Q9UHB4: NADPH-dependent diflavin oxidoreductase 1 {ECO:0000255|HAMAP-Rule:MF_03178}

General Information

Protein names	- NADPH-dependent diflavin oxidoreductase 1 {ECO:0000255\|HAMAP-Rule:MF_03178} - 1.18.1.- {ECO:0000255\|HAMAP-Rule:MF_03178} - NADPH-dependent FMN and FAD-containing oxidoreductase {ECO:0000255\|HAMAP-Rule:MF_03178} - Novel reductase 1
Gene names	NDOR1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHB4

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of NADPH-dependent diflavin oxidoreductase 1 - Isoform 3 of NADPH-dependent diflavin oxidoreductase 1 - Isoform 4 of NADPH-dependent diflavin oxidoreductase 1

Sequence View

        10         20         30         40         50         60
MPSPQLLVLF GSQTGTAQDV SERLGREARR RRLGCRVQAL DSYPVVNLIN EPLVIFVCAT
        70         80         90        100        110        120
TGQGDPPDNM KNFWRFIFRK NLPSTALCQM DFAVLGLGDS SYAKFNFVAK KLHRRLLQLG
       130        140        150        160        170        180
GSALLPVCLG DDQHELGPDA AVDPWLRDLW DRVLGLYPPP PGLTEIPPGV PLPSKFTLLF
       190        200        210        220        230        240
LQEAPSTGSE GQRVAHPGSQ EPPSESKPFL APMISNQRVT GPSHFQDVRL IEFDILGSGI
       250        260        270        280        290        300
SFAAGDVVLI QPSNSAAHVQ RFCQVLGLDP DQLFMLQPRE PDVSSPTRLP QPCSMRHLVS
       310        320        330        340        350        360
HYLDIASVPR RSFFELLACL SLHELEREKL LEFSSAQGQE ELFEYCNRPR RTILEVLCDF
       370        380        390        400        410        420
PHTAAAIPPD YLLDLIPVIR PRAFSIASSL LTHPSRLQIL VAVVQFQTRL KEPRRGLCSS
       430        440        450        460        470        480
WLASLDPGQG PVRVPLWVRP GSLAFPETPD TPVIMVGPGT GVAPFRAAIQ ERVAQGQTGN
       490        500        510        520        530        540
FLFFGCRWRD QDFYWEAEWQ ELEKRDCLTL IPAFSREQEQ KVYVQHRLRE LGSLVWELLD
       550        560        570        580        590
RQGAYFYLAG NAKSMPADVS EALMSIFQEE GGLCSPDAAA YLARLQQTRR FQTETWA         10         20         30         40         50         60
MPSPQLLVLF GSQTGTAQDV SERLGREARR RRLGCRVQAL DSYPVVNLIN EPLVIFVCAT
        70         80         90        100        110        120
TGQGDPPDNM KNFWRFIFRK NLPSTALCQM DFAVLGLGDS SYAKFNFVAK KLHRRLLQLG
       130        140        150        160        170        180
GSALLPVCLG DDQHELGPDA AVDPWLRDLW DRVLGLYPPP PGLTEIPPGV PLPSKFTLLF
       190        200        210        220        230        240
LQEAPSTGSE GQRVAHPGSQ EPPSESKPFL APMISNQRVT GPSHFQDVRL IEFDILGSGI
       250        260        270        280        290        300
SFAAGDVVLI QPSNSAAHVQ RFCQVLGLDP DQLFMLQPRE PDVSSPTRLP QPCSMRHLVS
       310        320        330        340        350        360
HYLDIASVPR RSFFELLACL SLHELEREKL LEFSSAQGQE ELFEYCNRPR RTILEVLCDF
       370        380        390        400        410        420
PHTAAAIPPD YLLDLIPVIR PRAFSIASSL LTHPSRLQIL VAVVQFQTRL KEPRRGLCSS
       430        440        450        460        470        480
WLASLDPGQG PVRVPLWVRP GSLAFPETPD TPVIMVGPGT GVAPFRAAIQ ERVAQGQTGN
       490        500        510        520        530        540
FLFFGCRWRD QDFYWEAEWQ ELEKRDCLTL IPAFSREQEQ KVYVQHRLRE LGSLVWELLD
       550        560        570        580        590
RQGAYFYLAG NAKSMPADVS EALMSIFQEE GGLCSPDAAA YLARLQQTRR FQTETWA         10         20         30         40         50         60
MPSPQLLVLF GSQTGTAQDV SERLGREARR RRLGCRVQAL DSYPVVNLIN EPLVIFVCAT
        70         80         90        100        110        120
TGQGDPPDNM KNFWRFIFRK NLPSTALCQM DFAVLGLGDS SYAKFNFVAK KLHRRLLQLG
       130        140        150        160        170        180
GSALLPVCLG DDQHELGPDA AVDPWLRDLW DRVLGLYPPP PGLTEIPPGV PLPSKFTLLF
       190        200        210        220        230        240
LQEAPSTGSE GQRVAHPGSQ EPPSESKPFL APMISNQRVT GPSHFQDVRL IEFDILGSGI
       250        260        270        280        290        300
SFAAGDVVLI QPSNSAAHVQ RFCQVLGLDP DQLFMLQPRE PDVSSPTRLP QPCSMRHLVS
       310        320        330        340        350        360
HYLDIASVPR RSFFELLACL SLHELEREKL LEFSSAQGQE ELFEYCNRPR RTILEVLCDF
       370        380        390        400        410        420
PHTAAAIPPD YLLDLIPVIR PRAFSIASSL LTHPSRLQIL VAVVQFQTRL KEPRRGLCSS
       430        440        450        460        470        480
WLASLDPGQG PVRVPLWVRP GSLAFPETPD TPVIMVGPGT GVAPFRAAIQ ERVAQGQTGN
       490        500        510        520        530        540
FLFFGCRWRD QDFYWEAEWQ ELEKRDCLTL IPAFSREQEQ KVYVQHRLRE LGSLVWELLD
       550        560        570        580        590
RQGAYFYLAG NAKSMPADVS EALMSIFQEE GGLCSPDAAA YLARLQQTRR FQTETWA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UHB4-1-unknown	MPSPQL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHB4-1-unknown	MPSPQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82472
Q9UHB4-1-unknown	MPSPQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82473
Q9UHB4-1-unknown	MPSPQL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt82474
Q9UHB4-2-unknown	PSPQLL...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UHB4-2-unknown	PSPQLL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178898
Q9UHB4-2-unknown	PSPQLL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178899
Q9UHB4-2-unknown	PSPQLL...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt178900

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TETWA	597	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TETWA	597	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt78092
...TETWA	597	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt78090

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)