Q9UHG3: Prenylcysteine oxidase 1

General Information

Protein names	- Prenylcysteine oxidase 1 - 1.8.3.5 - Prenylcysteine lyase
Gene names	PCYOX1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UHG3

6 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGRVVAELVS SLLGLWLLLC SCGCPEGAEL RAPPDKIAII GAGIGGTSAA YYLRQKFGKD
        70         80         90        100        110        120
VKIDLFEREE VGGRLATMMV QGQEYEAGGS VIHPLNLHMK RFVKDLGLSA VQASGGLLGI
       130        140        150        160        170        180
YNGETLVFEE SNWFIINVIK LVWRYGFQSL RMHMWVEDVL DKFMRIYRYQ SHDYAFSSVE
       190        200        210        220        230        240
KLLHALGGDD FLGMLNRTLL ETLQKAGFSE KFLNEMIAPV MRVNYGQSTD INAFVGAVSL
       250        260        270        280        290        300
SCSDSGLWAV EGGNKLVCSG LLQASKSNLI SGSVMYIEEK TKTKYTGNPT KMYEVVYQIG
       310        320        330        340        350        360
TETRSDFYDI VLVATPLNRK MSNITFLNFD PPIEEFHQYY QHIVTTLVKG ELNTSIFSSR
       370        380        390        400        410        420
PIDKFGLNTV LTTDNSDLFI NSIGIVPSVR EKEDPEPSTD GTYVWKIFSQ ETLTKAQILK
       430        440        450        460        470        480
LFLSYDYAVK KPWLAYPHYK PPEKCPSIIL HDRLYYLNGI ECAASAMEMS AIAAHNAALL
       490        500
AYHRWNGHTD MIDQDGLYEK LKTEL

Isoforms

- Isoform 2 of Prenylcysteine oxidase 1

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UHG3-23-unknown	GCPEGA...	23		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099
Q9UHG3-28-unknown	AELRAP...	28	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UHG3-28-	AELRAP...	28		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9UHG3-78-unknown	MMVQGQ...	78	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000404327
Q9UHG3-78-unknown	MMVQGQ...	78	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000413178
Q9UHG3-78-unknown	MMVQGQ...	78	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000408751
Q9UHG3-78-unknown	MMVQGQ...	78	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000441566
Q9UHG3-79-unknown	MVQGQE...	79	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000439916
Q9UHG3-269-unknown	LISGSV...	269		unknown			Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TLQKAG	206	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404327
...QSTDIN	231	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408751
...KTKYTG	286	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000413178
...LKTEL	505	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)