TopFIND 4.0

Q9QXP6: E3 ubiquitin-protein ligase makorin-1

General Information

Protein names
- E3 ubiquitin-protein ligase makorin-1
- 2.3.2.27
- RING-type E3 ubiquitin transferase makorin-1 {ECO:0000305}
Gene names Mkrn1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9QXP6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAEAAAPGTT ATTSGAGAAA AAVAAASLTS IPTVAAPSPG AGGGGGGSDG SGGGWTKQVT 
        70         80         90        100        110        120 
CRYFMHGVCK EGDNCRYSHD LSDSPYGVVC KYFQRGYCVY GDRCRYEHSK PLKQEEVTAT 
       130        140        150        160        170        180 
DLSAKPSLAA SSSLSSGVGS LAEMNSGEAE SRNPSFPTVG AGSEDWVNAI EFVPGQPYCG 
       190        200        210        220        230        240 
RTAPSCTEVP PQGSVTKEES EKEPTTVETK KQLCPYAAVG ECRYGENCVY LHGDSCDMCG 
       250        260        270        280        290        300 
LQVLHPVDAA QRSQHIKSCI EAHEKDMELS FAVQRTKDMV CGICMEVVYE KANPSERRFG 
       310        320        330        340        350        360 
ILSNCNHTYC LKCIRKWRSA KQFESKIIKS CPECRITSNF VIPSEYWVEE KEEKQKLIQK 
       370        380        390        400        410        420 
YKEAMSNKAC RYFDEGRGSC PFGGNCFYKH AYPDGRREEP QRQKVGTSSR YRAQRRSHFW 
       430        440        450        460        470        480 
ELIEERENNP FDNDEEEVVT FELGEMLLML LAAGGDDELT DSEDEWDLFH DELEDFYDLD 
   
L

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase makorin-1

Sequence View

        10         20         30         40         50         60 
MAEAAAPGTT ATTSGAGAAA AAVAAASLTS IPTVAAPSPG AGGGGGGSDG SGGGWTKQVT 
        70         80         90        100        110        120 
CRYFMHGVCK EGDNCRYSHD LSDSPYGVVC KYFQRGYCVY GDRCRYEHSK PLKQEEVTAT 
       130        140        150        160        170        180 
DLSAKPSLAA SSSLSSGVGS LAEMNSGEAE SRNPSFPTVG AGSEDWVNAI EFVPGQPYCG 
       190        200        210        220        230        240 
RTAPSCTEVP PQGSVTKEES EKEPTTVETK KQLCPYAAVG ECRYGENCVY LHGDSCDMCG 
       250        260        270        280        290        300 
LQVLHPVDAA QRSQHIKSCI EAHEKDMELS FAVQRTKDMV CGICMEVVYE KANPSERRFG 
       310        320        330        340        350        360 
ILSNCNHTYC LKCIRKWRSA KQFESKIIKS CPECRITSNF VIPSEYWVEE KEEKQKLIQK 
       370        380        390        400        410        420 
YKEAMSNKAC RYFDEGRGSC PFGGNCFYKH AYPDGRREEP QRQKVGTSSR YRAQRRSHFW 
       430        440        450        460        470        480 
ELIEERENNP FDNDEEEVVT FELGEMLLML LAAGGDDELT DSEDEWDLFH DELEDFYDLD 
   
L



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9QXP6-1-unknown MAEAAA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9QXP6-1-unknown MAEAAA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81237

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...YDLDL 481 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)