Q9R1P0: Proteasome subunit alpha type-4

General Information

Protein names	- Proteasome subunit alpha type-4 - 3.4.25.1 {ECO:0000250\|UniProtKB:P25789} - Macropain subunit C9 - Multicatalytic endopeptidase complex subunit C9 - Proteasome component C9 - Proteasome subunit L
Gene names	Psma4
Organism	Mus musculus
Protease Family
Protease ID	T01.973
Chromosome location
UniProt ID	Q9R1P0

5 N-termini

5 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSRRYDSRTT IFSPEGRLYQ VEYAMEAIGH AGTCLGILAN DGVLLAAERR NIHKLLDEVF
        70         80         90        100        110        120
FSEKIYKLNE DMACSVAGIT SDANVLTNEL RLIAQRYLLQ YQEPIPCEQL VTALCDIKQA
       130        140        150        160        170        180
YTQFGGKRPF GVSLLYIGWD KHYGFQLYQS DPSGNYGGWK ATCIGNNSAA AVSMLKQDYK
       190        200        210        220        230        240
EGEMTLKSAL ALAVKVLNKT MDVSKLSAEK VEIATLTRES GKTVIRVLKQ KEVEQLIKKH
       250        260
EEEEAKAERE KKEKEQREKD K

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9R1P0-1-unknown	MSRRYD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9R1P0-15-unknown	EGRLYQ...	15	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9R1P0-36-unknown	GILAND...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31307
Q9R1P0-41-unknown	DGVLLA...	41	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9R1P0-73-unknown	ACSVAG...	73	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31308

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AGTCLG	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31307
...LNEDMA	72	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31308
...LYIGWD	139	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000132368
...LSAEKV	210	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000126844
...REKDK	261	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	35	TCLG.\|.GILA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA4_MOUSE @35
CATE_MOUSE	72	EDMA.\|.ACSV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> PSA4_MOUSE @72

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)