Q9UJX2: Cell division cycle protein 23 homolog

General Information

Protein names	- Cell division cycle protein 23 homolog - Anaphase-promoting complex subunit 8 - APC8 - Cyclosome subunit 8
Gene names	CDC23
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UJX2

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cell division cycle protein 23 homolog - Isoform 3 of Cell division cycle protein 23 homolog

Sequence View

        10         20         30         40         50         60
MAASTSMVPV AVTAAVAPVL SINSDFSDLR EIKKQLLLIA GLTRERGLLH SSKWSAELAF
        70         80         90        100        110        120
SLPALPLAEL QPPPPITEED AQDMDAYTLA KAYFDVKEYD RAAHFLHGCN SKKAYFLYMY
       130        140        150        160        170        180
SRYLSGEKKK DDETVDSLGP LEKGQVKNEA LRELRVELSK KHQARELDGF GLYLYGVVLR
       190        200        210        220        230        240
KLDLVKEAID VFVEATHVLP LHWGAWLELC NLITDKEMLK FLSLPDTWMK EFFLAHIYTE
       250        260        270        280        290        300
LQLIEEALQK YQNLIDVGFS KSSYIVSQIA VAYHNIRDID KALSIFNELR KQDPYRIENM
       310        320        330        340        350        360
DTFSNLLYVR SMKSELSYLA HNLCEIDKYR VETCCVIGNY YSLRSQHEKA ALYFQRALKL
       370        380        390        400        410        420
NPRYLGAWTL MGHEYMEMKN TSAAIQAYRH AIEVNKRDYR AWYGLGQTYE ILKMPFYCLY
       430        440        450        460        470        480
YYRRAHQLRP NDSRMLVALG ECYEKLNQLV EAKKCYWRAY AVGDVEKMAL VKLAKLHEQL
       490        500        510        520        530        540
TESEQAAQCY IKYIQDIYSC GEIVEHLEES TAFRYLAQYY FKCKLWDEAS TCAQKCCAFN
       550        560        570        580        590
DTREEGKALL RQILQLRNQG ETPTTEVPAP FFLPASLSAN NTPTRRVSPL NLSSVTP         10         20         30         40         50         60
MAASTSMVPV AVTAAVAPVL SINSDFSDLR EIKKQLLLIA GLTRERGLLH SSKWSAELAF
        70         80         90        100        110        120
SLPALPLAEL QPPPPITEED AQDMDAYTLA KAYFDVKEYD RAAHFLHGCN SKKAYFLYMY
       130        140        150        160        170        180
SRYLSGEKKK DDETVDSLGP LEKGQVKNEA LRELRVELSK KHQARELDGF GLYLYGVVLR
       190        200        210        220        230        240
KLDLVKEAID VFVEATHVLP LHWGAWLELC NLITDKEMLK FLSLPDTWMK EFFLAHIYTE
       250        260        270        280        290        300
LQLIEEALQK YQNLIDVGFS KSSYIVSQIA VAYHNIRDID KALSIFNELR KQDPYRIENM
       310        320        330        340        350        360
DTFSNLLYVR SMKSELSYLA HNLCEIDKYR VETCCVIGNY YSLRSQHEKA ALYFQRALKL
       370        380        390        400        410        420
NPRYLGAWTL MGHEYMEMKN TSAAIQAYRH AIEVNKRDYR AWYGLGQTYE ILKMPFYCLY
       430        440        450        460        470        480
YYRRAHQLRP NDSRMLVALG ECYEKLNQLV EAKKCYWRAY AVGDVEKMAL VKLAKLHEQL
       490        500        510        520        530        540
TESEQAAQCY IKYIQDIYSC GEIVEHLEES TAFRYLAQYY FKCKLWDEAS TCAQKCCAFN
       550        560        570        580        590
DTREEGKALL RQILQLRNQG ETPTTEVPAP FFLPASLSAN NTPTRRVSPL NLSSVTP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q9UJX2-1-unknown	MAASTS...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70040
Q9UJX2-2-unknown	MAASTS...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UJX2-2-Acetylation	AASTSM...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UJX2-2-Acetylation	AASTSM...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt111179
Q9UJX2-119-unknown	MYSRYL...	119		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt70041

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VSPLNL	591		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...VSPLNL	591		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...VSPLNL	591		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...VSPLNL	591		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...VSPLNL	591	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt143123
...SSVTP	597	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SSVTP	597	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt65659

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)