TopFIND 4.0

Q9R049: E3 ubiquitin-protein ligase AMFR

General Information

Protein names
- E3 ubiquitin-protein ligase AMFR
- 2.3.2.27 {ECO:0000250|UniProtKB:Q9UKV5}
- Autocrine motility factor receptor
- AMF receptor
- RING-type E3 ubiquitin transferase AMFR {ECO:0000305}
Gene names Amfr
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9R049

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPLLFLERFP WPSLRTYTGL SGLALLGTIV SAYRALSQPE DGSGEPEPLT APLQPEALAP 
        70         80         90        100        110        120 
ARLTAGGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 
       130        140        150        160        170        180 
KFWNFIFYKF IFIFGVLNVQ TVEEVVMWCL WFAGLVFLHL MVQLCKDRFE YLSFSPTTPM 
       190        200        210        220        230        240 
SSHGRVLSLL IAMLLSCCGL AVVCCVTGYT HGMHTLAFMA AESLLVTVRT AHVILRYVIH 
       250        260        270        280        290        300 
LWDLNHEGTW EGKGTYVYYT DFVMELALLS LDLMHHIHML LFGNIWLSMA SLVIFMQLRY 
       310        320        330        340        350        360 
LFHEVQRRIR RHKNYLRVVG NMEARFAVAT PEELAVNNDD CAICWDSMQA ARKLPCGHLF 
       370        380        390        400        410        420 
HNSCLRSWLE QDTSCPTCRM SLNIADGSRA REDHQGENLD ENLVPVAAAE GRPRLNQHNH 
       430        440        450        460        470        480 
FFHFDGSRIA SWLPSFSVEV MHTTNILGIT QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL 
       490        500        510        520        530        540 
QMTRSVEITT DNILEGRIQV PFPTQRSDSL RPALNSPVER PSPDLEEGEA SVQTERVPLD 
       550        560        570        580        590        600 
LSPRLEETLD FSEVELEPIE VEDFEARGSR FSKSADERQR MLVQRKDDLL QQARKRFLNK 
       610        620        630        640    
SSEDDGASER LLPSEGTSSD PVTLRRRMLA AAAERRLQRQ RTT

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase AMFR

Sequence View

        10         20         30         40         50         60 
MPLLFLERFP WPSLRTYTGL SGLALLGTIV SAYRALSQPE DGSGEPEPLT APLQPEALAP 
        70         80         90        100        110        120 
ARLTAGGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 
       130        140        150        160        170        180 
KFWNFIFYKF IFIFGVLNVQ TVEEVVMWCL WFAGLVFLHL MVQLCKDRFE YLSFSPTTPM 
       190        200        210        220        230        240 
SSHGRVLSLL IAMLLSCCGL AVVCCVTGYT HGMHTLAFMA AESLLVTVRT AHVILRYVIH 
       250        260        270        280        290        300 
LWDLNHEGTW EGKGTYVYYT DFVMELALLS LDLMHHIHML LFGNIWLSMA SLVIFMQLRY 
       310        320        330        340        350        360 
LFHEVQRRIR RHKNYLRVVG NMEARFAVAT PEELAVNNDD CAICWDSMQA ARKLPCGHLF 
       370        380        390        400        410        420 
HNSCLRSWLE QDTSCPTCRM SLNIADGSRA REDHQGENLD ENLVPVAAAE GRPRLNQHNH 
       430        440        450        460        470        480 
FFHFDGSRIA SWLPSFSVEV MHTTNILGIT QASNSQLNAM AHQIQEMFPQ VPYHLVLQDL 
       490        500        510        520        530        540 
QMTRSVEITT DNILEGRIQV PFPTQRSDSL RPALNSPVER PSPDLEEGEA SVQTERVPLD 
       550        560        570        580        590        600 
LSPRLEETLD FSEVELEPIE VEDFEARGSR FSKSADERQR MLVQRKDDLL QQARKRFLNK 
       610        620        630        640    
SSEDDGASER LLPSEGTSSD PVTLRRRMLA AAAERRLQRQ RTT



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9R049-1-unknown MPLLFL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9R049-1-unknown MPLLFL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66797
    Q9R049-93-unknown CVLMLV... 93 inferred from electronic annotation unknown TISdb inferred from TISdb
    Q9R049-93-unknown CVLMLV... 93 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt196833

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RQRTT 643 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RQRTT 643 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt62415

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)