TopFIND 4.0

Q9UH17: DNA dC->dU-editing enzyme APOBEC-3B

General Information

Protein names
- DNA dC->dU-editing enzyme APOBEC-3B
- A3B
- 3.5.4.38
- Phorbolin-1-related protein
- Phorbolin-2/3
Gene names APOBEC3B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UH17

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGQVY 
        70         80         90        100        110        120 
FKPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC VAKLAEFLSE HPNVTLTISA 
       130        140        150        160        170        180 
ARLYYYWERD YRRALCRLSQ AGARVTIMDY EEFAYCWENF VYNEGQQFMP WYKFDENYAF 
       190        200        210        220        230        240 
LHRTLKEILR YLMDPDTFTF NFNNDPLVLR RRQTYLCYEV ERLDNGTWVL MDQHMGFLCN 
       250        260        270        280        290        300 
EAKNLLCGFY GRHAELRFLD LVPSLQLDPA QIYRVTWFIS WSPCFSWGCA GEVRAFLQEN 
       310        320        330        340        350        360 
THVRLRIFAA RIYDYDPLYK EALQMLRDAG AQVSIMTYDE FEYCWDTFVY RQGCPFQPWD 
       370        380    
GLEEHSQALS GRLRAILQNQ GN

Isoforms

- Isoform 2 of DNA dC->dU-editing enzyme APOBEC-3B - Isoform 3 of DNA dC->dU-editing enzyme APOBEC-3B

Sequence View

        10         20         30         40         50         60 
MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGQVY 
        70         80         90        100        110        120 
FKPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC VAKLAEFLSE HPNVTLTISA 
       130        140        150        160        170        180 
ARLYYYWERD YRRALCRLSQ AGARVTIMDY EEFAYCWENF VYNEGQQFMP WYKFDENYAF 
       190        200        210        220        230        240 
LHRTLKEILR YLMDPDTFTF NFNNDPLVLR RRQTYLCYEV ERLDNGTWVL MDQHMGFLCN 
       250        260        270        280        290        300 
EAKNLLCGFY GRHAELRFLD LVPSLQLDPA QIYRVTWFIS WSPCFSWGCA GEVRAFLQEN 
       310        320        330        340        350        360 
THVRLRIFAA RIYDYDPLYK EALQMLRDAG AQVSIMTYDE FEYCWDTFVY RQGCPFQPWD 
       370        380    
GLEEHSQALS GRLRAILQNQ GN         10         20         30         40         50         60 
MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW DTGVFRGQVY 
        70         80         90        100        110        120 
FKPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC VAKLAEFLSE HPNVTLTISA 
       130        140        150        160        170        180 
ARLYYYWERD YRRALCRLSQ AGARVTIMDY EEFAYCWENF VYNEGQQFMP WYKFDENYAF 
       190        200        210        220        230        240 
LHRTLKEILR YLMDPDTFTF NFNNDPLVLR RRQTYLCYEV ERLDNGTWVL MDQHMGFLCN 
       250        260        270        280        290        300 
EAKNLLCGFY GRHAELRFLD LVPSLQLDPA QIYRVTWFIS WSPCFSWGCA GEVRAFLQEN 
       310        320        330        340        350        360 
THVRLRIFAA RIYDYDPLYK EALQMLRDAG AQVSIMTYDE FEYCWDTFVY RQGCPFQPWD 
       370        380    
GLEEHSQALS GRLRAILQNQ GN



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Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UH17-1-unknown MNPQIR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UH17-1-unknown MNPQIR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65927
    Q9UH17-1-unknown MNPQIR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt65928

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QNQGN 382 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QNQGN 382 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61546

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)