Q9R1T4: Septin-6

General Information

Protein names	- Septin-6
Gene names	Sept6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9R1T4

6 N-termini

5 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform I of Septin-6 - Isoform V of Septin-6

Sequence View

        10         20         30         40         50         60
MAAADIARQV GEDCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
        70         80         90        100        110        120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVGLKLTIV STVGFGDQIN KEDSYKPIVE
       130        140        150        160        170        180
FIDAQFEAYL QEELKIRRVL HSYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
       190        200        210        220        230        240
PVIAKSDAIS KSELAKFKIK ITSELVSNGV QIYQFPTDDE SVSEINGTMN AHLPFAVVGS
       250        260        270        280        290        300
TEEVKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HARHYELYRR
       310        320        330        340        350        360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
       370        380        390        400        410        420
EKELHEKFDR LKKLHQEEKK KLEDKKKCLD EEMNAFKQRK AAAELLQSQG SQAGGSQTLK
       430
RDKEKKNNPW LCIE         10         20         30         40         50         60
MAAADIARQV GEDCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
        70         80         90        100        110        120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVGLKLTIV STVGFGDQIN KEDSYKPIVE
       130        140        150        160        170        180
FIDAQFEAYL QEELKIRRVL HSYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
       190        200        210        220        230        240
PVIAKSDAIS KSELAKFKIK ITSELVSNGV QIYQFPTDDE SVSEINGTMN AHLPFAVVGS
       250        260        270        280        290        300
TEEVKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HARHYELYRR
       310        320        330        340        350        360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
       370        380        390        400        410        420
EKELHEKFDR LKKLHQEEKK KLEDKKKCLD EEMNAFKQRK AAAELLQSQG SQAGGSQTLK
       430
RDKEKKNNPW LCIE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9R1T4-2-unknown	MAAADI...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9R1T4-2-unknown	MAAADI...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9R1T4-1-unknown	MAAADI...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89295
Q9R1T4-1-unknown	MAAADI...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt89296
Q9R1T4-2-Acetylation	AAADIA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9R1T4-2-Acetylation	AAADIA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110466
Q9R1T4-2-Acetylation	AAADIA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110467
Q9R1T4-2-Acetylation	AAADIA...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q9R1T4-321-unknown	QETYEA...	321		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31316
Q9R1T4-321-unknown	QETYEA...	321		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150358
Q9R1T4-321-unknown	QETYEA...	321		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150359
Q9R1T4-406-unknown	LQSQGS...	406		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31319
Q9R1T4-406-unknown	LQSQGS...	406		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152084
Q9R1T4-406-unknown	LQSQGS...	406		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152085
Q9R1T4-407-unknown	QSQGSQ...	407		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31322
Q9R1T4-407-unknown	QSQGSQ...	407		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152106
Q9R1T4-407-unknown	QSQGSQ...	407		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt152107

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KPFSLQ	320	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31316
...KPFSLQ	320	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133755
...KPFSLQ	320	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133756
...AAAELL	405	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31319
...AAAELL	405	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135493
...AAAELL	405	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135494
...AAELLQ	406	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31322
...AAELLQ	406	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135515
...AAELLQ	406	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt135516
...KEKKNN	427	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt84913
...KEKKNN	427	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92735
...WLCIE	434	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	320	FSLQ.\|.QETY	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SEPT6_MOUSE @320
CATE_MOUSE	405	AELL.\|.LQSQ	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SEPT6_MOUSE @405
CATE_MOUSE	406	ELLQ.\|.QSQG	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> SEPT6_MOUSE @406

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)