TopFIND 4.0

Q9UBP6: tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}

General Information

Protein names
- tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}
- 2.1.1.33 {ECO:0000255|HAMAP-Rule:MF_03055}
- Methyltransferase-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03055}
- mRNA (guanine-N(7)-)-methyltransferase {ECO:0000305}
- 2.1.1.- {ECO:0000269|PubMed:31031084}
- miRNA (guanine-N(7)-)-methyltransferase {ECO:0000305}
- 2.1.1.- {ECO:0000269|PubMed:31031083}
- tRNA (guanine(46)-N(7))-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}
- tRNA(m7G46)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055}
Gene names METTL1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UBP6

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAETRNVAG AEAPPPQKRY YRQRAHSNPM ADHTLRYPVK PEEMDWSELY PEFFAPLTQN 
        70         80         90        100        110        120 
QSHDDPKDKK EKRAQAQVEF ADIGCGYGGL LVELSPLFPD TLILGLEIRV KVSDYVQDRI 
       130        140        150        160        170        180 
RALRAAPAGG FQNIACLRSN AMKHLPNFFY KGQLTKMFFL FPDPHFKRTK HKWRIISPTL 
       190        200        210        220        230        240 
LAEYAYVLRV GGLVYTITDV LELHDWMCTH FEEHPLFERV PLEDLSEDPV VGHLGTSTEE 
       250        260        270    
GKKVLRNGGK NFPAIFRRIQ DPVLQAVTSQ TSLPGH

Isoforms

- Isoform 2 of tRNA (guanine-N(7)-)-methyltransferase

Sequence View

        10         20         30         40         50         60 
MAAETRNVAG AEAPPPQKRY YRQRAHSNPM ADHTLRYPVK PEEMDWSELY PEFFAPLTQN 
        70         80         90        100        110        120 
QSHDDPKDKK EKRAQAQVEF ADIGCGYGGL LVELSPLFPD TLILGLEIRV KVSDYVQDRI 
       130        140        150        160        170        180 
RALRAAPAGG FQNIACLRSN AMKHLPNFFY KGQLTKMFFL FPDPHFKRTK HKWRIISPTL 
       190        200        210        220        230        240 
LAEYAYVLRV GGLVYTITDV LELHDWMCTH FEEHPLFERV PLEDLSEDPV VGHLGTSTEE 
       250        260        270    
GKKVLRNGGK NFPAIFRRIQ DPVLQAVTSQ TSLPGH



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UBP6-1-unknown MAAETR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93123
    Q9UBP6-2-unknown MAAETR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UBP6-2-Acetylation AAETRN... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UBP6-2-Acetylation AAETRN... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111537

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SLPGH 276 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)