TopFIND 4.0

Q9UD71: Protein phosphatase 1 regulatory subunit 1B

General Information

Protein names
- Protein phosphatase 1 regulatory subunit 1B
- DARPP-32
- Dopamine- and cAMP-regulated neuronal phosphoprotein
Gene names PPP1R1B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UD71

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR LSEHSSPEEE ASPHQRASGE 
        70         80         90        100        110        120 
GHHLKSKRPN PCAYTPPSLK AVQRIAESHL QSISNLNENQ ASEEEDELGE LRELGYPREE 
       130        140        150        160        170        180 
DEEEEEDDEE EEEEEDSQAE VLKVIRQSAG QKTTCGQGLE GPWERPPPLD ESERDGGSED 
       190        200    
QVEDPALSEP GEEPQRPSPS EPGT

Isoforms

- Isoform 2 of Protein phosphatase 1 regulatory subunit 1B

Sequence View

        10         20         30         40         50         60 
MDPKDRKKIQ FSVPAPPSQL DPRQVEMIRR RRPTPAMLFR LSEHSSPEEE ASPHQRASGE 
        70         80         90        100        110        120 
GHHLKSKRPN PCAYTPPSLK AVQRIAESHL QSISNLNENQ ASEEEDELGE LRELGYPREE 
       130        140        150        160        170        180 
DEEEEEDDEE EEEEEDSQAE VLKVIRQSAG QKTTCGQGLE GPWERPPPLD ESERDGGSED 
       190        200    
QVEDPALSEP GEEPQRPSPS EPGT



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UD71-1-Acetylation MDPKDR... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UD71-37-unknown MLFRLS... 37 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86013

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SEPGT 204 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SEPGT 204 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81631

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)