Q9R0S3: Matrix metalloproteinase-17
Protein names | - Matrix metalloproteinase-17 - MMP-17 - 3.4.24.- - Membrane-type matrix metalloproteinase 4 - MT-MMP 4 - MTMMP4 - Membrane-type-4 matrix metalloproteinase - MT4-MMP - MT4MMP |
---|---|
Gene names | Mmp17 |
Organism | Mus musculus |
Protease Family | M10.017 |
Protease ID | M10.017 |
Chromosome location | |
UniProt ID | Q9R0S3 |
2
N-termini
1
C-termini
0
Cleavages
79
Substrates
Sequence
10 20 30 40 50 60
MGRRPRGPGS PRGPGPPRPG PGLPPLLLVL ALAAHGGCAA PAPRAEDLSL GVEWLSRFGY
70 80 90 100 110 120
LPPADPASGQ LQTQEELSKA ITAMQQFGGL ETTGILDEAT LALMKTPRCS LPDLPPGAQS
130 140 150 160 170 180
RRKRQTPPPT KWSKRNLSWR VRTFPRDSPL GRDTVRALMY YALKVWSDIT PLNFHEVAGN
190 200 210 220 230 240
AADIQIDFSK ADHNDGYPFD GPGGTVAHAF FPGDHHTAGD THFDDDEPWT FRSSDAHGMD
250 260 270 280 290 300
LFAVAVHEFG HAIGLSHVAA PSSIMQPYYQ GPVGDPLRYG LPYEDRVRVW QLYGVRESVS
310 320 330 340 350 360
PTAQLDTPEP EEPPLLPEPP NNRSSTPPQK DVPHRCTAHF DAVAQIRGEA FFFKGKYFWR
370 380 390 400 410 420
LTRDRHLVSL QPAQMHRFWR GLPLHLDSVD AVYERTSDHK IVFFKGDRYW VFKDNNVEEG
430 440 450 460 470 480
YPRPVSDFSL PPGGIDAVFS WAHNDRTYFF KDQLYWRYDD HTRRMDPGYP AQGPLWRGVP
490 500 510 520 530 540
SMLDDAMRWS DGASYFFRGQ EYWKVLDGEL EAAPGYPQST ARDWLVCGEP LADAEDVGPG
550 560 570
PQGRSGAQDG LAVCSCTSDA HRLALPSLLL LTPLLWGL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 79 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9R0S3-40-unknown | APAPRA... | 40 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9R0S3-125-unknown | QTPPPT... | 125 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9R0S3-125-unknown | QTPPPT... | 125 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...CSCTSD | 558 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
MBP-Isoform9_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform8_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform7_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform6_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform5_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform4_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform14_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform13_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform11_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform10_MOUSE | 11 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP-Isoform9_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform8_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform7_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform6_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform5_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform4_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform14_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform13_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform11_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform10_MOUSE | 13 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP-Isoform9_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform8_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform7_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform6_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform5_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform4_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform14_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform13_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform11_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform10_MOUSE | 25 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP-Isoform8_MOUSE | 70 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform7_MOUSE | 70 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform5_MOUSE | 70 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform14_MOUSE | 70 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform10_MOUSE | 70 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform8_MOUSE | 72 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform7_MOUSE | 72 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform5_MOUSE | 72 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform14_MOUSE | 72 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform10_MOUSE | 72 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP_MOUSE | 75 | PKNN.|.NWQG | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 75 | PKNN.|.NWQG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32975 | ||
MBP-Isoform8_MOUSE | 75 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform7_MOUSE | 75 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform5_MOUSE | 75 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform14_MOUSE | 75 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform10_MOUSE | 75 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform2_MOUSE | 87 | PGNR.|.RPHL | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32977 | ||
MBP_MOUSE | 87 | PGNR.|.RPHL | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform9_MOUSE | 96 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform6_MOUSE | 96 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform4_MOUSE | 96 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform13_MOUSE | 96 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform11_MOUSE | 96 | SLPQ.|.QKSQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33021 | ||
MBP-Isoform9_MOUSE | 98 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform6_MOUSE | 98 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform4_MOUSE | 98 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform13_MOUSE | 98 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform11_MOUSE | 98 | PQKS.|.SQHG | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33032 | ||
MBP-Isoform9_MOUSE | 101 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform6_MOUSE | 101 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform4_MOUSE | 101 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform13_MOUSE | 101 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform11_MOUSE | 101 | SQHG.|.GRTQ | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33043 | ||
MBP-Isoform2_MOUSE | 116 | SDEL.|.LQTI | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32979 | ||
MBP_MOUSE | 116 | SDEL.|.LQTI | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 135 | VMAS.|.SQKR | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32981 | ||
MBP_MOUSE | 135 | VMAS.|.SQKR | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 136 | MASQ.|.QKRP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32983 | ||
MBP_MOUSE | 136 | MASQ.|.QKRP | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 144 | QRSK.|.KYLA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32985 | ||
MBP_MOUSE | 144 | QRSK.|.KYLA | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 146 | SKYL.|.LATA | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC32997 | ||
MBP_MOUSE | 146 | SKYL.|.LATA | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP_MOUSE | 158 | ARHG.|.GFLP | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP-Isoform2_MOUSE | 158 | ARHG.|.GFLP | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TC33009 | ||
MBP_MOUSE | 203 | SLPQ.|.QKSQ | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP_MOUSE | 205 | PQKS.|.SQHG | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |
MBP_MOUSE | 208 | SQHG.|.GRTQ | inferred from experiment | unknown | MEROPS | Strongin AY | Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) | 19300513, |