Q9UBM7: 7-dehydrocholesterol reductase

General Information

Protein names	- 7-dehydrocholesterol reductase - 7-DHC reductase - 1.3.1.21 - Putative sterol reductase SR-2 - Sterol Delta(7)-reductase
Gene names	DHCR7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UBM7

3 N-termini

7 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAKSQPNIP KAKSLDGVTN DRTASQGQWG RAWEVDWFSL ASVIFLLLFA PFIVYYFIMA
        70         80         90        100        110        120
CDQYSCALTG PVVDIVTGHA RLSDIWAKTP PITRKAAQLY TLWVTFQVLL YTSLPDFCHK
       130        140        150        160        170        180
FLPGYVGGIQ EGAVTPAGVV NKYQINGLQA WLLTHLLWFA NAHLLSWFSP TIIFDNWIPL
       190        200        210        220        230        240
LWCANILGYA VSTFAMVKGY FFPTSARDCK FTGNFFYNYM MGIEFNPRIG KWFDFKLFFN
       250        260        270        280        290        300
GRPGIVAWTL INLSFAAKQR ELHSHVTNAM VLVNVLQAIY VIDFFWNETW YLKTIDICHD
       310        320        330        340        350        360
HFGWYLGWGD CVWLPYLYTL QGLYLVYHPV QLSTPHAVGV LLLGLVGYYI FRVANHQKDL
       370        380        390        400        410        420
FRRTDGRCLI WGRKPKVIEC SYTSADGQRH HSKLLVSGFW GVARHFNYVG DLMGSLAYCL
       430        440        450        460        470
ACGGGHLLPY FYIIYMAILL THRCLRDEHR CASKYGRDWE RYTAAVPYRL LPGIF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 7 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UBM7-1-unknown	MAAKSQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UBM7-212-unknown	TGNFFY...	212	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435956
Q9UBM7-251-unknown	INLSFA...	251	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435011

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AKTPPI	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000436007
...TPPITR	93	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435058
...TLWVTF	105	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000432589
...VTFQVL	108	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435707
...ANAHLL	164	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435668
...WNETWY	290	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435047
...LPGIF	475	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)