TopFIND 4.0

Q9UBF9: Myotilin

General Information

Protein names
- Myotilin
- 57 kDa cytoskeletal protein
- Myofibrillar titin-like Ig domains protein
- Titin immunoglobulin domain protein
Gene names MYOT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UBF9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFNYERPKHF IQSQNPCGSR LQPPGPETSS FSSQTKQSSI IIQPRQCTEQ RFSASSTLSS 
        70         80         90        100        110        120 
HITMSSSAFP ASPKQHAGSN PGQRVTTTYN QSPASFLSSI LPSQPDYNSS KIPSAMDSNY 
       130        140        150        160        170        180 
QQSSAGQPIN AKPSQTANAK PIPRTPDHEI QGSKEALIQD LERKLKCKDT LLHNGNQRLT 
       190        200        210        220        230        240 
YEEKMARRLL GPQNAAAVFQ AQDDSGAQDS QQHNSEHARL QVPTSQVRSR STSRGDVNDQ 
       250        260        270        280        290        300 
DAIQEKFYPP RFIQVPENMS IDEGRFCRMD FKVSGLPAPD VSWYLNGRTV QSDDLHKMIV 
       310        320        330        340        350        360 
SEKGLHSLIF EVVRASDAGA YACVAKNRAG EATFTVQLDV LAKEHKRAPM FIYKPQSKKV 
       370        380        390        400        410        420 
LEGDSVKLEC QISAIPPPKL FWKRNNEMVQ FNTDRISLYQ DNTGRVTLLI KDVNKKDAGW 
       430        440        450        460        470        480 
YTVSAVNEAG VTTCNTRLDV TARPNQTLPA PKQLRVRPTF SKYLALNGKG LNVKQAFNPE 
       490    
GEFQRLAAQS GLYESEEL

Isoforms

- Isoform 2 of Myotilin

Sequence View

        10         20         30         40         50         60 
MFNYERPKHF IQSQNPCGSR LQPPGPETSS FSSQTKQSSI IIQPRQCTEQ RFSASSTLSS 
        70         80         90        100        110        120 
HITMSSSAFP ASPKQHAGSN PGQRVTTTYN QSPASFLSSI LPSQPDYNSS KIPSAMDSNY 
       130        140        150        160        170        180 
QQSSAGQPIN AKPSQTANAK PIPRTPDHEI QGSKEALIQD LERKLKCKDT LLHNGNQRLT 
       190        200        210        220        230        240 
YEEKMARRLL GPQNAAAVFQ AQDDSGAQDS QQHNSEHARL QVPTSQVRSR STSRGDVNDQ 
       250        260        270        280        290        300 
DAIQEKFYPP RFIQVPENMS IDEGRFCRMD FKVSGLPAPD VSWYLNGRTV QSDDLHKMIV 
       310        320        330        340        350        360 
SEKGLHSLIF EVVRASDAGA YACVAKNRAG EATFTVQLDV LAKEHKRAPM FIYKPQSKKV 
       370        380        390        400        410        420 
LEGDSVKLEC QISAIPPPKL FWKRNNEMVQ FNTDRISLYQ DNTGRVTLLI KDVNKKDAGW 
       430        440        450        460        470        480 
YTVSAVNEAG VTTCNTRLDV TARPNQTLPA PKQLRVRPTF SKYLALNGKG LNVKQAFNPE 
       490    
GEFQRLAAQS GLYESEEL



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UBF9-1-unknown MFNYER... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UBF9-185-unknown MARRLL... 185 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82082

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ESEEL 498 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ESEEL 498 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77700

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)