TopFIND 4.0

Q9R172: Neurogenic locus notch homolog protein 3

General Information

Protein names
- Neurogenic locus notch homolog protein 3
- Notch 3
- Notch 3 extracellular truncation
- Notch 3 intracellular domain
Gene names Notch3
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9R172

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPGARGRRR RRRLMALPPP PPPMRALPLL LLLLAGLGAA APPCLDGSPC ANGGRCTHQQ 
        70         80         90        100        110        120 
PSREAACLCL PGWVGERCQL EDPCHSGPCA GRGVCQSSVV AGVARFSCRC LRGFRGPDCS 
       130        140        150        160        170        180 
LPDPCFSSPC AHGAPCSVGS DGRYACACPP GYQGRNCRSD IDECRAGASC RHGGTCINTP 
       190        200        210        220        230        240 
GSFHCLCPLG YTGLLCENPI VPCAPSPCRN GGTCRQSSDV TYDCACLPGF EGQNCEVNVD 
       250        260        270        280        290        300 
DCPGHRCLNG GTCVDGVNTY NCQCPPEWTG QFCTEDVDEC QLQPNACHNG GTCFNLLGGH 
       310        320        330        340        350        360 
SCVCVNGWTG ESCSQNIDDC ATAVCFHGAT CHDRVASFYC ACPMGKTGLL CHLDDACVSN 
       370        380        390        400        410        420 
PCHEDAICDT NPVSGRAICT CPPGFTGGAC DQDVDECSIG ANPCEHLGRC VNTQGSFLCQ 
       430        440        450        460        470        480 
CGRGYTGPRC ETDVNECLSG PCRNQATCLD RIGQFTCICM AGFTGTFCEV DIDECQSSPC 
       490        500        510        520        530        540 
VNGGVCKDRV NGFSCTCPSG FSGSTCQLDV DECASTPCRN GAKCVDQPDG YECRCAEGFE 
       550        560        570        580        590        600 
GTLCERNVDD CSPDPCHHGR CVDGIASFSC ACAPGYTGIR CESQVDECRS QPCRYGGKCL 
       610        620        630        640        650        660 
DLVDKYLCRC PPGTTGVNCE VNIDDCASNP CTFGVCRDGI NRYDCVCQPG FTGPLCNVEI 
       670        680        690        700        710        720 
NECASSPCGE GGSCVDGENG FHCLCPPGSL PPLCLPANHP CAHKPCSHGV CHDAPGGFQC 
       730        740        750        760        770        780 
VCDPGWSGPR CSQSLAPDAC ESQPCQAGGT CTSDGIGFHC TCAPGFQGHQ CEVLSPCTPS 
       790        800        810        820        830        840 
LCEHGGHCES DPDQLTVCSC PPGWQGPRCQ QDVDECAGAS PCGPHGTCTN LPGSFRCICH 
       850        860        870        880        890        900 
GGYTGPFCDQ DIDDCDPNPC LNGGSCQDGV GSFSCSCLSG FAGPRCARDV DECLSSPCGP 
       910        920        930        940        950        960 
GTCTDHVASF TCTCPPGYGG FHCETDLLDC SPSSCFNGGT CVDGVNSFSC LCRPGYTGTH 
       970        980        990       1000       1010       1020 
CQYKVDPCFS RPCLHGGICN PTHSGFECTC REGFTGNQCQ NPVDWCSQAP CQNGGRCVQT 
      1030       1040       1050       1060       1070       1080 
GAYCICPPEW SGPLCDIPSL PCTEAAAHMG VRLEQLCQAG GQCIDKDHSH YCVCPEGRMG 
      1090       1100       1110       1120       1130       1140 
SHCEQEVDPC TAQPCQHGGT CRGYMGGYVC ECPTGYSGDS CEDDVDECAS QPCQNGGSCI 
      1150       1160       1170       1180       1190       1200 
DLVAHYLCSC PPGTLGVLCE INEDDCGPGP SLDSGLRCLH NGTCVDLVGG FRCNCPPGYT 
      1210       1220       1230       1240       1250       1260 
GLHCEADINE CRPGTCHAAH TRDCLQDPGG HFRCICLPGF TGPRCQTALF PCESQPCQHG 
      1270       1280       1290       1300       1310       1320 
GQCRPSLGRG GGLTFTCHCV QPFWGLRCER VARSCRELQC PVGIPCQQTA RGPRCACPPG 
      1330       1340       1350       1360       1370       1380 
LSGPSCRVSR ASPSGATNTS CAATPCLHGG SCLPVQSVPF FRCVCAPGWG GPRCETPSAA 
      1390       1400       1410       1420       1430       1440 
PEVPEEPRCP RAACQAKRGD QNCDRECNSP GCGWDGGDCS LNVDDPWRQC EALQCWRLFN 
      1450       1460       1470       1480       1490       1500 
NSRCDPACSS PACLYDNFDC YSGGRDRTCN PVYKKYCADH FADGRCDQGC NTEECGWDGL 
      1510       1520       1530       1540       1550       1560 
DCASEVPALL ARGVLVLTVL LPPEELLRSS ADFLQRLSAI LRTSLRFRLD ARGQAMVFPY 
      1570       1580       1590       1600       1610       1620 
HRPSPGSESR VRRELGPEVI GSVVMLEIDN RLCLKSAEND HCFPDAQSAA DYLGALSAVE 
      1630       1640       1650       1660       1670       1680 
RLDFPYPLRD VRGEPLEPPE QSVPLLPLLV AGAVFLLVIF VLGVMVARRK REHSTLWFPE 
      1690       1700       1710       1720       1730       1740 
GFALHKDIAA GHKGRREPVG QDALGMKNMT KGESLMGEVA TDWNDSECPE AKRLKVEEPG 
      1750       1760       1770       1780       1790       1800 
MGAEEPVDCR QWTQHHLVAA DIRVAPAMAL TPPQGDADAD GMDVNVRGPD GFTPLMLASF 
      1810       1820       1830       1840       1850       1860 
CGGALEPMPA EEDEADDTSA SIISDLICQG AQLGARTDRT GETALHLAAR YARADAAKRL 
      1870       1880       1890       1900       1910       1920 
LDAGADTNAQ DHSGRTPLHT AVTADAQGVF QILIRNRSTD LDARMADGST ALILAARLAV 
      1930       1940       1950       1960       1970       1980 
EGMVEELIAS HADVNAVDEL GKSALHWAAA VNNVEATLAL LKNGANKDMQ DSKEETPLFL 
      1990       2000       2010       2020       2030       2040 
AAREGSYEAA KLLLDHFANR EITDHLDRLP RDVAQERLHQ DIVRLLDQPS GPRSPSGPHG 
      2050       2060       2070       2080       2090       2100 
LGPLLCPPGA FLPGLKAVQS GTKKSRRPPG KTGLGPQGTR GRGKKLTLAC PGPLADSSVT 
      2110       2120       2130       2140       2150       2160 
LSPVDSLDSP RPFGGPPASP GGFPLEGPYA TTATTVSLAQ LGASRAGPLG RQPPGGCVLS 
      2170       2180       2190       2200       2210       2220 
LGLLNPVAVP LDWARLPPPA PPGPSFLLPL APGSQLLNPA TPVSPHERPP PYLAAPGHGE 
      2230       2240       2250       2260       2270       2280 
EYPAAGTHSS PTKARFLRVP SEHPYLTPSP ESPEHWASPS PPSLSDWSDS TPSPATATSA 
      2290       2300       2310    
TAAGALPAQP HPISVPSLPQ SQTQLGPQPE VTPKRQVMA

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9R172-41-unknown APPCLD... 41 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9R172-1631-unknown VRGEPL... 1631 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9R172-1664-unknown VMVARR... 1664 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RQVMA 2319 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)