHFY 
        70         80         90        100        110        120 
QQSRKDNSNS LQMKTCHLVR YWISAFPAEF DLNPELAEQI KELKALLDQE GNRRHSSLID 
       130        140        150        160        170        180 
IESVPTYKWK RQVTQRNPVE QKKRKMSLLF DHLEPMELAE HLTYLEYRSF CKILFQDYHS 
       190        200        210        220        230        240 
FVTHGCTVDN PVLERFISLF NSVSQWVQLM ILSKPTATQR ALVITHFVHV AERLLQLQNF 
       250        260        270        280        290        300 
NTLMAVVGGL SHSSISRLKE THSHVSPDTI KLWEGLTELV TATGNYSNYR RRLAACVGFR 
       310        320        330        340        350        360 
FPILGVHLKD LVALQLALPD WLDPGRTRLN GAKMRQLFCI LEELAMVTSL RPPVQANPDL 
       370        380        390        400        410        420 
LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP PPRPPVLEEW TSVAKPKLDQ 
       430        440        450        460        470        480 
ALVAEHIEKM VESVFRNFDV DGDGHISQEE FQIIRGNFPY LSAFGDLDQN QDGCISREEM 
       490        500        510        520        530        540 
ISYFLRSSSV LGGRMGFVHN FQESNSLRPV ACRHCKALIL GIYKQGLKCR ACGVNCHKQC 
       550        560        570        580        590        600 
KERLSVECRR RAQSVSLEGS APSPSPTHTH HRAFSFSLPR PGRRSSRPPE IREEEVQSVE 
   
DGVFDIHL

Isoforms

- Isoform 2 of RAS guanyl-releasing protein 2 - Isoform 3 of RAS guanyl-releasing protein 2

Sequence View

        10         20         30         40         50         60 
MTSTLDLDKG CTVEELLRGC IEAFDDSGKV RDPQLVRMFL MMHPWYIPSS QLASKLLHFY 
        70         80         90        100        110        120 
QQSRKDNSNS LQMKTCHLVR YWISAFPAEF DLNPELAEQI KELKALLDQE GNRRHSSLID 
       130        140        150        160        170        180 
IESVPTYKWK RQVTQRNPVE QKKRKMSLLF DHLEPMELAE HLTYLEYRSF CKILFQDYHS 
       190        200        210        220        230        240 
FVTHGCTVDN PVLERFISLF NSVSQWVQLM ILSKPTATQR ALVITHFVHV AERLLQLQNF 
       250        260        270        280        290        300 
NTLMAVVGGL SHSSISRLKE THSHVSPDTI KLWEGLTELV TATGNYSNYR RRLAACVGFR 
       310        320        330        340        350        360 
FPILGVHLKD LVALQLALPD WLDPGRTRLN GAKMRQLFCI LEELAMVTSL RPPVQANPDL 
       370        380        390        400        410        420 
LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP PPRPPVLEEW TSVAKPKLDQ 
       430        440        450        460        470        480 
ALVAEHIEKM VESVFRNFDV DGDGHISQEE FQIIRGNFPY LSAFGDLDQN QDGCISREEM 
       490        500        510        520        530        540 
ISYFLRSSSV LGGRMGFVHN FQESNSLRPV ACRHCKALIL GIYKQGLKCR ACGVNCHKQC 
       550        560        570        580        590        600 
KERLSVECRR RAQSVSLEGS APSPSPTHTH HRAFSFSLPR PGRRSSRPPE IREEEVQSVE 
   
DGVFDIHL         10         20         30         40         50         60 
MTSTLDLDKG CTVEELLRGC IEAFDDSGKV RDPQLVRMFL MMHPWYIPSS QLASKLLHFY 
        70         80         90        100        110        120 
QQSRKDNSNS LQMKTCHLVR YWISAFPAEF DLNPELAEQI KELKALLDQE GNRRHSSLID 
       130        140        150        160        170        180 
IESVPTYKWK RQVTQRNPVE QKKRKMSLLF DHLEPMELAE HLTYLEYRSF CKILFQDYHS 
       190        200        210        220        230        240 
FVTHGCTVDN PVLERFISLF NSVSQWVQLM ILSKPTATQR ALVITHFVHV AERLLQLQNF 
       250        260        270        280        290        300 
NTLMAVVGGL SHSSISRLKE THSHVSPDTI KLWEGLTELV TATGNYSNYR RRLAACVGFR 
       310        320        330        340        350        360 
FPILGVHLKD LVALQLALPD WLDPGRTRLN GAKMRQLFCI LEELAMVTSL RPPVQANPDL 
       370        380        390        400        410        420 
LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP PPRPPVLEEW TSVAKPKLDQ 
       430        440        450        460        470        480 
ALVAEHIEKM VESVFRNFDV DGDGHISQEE FQIIRGNFPY LSAFGDLDQN QDGCISREEM 
       490        500        510        520        530        540 
ISYFLRSSSV LGGRMGFVHN FQESNSLRPV ACRHCKALIL GIYKQGLKCR ACGVNCHKQC 
       550        560        570        580        590        600 
KERLSVECRR RAQSVSLEGS APSPSPTHTH HRAFSFSLPR PGRRSSRPPE IREEEVQSVE 
   
DGVFDIHL



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9QUG9-1-unknown MTSTLD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9QUG9-1-unknown MTSTLD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76509
    Q9QUG9-1-unknown MTSTLD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76510

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LDQNQD 471 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt72127
    ...FDIHL 608 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)