Q9UG01: Intraflagellar transport protein 172 homolog

General Information

Protein names	- Intraflagellar transport protein 172 homolog
Gene names	IFT172
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UG01

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MHLKHLRTLL SPQDGAAKVT CMAWSQNNAK FAVCTVDRVV LLYDEHGERR DKFSTKPADM
        70         80         90        100        110        120
KYGRKSYMVK GMAFSPDSTK IAIGQTDNII YVYKIGEDWG DKKVICNKFI QTSAVTCLQW
       130        140        150        160        170        180
PAEYIIVFGL AEGKVRLANT KTNKSSTIYG TESYVVSLTT NCSGKGILSG HADGTIVRYF
       190        200        210        220        230        240
FDDEGSGESQ GKLVNHPCPP YALAWATNSI VAAGCDRKIV AYGKEGHMLQ TFDYSRDPQE
       250        260        270        280        290        300
REFTTAVSSP GGQSVVLGSY DRLRVFNWIP RRSIWEEAKP KEITNLYTIT ALAWKRDGSR
       310        320        330        340        350        360
LCVGTLCGGV EQFDCCLRRS IYKNKFELTY VGPSQVIVKN LSSGTRVVLK SHYGYEVEEV
       370        380        390        400        410        420
KILGKERYLV AHTSETLLLG DLNTNRLSEI AWQGSGGNEK YFFENENVCM IFNAGELTLV
       430        440        450        460        470        480
EYGNNDTLGS VRTEFMNPHL ISVRINERCQ RGTEDNKKLA YLIDIKTIAI VDLIGGYNIG
       490        500        510        520        530        540
TVSHESRVDW LELNETGHKL LFRDRKLRLH LYDIESCSKT MILNFCSYMQ WVPGSDVLVA
       550        560        570        580        590        600
QNRNSLCVWY NIEAPERVTM FTIRGDVIGL ERGGGKTEVM VMEGVTTVAY TLDEGLIEFG
       610        620        630        640        650        660
TAIDDGNYIR ATAFLETLEM TPETEAMWKT LSKLALEARQ LHIAERCFSA LGQVAKARFL
       670        680        690        700        710        720
HETNEIADQV SREYGGEGTD FYQVRARLAM LEKNYKLAEM IFLEQNAVEE AMGMYQELHR
       730        740        750        760        770        780
WDECIAVAEA KGHPALEKLR RSYYQWLMDT QQEERAGELQ ESQGDGLAAI SLYLKAGLPA
       790        800        810        820        830        840
KAARLVLTRE ELLANTELVE HITAALIKGE LYERAGDLFE KIHNPQKALE CYRKGNAFMK
       850        860        870        880        890        900
AVELARLAFP VEVVKLEEAW GDHLVQQKQL DAAINHYIEA RCSIKAIEAA LGARQWKKAI
       910        920        930        940        950        960
YILDLQDRNT ASKYYPLVAQ HYASLQEYEI AEELYTKGDR TKDAIDMYTQ AGRWEQAHKL
       970        980        990       1000       1010       1020
AMKCMRPEDV SVLYITQAQE MEKQGKYREA ERLYVTVQEP DLAITMYKKH KLYDDMIRLV
      1030       1040       1050       1060       1070       1080
GKHHPDLLSD THLHLGKELE AEGRLQEAEY HYLEAQEWKA TVNMYRASGL WEEAYRVART
      1090       1100       1110       1120       1130       1140
QGGANAHKHV AYLWAKSLGG EAAVRLLNKL GLLEAAVDHA ADNCSFEFAF ELSRLALKHK
      1150       1160       1170       1180       1190       1200
TPEVHLKYAM FLEDEGKFEE AEAEFIRAGK PKEAVLMFVH NQDWEAAQRV AEAHDPDSVA
      1210       1220       1230       1240       1250       1260
EVLVGQARGA LEEKDFQKAE GLLLRAQRPG LALNYYKEAG LWSDALRICK DYVPSQLEAL
      1270       1280       1290       1300       1310       1320
QEEYEREATK KGARGVEGFV EQARHWEQAG EYSRAVDCYL KVRDSGNSGL AEKCWMKAAE
      1330       1340       1350       1360       1370       1380
LSIKFLPPQR NMEVVLAVGP QLIGIGKHSA AAELYLNLDL VKEAIDAFIE GEEWNKAKRV
      1390       1400       1410       1420       1430       1440
AKELDPRYED YVDQHYKEFL KNQGKVDSLV GVDVIAALDL YVEQGQWDKC IETATKQNYK
      1450       1460       1470       1480       1490       1500
ILHKYVALYA THLIREGSSA QALALYVQHG APANPQNFNI YKRIFTDMVS SPGTNCAEAY
      1510       1520       1530       1540       1550       1560
HSWADLRDVL FNLCENLVKS SEANSPAHEE FKTMLLIAHY YATRSAAQSV KQLETVAARL
      1570       1580       1590       1600       1610       1620
SVSLLRHTQL LPVDKAFYEA GIAAKAVGWD NMAFIFLNRF LDLTDAIEEG TLDGLDHSDF
      1630       1640       1650       1660       1670       1680
QDTDIPFEVP LPAKQHVPEA EREEVRDWVL TVSMDQRLEQ VLPRDERGAY EASLVAASTG
      1690       1700       1710       1720       1730       1740
VRALPCLITG YPILRNKIEF KRPGKAANKD NWNKFLMAIK TSHSPVCQDV LKFISQWCGG

LPSTSFSFQ

Isoforms

- Isoform 2 of Intraflagellar transport protein 172 homolog - Isoform 3 of Intraflagellar transport protein 172 homolog

Sequence View

        10         20         30         40         50         60
MHLKHLRTLL SPQDGAAKVT CMAWSQNNAK FAVCTVDRVV LLYDEHGERR DKFSTKPADM
        70         80         90        100        110        120
KYGRKSYMVK GMAFSPDSTK IAIGQTDNII YVYKIGEDWG DKKVICNKFI QTSAVTCLQW
       130        140        150        160        170        180
PAEYIIVFGL AEGKVRLANT KTNKSSTIYG TESYVVSLTT NCSGKGILSG HADGTIVRYF
       190        200        210        220        230        240
FDDEGSGESQ GKLVNHPCPP YALAWATNSI VAAGCDRKIV AYGKEGHMLQ TFDYSRDPQE
       250        260        270        280        290        300
REFTTAVSSP GGQSVVLGSY DRLRVFNWIP RRSIWEEAKP KEITNLYTIT ALAWKRDGSR
       310        320        330        340        350        360
LCVGTLCGGV EQFDCCLRRS IYKNKFELTY VGPSQVIVKN LSSGTRVVLK SHYGYEVEEV
       370        380        390        400        410        420
KILGKERYLV AHTSETLLLG DLNTNRLSEI AWQGSGGNEK YFFENENVCM IFNAGELTLV
       430        440        450        460        470        480
EYGNNDTLGS VRTEFMNPHL ISVRINERCQ RGTEDNKKLA YLIDIKTIAI VDLIGGYNIG
       490        500        510        520        530        540
TVSHESRVDW LELNETGHKL LFRDRKLRLH LYDIESCSKT MILNFCSYMQ WVPGSDVLVA
       550        560        570        580        590        600
QNRNSLCVWY NIEAPERVTM FTIRGDVIGL ERGGGKTEVM VMEGVTTVAY TLDEGLIEFG
       610        620        630        640        650        660
TAIDDGNYIR ATAFLETLEM TPETEAMWKT LSKLALEARQ LHIAERCFSA LGQVAKARFL
       670        680        690        700        710        720
HETNEIADQV SREYGGEGTD FYQVRARLAM LEKNYKLAEM IFLEQNAVEE AMGMYQELHR
       730        740        750        760        770        780
WDECIAVAEA KGHPALEKLR RSYYQWLMDT QQEERAGELQ ESQGDGLAAI SLYLKAGLPA
       790        800        810        820        830        840
KAARLVLTRE ELLANTELVE HITAALIKGE LYERAGDLFE KIHNPQKALE CYRKGNAFMK
       850        860        870        880        890        900
AVELARLAFP VEVVKLEEAW GDHLVQQKQL DAAINHYIEA RCSIKAIEAA LGARQWKKAI
       910        920        930        940        950        960
YILDLQDRNT ASKYYPLVAQ HYASLQEYEI AEELYTKGDR TKDAIDMYTQ AGRWEQAHKL
       970        980        990       1000       1010       1020
AMKCMRPEDV SVLYITQAQE MEKQGKYREA ERLYVTVQEP DLAITMYKKH KLYDDMIRLV
      1030       1040       1050       1060       1070       1080
GKHHPDLLSD THLHLGKELE AEGRLQEAEY HYLEAQEWKA TVNMYRASGL WEEAYRVART
      1090       1100       1110       1120       1130       1140
QGGANAHKHV AYLWAKSLGG EAAVRLLNKL GLLEAAVDHA ADNCSFEFAF ELSRLALKHK
      1150       1160       1170       1180       1190       1200
TPEVHLKYAM FLEDEGKFEE AEAEFIRAGK PKEAVLMFVH NQDWEAAQRV AEAHDPDSVA
      1210       1220       1230       1240       1250       1260
EVLVGQARGA LEEKDFQKAE GLLLRAQRPG LALNYYKEAG LWSDALRICK DYVPSQLEAL
      1270       1280       1290       1300       1310       1320
QEEYEREATK KGARGVEGFV EQARHWEQAG EYSRAVDCYL KVRDSGNSGL AEKCWMKAAE
      1330       1340       1350       1360       1370       1380
LSIKFLPPQR NMEVVLAVGP QLIGIGKHSA AAELYLNLDL VKEAIDAFIE GEEWNKAKRV
      1390       1400       1410       1420       1430       1440
AKELDPRYED YVDQHYKEFL KNQGKVDSLV GVDVIAALDL YVEQGQWDKC IETATKQNYK
      1450       1460       1470       1480       1490       1500
ILHKYVALYA THLIREGSSA QALALYVQHG APANPQNFNI YKRIFTDMVS SPGTNCAEAY
      1510       1520       1530       1540       1550       1560
HSWADLRDVL FNLCENLVKS SEANSPAHEE FKTMLLIAHY YATRSAAQSV KQLETVAARL
      1570       1580       1590       1600       1610       1620
SVSLLRHTQL LPVDKAFYEA GIAAKAVGWD NMAFIFLNRF LDLTDAIEEG TLDGLDHSDF
      1630       1640       1650       1660       1670       1680
QDTDIPFEVP LPAKQHVPEA EREEVRDWVL TVSMDQRLEQ VLPRDERGAY EASLVAASTG
      1690       1700       1710       1720       1730       1740
VRALPCLITG YPILRNKIEF KRPGKAANKD NWNKFLMAIK TSHSPVCQDV LKFISQWCGG

LPSTSFSFQ         10         20         30         40         50         60
MHLKHLRTLL SPQDGAAKVT CMAWSQNNAK FAVCTVDRVV LLYDEHGERR DKFSTKPADM
        70         80         90        100        110        120
KYGRKSYMVK GMAFSPDSTK IAIGQTDNII YVYKIGEDWG DKKVICNKFI QTSAVTCLQW
       130        140        150        160        170        180
PAEYIIVFGL AEGKVRLANT KTNKSSTIYG TESYVVSLTT NCSGKGILSG HADGTIVRYF
       190        200        210        220        230        240
FDDEGSGESQ GKLVNHPCPP YALAWATNSI VAAGCDRKIV AYGKEGHMLQ TFDYSRDPQE
       250        260        270        280        290        300
REFTTAVSSP GGQSVVLGSY DRLRVFNWIP RRSIWEEAKP KEITNLYTIT ALAWKRDGSR
       310        320        330        340        350        360
LCVGTLCGGV EQFDCCLRRS IYKNKFELTY VGPSQVIVKN LSSGTRVVLK SHYGYEVEEV
       370        380        390        400        410        420
KILGKERYLV AHTSETLLLG DLNTNRLSEI AWQGSGGNEK YFFENENVCM IFNAGELTLV
       430        440        450        460        470        480
EYGNNDTLGS VRTEFMNPHL ISVRINERCQ RGTEDNKKLA YLIDIKTIAI VDLIGGYNIG
       490        500        510        520        530        540
TVSHESRVDW LELNETGHKL LFRDRKLRLH LYDIESCSKT MILNFCSYMQ WVPGSDVLVA
       550        560        570        580        590        600
QNRNSLCVWY NIEAPERVTM FTIRGDVIGL ERGGGKTEVM VMEGVTTVAY TLDEGLIEFG
       610        620        630        640        650        660
TAIDDGNYIR ATAFLETLEM TPETEAMWKT LSKLALEARQ LHIAERCFSA LGQVAKARFL
       670        680        690        700        710        720
HETNEIADQV SREYGGEGTD FYQVRARLAM LEKNYKLAEM IFLEQNAVEE AMGMYQELHR
       730        740        750        760        770        780
WDECIAVAEA KGHPALEKLR RSYYQWLMDT QQEERAGELQ ESQGDGLAAI SLYLKAGLPA
       790        800        810        820        830        840
KAARLVLTRE ELLANTELVE HITAALIKGE LYERAGDLFE KIHNPQKALE CYRKGNAFMK
       850        860        870        880        890        900
AVELARLAFP VEVVKLEEAW GDHLVQQKQL DAAINHYIEA RCSIKAIEAA LGARQWKKAI
       910        920        930        940        950        960
YILDLQDRNT ASKYYPLVAQ HYASLQEYEI AEELYTKGDR TKDAIDMYTQ AGRWEQAHKL
       970        980        990       1000       1010       1020
AMKCMRPEDV SVLYITQAQE MEKQGKYREA ERLYVTVQEP DLAITMYKKH KLYDDMIRLV
      1030       1040       1050       1060       1070       1080
GKHHPDLLSD THLHLGKELE AEGRLQEAEY HYLEAQEWKA TVNMYRASGL WEEAYRVART
      1090       1100       1110       1120       1130       1140
QGGANAHKHV AYLWAKSLGG EAAVRLLNKL GLLEAAVDHA ADNCSFEFAF ELSRLALKHK
      1150       1160       1170       1180       1190       1200
TPEVHLKYAM FLEDEGKFEE AEAEFIRAGK PKEAVLMFVH NQDWEAAQRV AEAHDPDSVA
      1210       1220       1230       1240       1250       1260
EVLVGQARGA LEEKDFQKAE GLLLRAQRPG LALNYYKEAG LWSDALRICK DYVPSQLEAL
      1270       1280       1290       1300       1310       1320
QEEYEREATK KGARGVEGFV EQARHWEQAG EYSRAVDCYL KVRDSGNSGL AEKCWMKAAE
      1330       1340       1350       1360       1370       1380
LSIKFLPPQR NMEVVLAVGP QLIGIGKHSA AAELYLNLDL VKEAIDAFIE GEEWNKAKRV
      1390       1400       1410       1420       1430       1440
AKELDPRYED YVDQHYKEFL KNQGKVDSLV GVDVIAALDL YVEQGQWDKC IETATKQNYK
      1450       1460       1470       1480       1490       1500
ILHKYVALYA THLIREGSSA QALALYVQHG APANPQNFNI YKRIFTDMVS SPGTNCAEAY
      1510       1520       1530       1540       1550       1560
HSWADLRDVL FNLCENLVKS SEANSPAHEE FKTMLLIAHY YATRSAAQSV KQLETVAARL
      1570       1580       1590       1600       1610       1620
SVSLLRHTQL LPVDKAFYEA GIAAKAVGWD NMAFIFLNRF LDLTDAIEEG TLDGLDHSDF
      1630       1640       1650       1660       1670       1680
QDTDIPFEVP LPAKQHVPEA EREEVRDWVL TVSMDQRLEQ VLPRDERGAY EASLVAASTG
      1690       1700       1710       1720       1730       1740
VRALPCLITG YPILRNKIEF KRPGKAANKD NWNKFLMAIK TSHSPVCQDV LKFISQWCGG

LPSTSFSFQ

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9UG01-1-unknown	MHLKHL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77525
Q9UG01-1-unknown	MHLKHL...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt77526
Q9UG01-1-Acetylation	MHLKHL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UG01-1-Acetylation	MHLKHL...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106095
Q9UG01-1-Acetylation	MHLKHL...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt106096
Q9UG01-22-unknown	MAWSQN...	22		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000407408
Q9UG01-22-unknown	MAWSQN...	22		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195272
Q9UG01-22-unknown	MAWSQN...	22		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195273

TopFIND

Q9UG01: Intraflagellar transport protein 172 homolog

General Information

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates