TopFIND 4.0

Q9QUK0: Cyclin-dependent kinase-like 2 {ECO:0000305}

General Information

Protein names
- Cyclin-dependent kinase-like 2 {ECO:0000305}
- 2.7.11.22
- Serine/threonine-protein kinase KKIAMRE
Gene names Cdkl2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9QUK0

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEKYENLGLV GEGSYGMVMK CRNKDSGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 
        70         80         90        100        110        120 
ENLVNLLEVC KKKKRWYLVF EFVDHTILDD LKLFPNGLDY QVVQKYLFQI INGIGFCHSH 
       130        140        150        160        170        180 
NIIHRDIKPE NILVSQSGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDVKYG 
       190        200        210        220        230        240 
KAVDIWAIGC LVIEMLMGQP LFPGESDIDQ LHHIMTCLGN LIPRHQELFY KNPVFAGVRL 
       250        260        270        280        290        300 
PEVKDAEAEP LESRYPKLPE AVISLAKKCL HIDPDKRPFC ADLLRHDFFQ MDGFAERFSQ 
       310        320        330        340        350        360 
ELQLKIEKDA RNNSLPKKSQ NRKKEKDDAL GEERKTLVVQ DTNADPKIKD SKVFKVKGSK 
       370        380        390        400        410        420 
IDVEKMEKGS RASNANCLHD NGTNHKGLAS TSLRDCSNVN IDHSRNPGTA IPPLTHNLSA 
       430        440        450        460        470        480 
VAPGINAGMG TIPGVQNYRV DEKTKKYCNP FVKPNQPPPA GIYNMNVSTS VSGEKYLLQA 
       490        500        510        520        530        540 
NKKRKEYPKA DVRLPELNYN HLPELRALEG IARNSRLIKK ENKCLSESRI PSLAAIDLHV 
       550        560    
SSVASHQGAG SPLSDDSEAD LPRMEHQH

Isoforms

- Isoform 2 of Cyclin-dependent kinase-like 2

Sequence View

        10         20         30         40         50         60 
MEKYENLGLV GEGSYGMVMK CRNKDSGRIV AIKKFLESDD DKMVKKIAMR EIKLLKQLRH 
        70         80         90        100        110        120 
ENLVNLLEVC KKKKRWYLVF EFVDHTILDD LKLFPNGLDY QVVQKYLFQI INGIGFCHSH 
       130        140        150        160        170        180 
NIIHRDIKPE NILVSQSGVV KLCDFGFART LAAPGEVYTD YVATRWYRAP ELLVGDVKYG 
       190        200        210        220        230        240 
KAVDIWAIGC LVIEMLMGQP LFPGESDIDQ LHHIMTCLGN LIPRHQELFY KNPVFAGVRL 
       250        260        270        280        290        300 
PEVKDAEAEP LESRYPKLPE AVISLAKKCL HIDPDKRPFC ADLLRHDFFQ MDGFAERFSQ 
       310        320        330        340        350        360 
ELQLKIEKDA RNNSLPKKSQ NRKKEKDDAL GEERKTLVVQ DTNADPKIKD SKVFKVKGSK 
       370        380        390        400        410        420 
IDVEKMEKGS RASNANCLHD NGTNHKGLAS TSLRDCSNVN IDHSRNPGTA IPPLTHNLSA 
       430        440        450        460        470        480 
VAPGINAGMG TIPGVQNYRV DEKTKKYCNP FVKPNQPPPA GIYNMNVSTS VSGEKYLLQA 
       490        500        510        520        530        540 
NKKRKEYPKA DVRLPELNYN HLPELRALEG IARNSRLIKK ENKCLSESRI PSLAAIDLHV 
       550        560    
SSVASHQGAG SPLSDDSEAD LPRMEHQH



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Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9QUK0-1-unknown MEKYEN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9QUK0-1-unknown MEKYEN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70126

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MEHQH 568 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)