TopFIND 4.0

Q9UGK8: Secretion-regulating guanine nucleotide exchange factor

General Information

Protein names
- Secretion-regulating guanine nucleotide exchange factor
- Deafness locus-associated putative guanine nucleotide exchange factor
- DelGEF
- Guanine nucleotide exchange factor-related protein
Gene names SERGEF
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UGK8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEREPSASEA APAAAALFAW GANSYGQLGL GHKEDVLLPQ QLNDFCKPRS VRRITGGGGH 
        70         80         90        100        110        120 
SAVVTDGGDL FVCGLNKDGQ LGLGHTEDIP YFTPCKSLFG CPIQQVACGW DFTIMLTENG 
       130        140        150        160        170        180 
QVLSCGSNSF GQLGVPHGPR RCVVPQAIEL HKEKVVCIAA GLRHAVAATA SGIVFQWGTG 
       190        200        210        220        230        240 
LASCGRRLCP GQTLPLFFTA KEPSRVTGLE NSKAMCVLAG SDHSASLTDA GEVYVWGSNK 
       250        260        270        280        290        300 
HGQLANEAAF LPVPQKIEAH CFQNEKVTAI WSGWTHLVAQ TETGKMFTWG RADYGQLGRK 
       310        320        330        340        350        360 
LETYEGWKLE KQDSFLPCSR PPNSMPSSPH CLTGATEVSC GSEHNLAIIG GVCYSWGWNE 
       370        380        390        400        410        420 
HGMCGDGTEA NVWAPKPVQA LLSSSGLLVG CGAGHSLALC QLPAHPALVQ DPKVTYLSPD 
       430        440        450    
AIEDTESQKA MDKERNWKER QSETSTQSQS DWSRNGGL

Isoforms

- Isoform 2 of Secretion-regulating guanine nucleotide exchange factor

Sequence View

        10         20         30         40         50         60 
MEREPSASEA APAAAALFAW GANSYGQLGL GHKEDVLLPQ QLNDFCKPRS VRRITGGGGH 
        70         80         90        100        110        120 
SAVVTDGGDL FVCGLNKDGQ LGLGHTEDIP YFTPCKSLFG CPIQQVACGW DFTIMLTENG 
       130        140        150        160        170        180 
QVLSCGSNSF GQLGVPHGPR RCVVPQAIEL HKEKVVCIAA GLRHAVAATA SGIVFQWGTG 
       190        200        210        220        230        240 
LASCGRRLCP GQTLPLFFTA KEPSRVTGLE NSKAMCVLAG SDHSASLTDA GEVYVWGSNK 
       250        260        270        280        290        300 
HGQLANEAAF LPVPQKIEAH CFQNEKVTAI WSGWTHLVAQ TETGKMFTWG RADYGQLGRK 
       310        320        330        340        350        360 
LETYEGWKLE KQDSFLPCSR PPNSMPSSPH CLTGATEVSC GSEHNLAIIG GVCYSWGWNE 
       370        380        390        400        410        420 
HGMCGDGTEA NVWAPKPVQA LLSSSGLLVG CGAGHSLALC QLPAHPALVQ DPKVTYLSPD 
       430        440        450    
AIEDTESQKA MDKERNWKER QSETSTQSQS DWSRNGGL



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UGK8-1-unknown MEREPS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UGK8-1-unknown MEREPS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90677

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RNGGL 458 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)