TopFIND 4.0

Q9UJA5: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6

General Information

Protein names
- tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
- mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6 {ECO:0000303|PubMed:29072297}
- tRNA(m1A58)-methyltransferase subunit TRM6
- tRNA(m1A58)MTase subunit TRM6
Gene names TRMT6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UJA5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ WFYLDNVIGH 
        70         80         90        100        110        120 
SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD GKSQKLTQDD IKALKDKGIK 
       130        140        150        160        170        180 
GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK KKKYEAIITV VKPSTRILSI MYYAREPGKI 
       190        200        210        220        230        240 
NHMRYDTLAQ MLTLGNIRAG NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA 
       250        260        270        280        290        300 
TACFGFPKSF LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ 
       310        320        330        340        350        360 
ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ EEQRKRHLEA 
       370        380        390        400        410        420 
AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV 
       430        440        450        460        470        480 
INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVA MDNLKADTSL KSNASTLESH 
       490    
ETEEPAAKKR KCPESDS

Isoforms

- Isoform 2 of tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 - Isoform 3 of tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 - Isoform 4 of tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6

Sequence View

        10         20         30         40         50         60 
MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ WFYLDNVIGH 
        70         80         90        100        110        120 
SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD GKSQKLTQDD IKALKDKGIK 
       130        140        150        160        170        180 
GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK KKKYEAIITV VKPSTRILSI MYYAREPGKI 
       190        200        210        220        230        240 
NHMRYDTLAQ MLTLGNIRAG NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA 
       250        260        270        280        290        300 
TACFGFPKSF LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ 
       310        320        330        340        350        360 
ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ EEQRKRHLEA 
       370        380        390        400        410        420 
AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV 
       430        440        450        460        470        480 
INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVA MDNLKADTSL KSNASTLESH 
       490    
ETEEPAAKKR KCPESDS         10         20         30         40         50         60 
MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ WFYLDNVIGH 
        70         80         90        100        110        120 
SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD GKSQKLTQDD IKALKDKGIK 
       130        140        150        160        170        180 
GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK KKKYEAIITV VKPSTRILSI MYYAREPGKI 
       190        200        210        220        230        240 
NHMRYDTLAQ MLTLGNIRAG NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA 
       250        260        270        280        290        300 
TACFGFPKSF LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ 
       310        320        330        340        350        360 
ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ EEQRKRHLEA 
       370        380        390        400        410        420 
AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV 
       430        440        450        460        470        480 
INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVA MDNLKADTSL KSNASTLESH 
       490    
ETEEPAAKKR KCPESDS         10         20         30         40         50         60 
MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ WFYLDNVIGH 
        70         80         90        100        110        120 
SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD GKSQKLTQDD IKALKDKGIK 
       130        140        150        160        170        180 
GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK KKKYEAIITV VKPSTRILSI MYYAREPGKI 
       190        200        210        220        230        240 
NHMRYDTLAQ MLTLGNIRAG NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA 
       250        260        270        280        290        300 
TACFGFPKSF LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ 
       310        320        330        340        350        360 
ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ EEQRKRHLEA 
       370        380        390        400        410        420 
AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY CQYKEPLLEC YTKLRERGGV 
       430        440        450        460        470        480 
INLRLSETWL RNYQVLPDRS HPKLLMSGGG GYLLSGFTVA MDNLKADTSL KSNASTLESH 
       490    
ETEEPAAKKR KCPESDS



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PESDS 497 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PESDS 497 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt88737

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)