TopFIND 4.0

Q9R1T7: Inducible T-cell costimulator

General Information

Protein names
- Inducible T-cell costimulator
- Activation-inducible lymphocyte immunomediatory molecule
- CD278
Gene names Icos
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9R1T7

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKPYFSCVFV FCFLIKLLTG ELNDLANHRM FSFHDGGVQI SCNYPETVQQ LKMQLFKDRE 
        70         80         90        100        110        120 
VLCDLTKTKG SGNTVSIKNP MSCPYQLSNN SVSFFLDNAD SSQGSYFLCS LSIFDPPPFQ 
       130        140        150        160        170        180 
EKNLSGGYLL IYESQLCCQL KLWLPVGCAA FVAALLFGCI FIVWFAKKKY RSSVHDPNSE 
       190        200    
YMFMAAVNTN KKSRLAGMTS 

Isoforms

- Isoform 2 of Inducible T-cell costimulator

Sequence View

        10         20         30         40         50         60 
MKPYFSCVFV FCFLIKLLTG ELNDLANHRM FSFHDGGVQI SCNYPETVQQ LKMQLFKDRE 
        70         80         90        100        110        120 
VLCDLTKTKG SGNTVSIKNP MSCPYQLSNN SVSFFLDNAD SSQGSYFLCS LSIFDPPPFQ 
       130        140        150        160        170        180 
EKNLSGGYLL IYESQLCCQL KLWLPVGCAA FVAALLFGCI FIVWFAKKKY RSSVHDPNSE 
       190        200    
YMFMAAVNTN KKSRLAGMTS 



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9R1T7-1-unknown MKPYFS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt192787
    Q9R1T7-21-unknown ELNDLA... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9R1T7-21-unknown ELNDLA... 21 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195227

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AGMTS 200 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)