Q9QZL0: Receptor-interacting serine/threonine-protein kinase 3

General Information

Protein names	- Receptor-interacting serine/threonine-protein kinase 3 - 2.7.11.1 - RIP-like protein kinase 3 - Receptor-interacting protein 3 - RIP-3 - mRIP3
Gene names	Ripk3
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9QZL0

3 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSVKLWPTG ASAVPLVSRE ELKKLEFVGK GGFGVVFRAH HRTWNHDVAV KIVNSKKISW
        70         80         90        100        110        120
EVKAMVNLRN ENVLLLLGVT EDLQWDFVSG QALVTRFMEN GSLAGLLQPE CPRPWPLLCR
       130        140        150        160        170        180
LLQEVVLGMC YLHSLNPPLL HRDLKPSNIL LDPELHAKLA DFGLSTFQGG SQSGSGSGSG
       190        200        210        220        230        240
SRDSGGTLAY LDPELLFDVN LKASKASDVY SFGILVWAVL AGREAELVDK TSLIRETVCD
       250        260        270        280        290        300
RQSRPPLTEL PPGSPETPGL EKLKELMIHC WGSQSENRPS FQDCEPKTNE VYNLVKDKVD
       310        320        330        340        350        360
AAVSEVKHYL SQHRSSGRNL SAREPSQRGT EMDCPRETMV SKMLDRLHLE EPSGPVPGKC
       370        380        390        400        410        420
PERQAQDTSV GPATPARTSS DPVAGTPQIP HTLPFRGTTP GPVFTETPGP HPQRNQGDGR
       430        440        450        460        470        480
HGTPWYPWTP PNPMTGPPAL VFNNCSEVQI GNYNSLVAPP RTTASSSAKY DQAQFGRGRG

WQPFHK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9QZL0-1-unknown	MSSVKL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9QZL0-28-unknown	VGKGGF...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31290
Q9QZL0-65-unknown	MVNLRN...	65	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126306
Q9QZL0-65-unknown	MVNLRN...	65	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000137278

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KKLEFV	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC31290
	...QPFHK	486	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	27	LEFV.\|.VGKG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> RIPK3_MOUSE @27

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)