TopFIND 4.0

Q9UGJ0: 5'-AMP-activated protein kinase subunit gamma-2

General Information

Protein names
- 5'-AMP-activated protein kinase subunit gamma-2
- AMPK gamma2
- AMPK subunit gamma-2
- H91620p
Gene names PRKAG2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UGJ0

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGSAVMDTKK KKDVSSPGGS GGKKNASQKR RSLRVHIPDL SSFAMPLLDG DLEGSGKHSS 
        70         80         90        100        110        120 
RKVDSPFGPG SPSKGFFSRG PQPRPSSPMS APVRPKTSPG SPKTVFPFSY QESPPRSPRR 
       130        140        150        160        170        180 
MSFSGIFRSS SKESSPNSNP ATSPGGIRFF SRSRKTSGLS SSPSTPTQVT KQHTFPLESY 
       190        200        210        220        230        240 
KHEPERLENR IYASSSPPDT GQRFCPSSFQ SPTRPPLASP THYAPSKAAA LAAALGPAEA 
       250        260        270        280        290        300 
GMLEKLEFED EAVEDSESGV YMRFMRSHKC YDIVPTSSKL VVFDTTLQVK KAFFALVANG 
       310        320        330        340        350        360 
VRAAPLWESK KQSFVGMLTI TDFINILHRY YKSPMVQIYE LEEHKIETWR ELYLQETFKP 
       370        380        390        400        410        420 
LVNISPDASL FDAVYSLIKN KIHRLPVIDP ISGNALYILT HKRILKFLQL FMSDMPKPAF 
       430        440        450        460        470        480 
MKQNLDELGI GTYHNIAFIH PDTPIIKALN IFVERRISAL PVVDESGKVV DIYSKFDVIN 
       490        500        510        520        530        540 
LAAEKTYNNL DITVTQALQH RSQYFEGVVK CNKLEILETI VDRIVRAEVH RLVVVNEADS 
       550        560    
IVGIISLSDI LQALILTPAG AKQKETETE

Isoforms

- Isoform B of 5'-AMP-activated protein kinase subunit gamma-2 - Isoform C of 5'-AMP-activated protein kinase subunit gamma-2

Sequence View

        10         20         30         40         50         60 
MGSAVMDTKK KKDVSSPGGS GGKKNASQKR RSLRVHIPDL SSFAMPLLDG DLEGSGKHSS 
        70         80         90        100        110        120 
RKVDSPFGPG SPSKGFFSRG PQPRPSSPMS APVRPKTSPG SPKTVFPFSY QESPPRSPRR 
       130        140        150        160        170        180 
MSFSGIFRSS SKESSPNSNP ATSPGGIRFF SRSRKTSGLS SSPSTPTQVT KQHTFPLESY 
       190        200        210        220        230        240 
KHEPERLENR IYASSSPPDT GQRFCPSSFQ SPTRPPLASP THYAPSKAAA LAAALGPAEA 
       250        260        270        280        290        300 
GMLEKLEFED EAVEDSESGV YMRFMRSHKC YDIVPTSSKL VVFDTTLQVK KAFFALVANG 
       310        320        330        340        350        360 
VRAAPLWESK KQSFVGMLTI TDFINILHRY YKSPMVQIYE LEEHKIETWR ELYLQETFKP 
       370        380        390        400        410        420 
LVNISPDASL FDAVYSLIKN KIHRLPVIDP ISGNALYILT HKRILKFLQL FMSDMPKPAF 
       430        440        450        460        470        480 
MKQNLDELGI GTYHNIAFIH PDTPIIKALN IFVERRISAL PVVDESGKVV DIYSKFDVIN 
       490        500        510        520        530        540 
LAAEKTYNNL DITVTQALQH RSQYFEGVVK CNKLEILETI VDRIVRAEVH RLVVVNEADS 
       550        560    
IVGIISLSDI LQALILTPAG AKQKETETE         10         20         30         40         50         60 
MGSAVMDTKK KKDVSSPGGS GGKKNASQKR RSLRVHIPDL SSFAMPLLDG DLEGSGKHSS 
        70         80         90        100        110        120 
RKVDSPFGPG SPSKGFFSRG PQPRPSSPMS APVRPKTSPG SPKTVFPFSY QESPPRSPRR 
       130        140        150        160        170        180 
MSFSGIFRSS SKESSPNSNP ATSPGGIRFF SRSRKTSGLS SSPSTPTQVT KQHTFPLESY 
       190        200        210        220        230        240 
KHEPERLENR IYASSSPPDT GQRFCPSSFQ SPTRPPLASP THYAPSKAAA LAAALGPAEA 
       250        260        270        280        290        300 
GMLEKLEFED EAVEDSESGV YMRFMRSHKC YDIVPTSSKL VVFDTTLQVK KAFFALVANG 
       310        320        330        340        350        360 
VRAAPLWESK KQSFVGMLTI TDFINILHRY YKSPMVQIYE LEEHKIETWR ELYLQETFKP 
       370        380        390        400        410        420 
LVNISPDASL FDAVYSLIKN KIHRLPVIDP ISGNALYILT HKRILKFLQL FMSDMPKPAF 
       430        440        450        460        470        480 
MKQNLDELGI GTYHNIAFIH PDTPIIKALN IFVERRISAL PVVDESGKVV DIYSKFDVIN 
       490        500        510        520        530        540 
LAAEKTYNNL DITVTQALQH RSQYFEGVVK CNKLEILETI VDRIVRAEVH RLVVVNEADS 
       550        560    
IVGIISLSDI LQALILTPAG AKQKETETE



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UGJ0-1-unknown MGSAVM... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UGJ0-45-unknown MPLLDG... 45 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65891
    Q9UGJ0-242-unknown MLEKLE... 242 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65890
    Q9UGJ0-242-unknown MLEKLE... 242 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101434

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)