Q9UMR5: Lysosomal thioesterase PPT2

General Information

Protein names	- Lysosomal thioesterase PPT2 - PPT-2 - 3.1.2.- - S-thioesterase G14
Gene names	PPT2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UMR5

4 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Lysosomal thioesterase PPT2 - Isoform 3 of Lysosomal thioesterase PPT2

Sequence View

        10         20         30         40         50         60
MLGLCGQRLP AAWVLLLLPF LPLLLLAAPA PHRASYKPVI VVHGLFDSSY SFRHLLEYIN
        70         80         90        100        110        120
ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGVHLICY SQGGLVCRAL
       130        140        150        160        170        180
LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH
       190        200        210        220        230        240
DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG
       250        260        270        280        290        300
FYDANETVLE MEEQLVYLRD SFGLKTLLAR GAIVRCPMAG ISHTAWHSNR TLYETCIEPW

LS         10         20         30         40         50         60
MLGLCGQRLP AAWVLLLLPF LPLLLLAAPA PHRASYKPVI VVHGLFDSSY SFRHLLEYIN
        70         80         90        100        110        120
ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGVHLICY SQGGLVCRAL
       130        140        150        160        170        180
LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH
       190        200        210        220        230        240
DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG
       250        260        270        280        290        300
FYDANETVLE MEEQLVYLRD SFGLKTLLAR GAIVRCPMAG ISHTAWHSNR TLYETCIEPW

LS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UMR5-1-unknown	MLGLCG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86040
Q9UMR5-1-unknown	MLGLCG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97255
Q9UMR5-28-unknown	APAPHR...	28	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UMR5-28-unknown	APAPHR...	28	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114378
Q9UMR5-28-unknown	APAPHR...	28	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt114377
Q9UMR5-98-unknown	MAKAPQ...	98	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475276
Q9UMR5-98-unknown	MAKAPQ...	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196910
Q9UMR5-98-unknown	MAKAPQ...	98	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196909
Q9UMR5-124-unknown	MDDHNV...	124	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415350
Q9UMR5-124-unknown	MDDHNV...	124	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197321
Q9UMR5-124-unknown	MDDHNV...	124	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt197320

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FISLSS	136	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000475276
...FISLSS	136	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154802
...FISLSS	136	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154801
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000398847
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000395322
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412655
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409804
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402642
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000403457
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399320
...CNYWHD	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402159
...CNYWHD	180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155376
...CNYWHD	180	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155375
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404636
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387444
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409821
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000405631
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410001
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392069
...ALINGE	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408333
...ALINGE	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155642
...ALINGE	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155641
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409877
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000409058
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410212
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397767
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000396541
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412844
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393813
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416062
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397037
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435258
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393629
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000392744
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399332
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000433262
...TPWQSS	236	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435187
...EPWLS	302	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EPWLS	302	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81659

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)