TopFIND 4.0

Q9R0G8: Nik-related protein kinase

General Information

Protein names
- Nik-related protein kinase
- 2.7.11.1
- Nck-interacting kinase-like embryo specific kinase
- NESK
- NIK-like embryo-specific kinase
Gene names Nrk
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9R0G8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGPGSWRDK EVTDLGQLPD PTGIFSLDKA IGLGTYGRIF LGIHEKTGSL VAVKVMSARK 
        70         80         90        100        110        120 
TPLPEIGRRV RVNKYQKSVG WRYSDEEEDL RTELNLLRKY SFHKNIVTFY GAFFKLNPPG 
       130        140        150        160        170        180 
HQHQLWMVME LCAAGSVTDV VRMTRNQSLK EDWIAYICRE ILQGLAHLHA HQVIHRDIKG 
       190        200        210        220        230        240 
QNVLLTHDAE VKIVDFGVSA QVSRTNGRRN SFIGTPYWMA PEVIHCDEDP RCSYDYRSDV 
       250        260        270        280        290        300 
WSVGITAIEM AEGAPPLCKL QPLEALCVIL REAAPKVKSS GWSRKFQNFM ENCMIKNFLF 
       310        320        330        340        350        360 
RPTSGNMLLH PFVHDIKNER RVVESLTKHL TGIIQKREKK GIPVAFEGEE AAKEQYITRR 
       370        380        390        400        410        420 
FRGPSCTPEL LRVPTSSRCR PLRVLHGEPP QPRWLPDQED PQDQELQQLQ KAAGVFMPLH 
       430        440        450        460        470        480 
SQDNTSKLFP KQVEVAPYLR GAAQVVMPVL VQVEAPPQVS KAAQMLKSLP TQDNKATSPE 
       490        500        510        520        530        540 
VQAPVAEGQQ AQHEALETEQ PKDLDQVPEE FQGQDRAPEQ PRQGQAAEQQ QIHNPVPEQP 
       550        560        570        580        590        600 
PEEDREPEQA EVQEEAVEPP QAEIEDKEPE VVQVHAQVLL PLLSQNRHVL LPLHLDRQLL 
       610        620        630        640        650        660 
IPVGEQNEEV PRAQAWDLEA SRAVGAVQAL IEGLSRDLLR APNAFVTKPL GPLQIFLENL 
       670        680        690        700        710        720 
STDGFYTEPE PTQKKKSKVA SLRKAIAKRL RPKRFRAKAL WRLEDFEFSD VETSRRRRHR 
       730        740        750        760        770        780 
RWEDIFNQHE EQLRRVENDR EDDSSDNDEV FHSIQAEVQI EPHAANPAGN EVHERSAPMP 
       790        800        810        820        830        840 
CNRNRTHRVK FSPSVGEEEP SLEEAQPQQQ QQQPMNIRPR NCLNPQNFQA QSDSSSEEDS 
       850        860        870        880        890        900 
PVTRRKSQSS PPYSTIDQKL LIDIHVPDGF KVGKISPPVY LTNEWVGYNA LSEIFWDDWI 
       910        920        930        940        950        960 
MPTRPARPPE EDGDYVELYD ADANANGDEE VANGAYEDPR DGANGHDDMN NQLDQANGYE 
       970        980        990       1000       1010       1020 
GHGAAGYNGG DVGGNHGAAF NGPRANYPRA GILKNGHNDG RALNRGAFGV FGDNAARAFH 
      1030       1040       1050       1060       1070       1080 
GAAGEAGAAF GNHGANRGNG RGNRNREANG RNEENGAFGR DQHVFPEFEH EESDRGTETS 
      1090       1100       1110       1120       1130       1140 
DSIALEITSF DGEQNSGRPV SSTTMGFPIG RSSPRGSDFG SDISYNSPIL HVYEKDFSSE 
      1150       1160       1170       1180       1190       1200 
VYCGSLWGVN LLLGTQSHLY LMDRSGKAEI VKLIKRRPFR QIQVVEQLNL LITISGKKNR 
      1210       1220       1230       1240       1250       1260 
LRVYHLSWLR NKILNNDPKS KKRQKAMRKK EEACKAIDKL IGCEHFSVLQ HEETTYIAVA 
      1270       1280       1290       1300       1310       1320 
VKSSIHLFAW APKSFDENTA IKVFPTRDLK PLTVDLAVGS EKTLKIFFSS ANGYHIIDAE 
      1330       1340       1350       1360       1370       1380 
SEVMSEVTLP NNNVVILPDC LGLGVMLSLN AEAASEEANE QLLKKILDVW KDIPSSVAFE 
      1390       1400       1410       1420       1430       1440 
CTKRITGWDQ KAIEVRSLQS TILENELKRR SIKKLRFLCA RGDKMFFAST LSNDHSRVYL 
      1450    
MSLGKLEELH RSYAV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9R0G8-1-unknown MAGPGS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RSYAV 1455 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)