TopFIND 4.0

Q9UKK3: Protein mono-ADP-ribosyltransferase PARP4 {ECO:0000305}

General Information

Protein names
- Protein mono-ADP-ribosyltransferase PARP4 {ECO:0000305}
- 2.4.2.- {ECO:0000269|PubMed:25043379}
- 193 kDa vault protein {ECO:0000303|PubMed:10477748}
- ADP-ribosyltransferase diphtheria toxin-like 4 {ECO:0000303|PubMed:20106667}
- ARTD4 {ECO:0000303|PubMed:20106667}
- PARP-related/IalphaI-related H5/proline-rich {ECO:0000303|PubMed:10100603}
- PH5P {ECO:0000303|PubMed:10100603}
- Poly ADP-ribose] polymerase 4 {ECO:0000303|PubMed:20106667}
- PARP-4 {ECO:0000303|PubMed:20106667}
- Vault poly(ADP-ribose) polymerase {ECO:0000303|PubMed:10477748}
- VPARP {ECO:0000303|PubMed:10477748}
Gene names PARP4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UKK3

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVMGIFANCI FCLKVKYLPQ QQKKKLQTDI KENGGKFSFS LNPQCTHIIL DNADVLSQYQ 
        70         80         90        100        110        120 
LNSIQKNHVH IANPDFIWKS IREKRLLDVK NYDPYKPLDI TPPPDQKASS SEVKTEGLCP 
       130        140        150        160        170        180 
DSATEEEDTV ELTEFGMQNV EIPHLPQDFE VAKYNTLEKV GMEGGQEAVV VELQCSRDSR 
       190        200        210        220        230        240 
DCPFLISSHF LLDDGMETRR QFAIKKTSED ASEYFENYIE ELKKQGFLLR EHFTPEATQL 
       250        260        270        280        290        300 
ASEQLQALLL EEVMNSSTLS QEVSDLVEMI WAEALGHLEH MLLKPVNRIS LNDVSKAEGI 
       310        320        330        340        350        360 
LLLVKAALKN GETAEQLQKM MTEFYRLIPH KGTMPKEVNL GLLAKKADLC QLIRDMVNVC 
       370        380        390        400        410        420 
ETNLSKPNPP SLAKYRALRC KIEHVEQNTE EFLRVRKEVL QNHHSKSPVD VLQIFRVGRV 
       430        440        450        460        470        480 
NETTEFLSKL GNVRPLLHGS PVQNIVGILC RGLLLPKVVE DRGVQRTDVG NLGSGIYFSD 
       490        500        510        520        530        540 
SLSTSIKYSH PGETDGTRLL LICDVALGKC MDLHEKDFSL TEAPPGYDSV HGVSQTASVT 
       550        560        570        580        590        600 
TDFEDDEFVV YKTNQVKMKY IIKFSMPGDQ IKDFHPSDHT ELEEYRPEFS NFSKVEDYQL 
       610        620        630        640        650        660 
PDAKTSSSTK AGLQDASGNL VPLEDVHIKG RIIDTVAQVI VFQTYTNKSH VPIEAKYIFP 
       670        680        690        700        710        720 
LDDKAAVCGF EAFINGKHIV GEIKEKEEAQ QEYLEAVTQG HGAYLMSQDA PDVFTVSVGN 
       730        740        750        760        770        780 
LPPKAKVLIK ITYITELSIL GTVGVFFMPA TVAPWQQDKA LNENLQDTVE KICIKEIGTK 
       790        800        810        820        830        840 
QSFSLTMSIE MPYVIEFIFS DTHELKQKRT DCKAVISTME GSSLDSSGFS LHIGLSAAYL 
       850        860        870        880        890        900 
PRMWVEKHPE KESEACMLVF QPDLDVDLPD LASESEVIIC LDCSSSMEGV TFLQAKQIAL 
       910        920        930        940        950        960 
HALSLVGEKQ KVNIIQFGTG YKELFSYPKH ITSNTMAAEF IMSATPTMGN TDFWKTLRYL 
       970        980        990       1000       1010       1020 
SLLYPARGSR NILLVSDGHL QDESLTLQLV KRSRPHTRLF ACGIGSTANR HVLRILSQCG 
      1030       1040       1050       1060       1070       1080 
AGVFEYFNAK SKHSWRKQIE DQMTRLCSPS CHSVSVKWQQ LNPDVPEALQ APAQVPSLFL 
      1090       1100       1110       1120       1130       1140 
NDRLLVYGFI PHCTQATLCA LIQEKEFRTM VSTTELQKTT GTMIHKLAAR ALIRDYEDGI 
      1150       1160       1170       1180       1190       1200 
LHENETSHEM KKQTLKSLII KLSKENSLIT QFTSFVAVEK RDENESPFPD IPKVSELIAK 
      1210       1220       1230       1240       1250       1260 
EDVDFLPYMS WQGEPQEAVR NQSLLASSEW PELRLSKRKH RKIPFSKRKM ELSQPEVSED 
      1270       1280       1290       1300       1310       1320 
FEEDGLGVLP AFTSNLERGG VEKLLDLSWT ESCKPTATEP LFKKVSPWET STSSFFPILA 
      1330       1340       1350       1360       1370       1380 
PAVGSYLPPT ARAHSPASLS FASYRQVASF GSAAPPRQFD ASQFSQGPVP GTCADWIPQS 
      1390       1400       1410       1420       1430       1440 
ASCPTGPPQN PPSSPYCGIV FSGSSLSSAQ SAPLQHPGGF TTRPSAGTFP ELDSPQLHFS 
      1450       1460       1470       1480       1490       1500 
LPTDPDPIRG FGSYHPSASS PFHFQPSAAS LTANLRLPMA SALPEALCSQ SRTTPVDLCL 
      1510       1520       1530       1540       1550       1560 
LEESVGSLEG SRCPVFAFQS SDTESDELSE VLQDSCFLQI KCDTKDDSIL CFLEVKEEDE 
      1570       1580       1590       1600       1610       1620 
IVCIQHWQDA VPWTELLSLQ TEDGFWKLTP ELGLILNLNT NGLHSFLKQK GIQSLGVKGR 
      1630       1640       1650       1660       1670       1680 
ECLLDLIATM LVLQFIRTRL EKEGIVFKSL MKMDDASISR NIPWAFEAIK QASEWVRRTE 
      1690       1700       1710       1720    
GQYPSICPRL ELGNDWDSAT KQLLGLQPIS TVSPLHRVLH YSQG

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UKK3-1-unknown MVMGIF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HYSQG 1724 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)