Q9UKM7: Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

General Information

Protein names	- Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase - 3.2.1.113 {ECO:0000269\|PubMed:10409699, ECO:0000269\|PubMed:12090241, ECO:0000269\|PubMed:15713668} - ER alpha-1,2-mannosidase - ER mannosidase 1 - ERMan1 - Man9GlcNAc2-specific-processing alpha-mannosidase - Mannosidase alpha class 1B member 1
Gene names	MAN1B1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UKM7

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAACEGRRSG ALGSSQSDFL TPPVGGAPWA VATTVVMYPP PPPPPHRDFI SVTLSFGENY
        70         80         90        100        110        120
DNSKSWRRRS CWRKWKQLSR LQRNMILFLL AFLLFCGLLF YINLADHWKA LAFRLEEEQK
       130        140        150        160        170        180
MRPEIAGLKP ANPPVLPAPQ KADTDPENLP EISSQKTQRH IQRGPPHLQI RPPSQDLKDG
       190        200        210        220        230        240
TQEEATKRQE APVDPRPEGD PQRTVISWRG AVIEPEQGTE LPSRRAEVPT KPPLPPARTQ
       250        260        270        280        290        300
GTPVHLNYRQ KGVIDVFLHA WKGYRKFAWG HDELKPVSRS FSEWFGLGLT LIDALDTMWI
       310        320        330        340        350        360
LGLRKEFEEA RKWVSKKLHF EKDVDVNLFE STIRILGGLL SAYHLSGDSL FLRKAEDFGN
       370        380        390        400        410        420
RLMPAFRTPS KIPYSDVNIG TGVAHPPRWT SDSTVAEVTS IQLEFRELSR LTGDKKFQEA
       430        440        450        460        470        480
VEKVTQHIHG LSGKKDGLVP MFINTHSGLF THLGVFTLGA RADSYYEYLL KQWIQGGKQE
       490        500        510        520        530        540
TQLLEDYVEA IEGVRTHLLR HSEPSKLTFV GELAHGRFSA KMDHLVCFLP GTLALGVYHG
       550        560        570        580        590        600
LPASHMELAQ ELMETCYQMN RQMETGLSPE IVHFNLYPQP GRRDVEVKPA DRHNLLRPET
       610        620        630        640        650        660
VESLFYLYRV TGDRKYQDWG WEILQSFSRF TRVPSGGYSS INNVQDPQKP EPRDKMESFF
       670        680        690
LGETLKYLFL LFSDDPNLLS LDAYVFNTEA HPLPIWTPA

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UKM7-1-unknown	MAACEG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UKM7-37-unknown	MYPPPP...	37	inferred from electronic annotation	unknown	TISdb	inferred from TISdb
Q9UKM7-298-unknown	MWILGL...	298	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447256

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QEAPVD	193	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000440616
...PLPPAR	237	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444189
...IWTPA	699	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)