TopFIND 4.0

Q9UNE0: Tumor necrosis factor receptor superfamily member EDAR

General Information

Protein names
- Tumor necrosis factor receptor superfamily member EDAR
- Anhidrotic ectodysplasin receptor 1
- Downless homolog
- EDA-A1 receptor
- Ectodermal dysplasia receptor
- Ectodysplasin-A receptor
Gene names EDAR
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UNE0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAHVGDCTQT PWLPVLVVSL MCSARAEYSN CGENEYYNQT TGLCQECPPC GPGEEPYLSC 
        70         80         90        100        110        120 
GYGTKDEDYG CVPCPAEKFS KGGYQICRRH KDCEGFFRAT VLTPGDMEND AECGPCLPGY 
       130        140        150        160        170        180 
YMLENRPRNI YGMVCYSCLL APPNTKECVG ATSGASANFP GTSGSSTLSP FQHAHKELSG 
       190        200        210        220        230        240 
QGHLATALII AMSTIFIMAI AIVLIIMFYI LKTKPSAPAC CTSHPGKSVE AQVSKDEEKK 
       250        260        270        280        290        300 
EAPDNVVMFS EKDEFEKLTA TPAKPTKSEN DASSENEQLL SRSVDSDEEP APDKQGSPEL 
       310        320        330        340        350        360 
CLLSLVHLAR EKSATSNKSA GIQSRRKKIL DVYANVCGVV EGLSPTELPF DCLEKTSRML 
       370        380        390        400        410        420 
SSTYNSEKAV VKTWRHLAES FGLKRDEIGG MTDGMQLFDR ISTAGYSIPE LLTKLVQIER 
       430        440    
LDAVESLCAD ILEWAGVVPP ASQPHAAS

Isoforms

- Isoform 2 of Tumor necrosis factor receptor superfamily member EDAR

Sequence View

        10         20         30         40         50         60 
MAHVGDCTQT PWLPVLVVSL MCSARAEYSN CGENEYYNQT TGLCQECPPC GPGEEPYLSC 
        70         80         90        100        110        120 
GYGTKDEDYG CVPCPAEKFS KGGYQICRRH KDCEGFFRAT VLTPGDMEND AECGPCLPGY 
       130        140        150        160        170        180 
YMLENRPRNI YGMVCYSCLL APPNTKECVG ATSGASANFP GTSGSSTLSP FQHAHKELSG 
       190        200        210        220        230        240 
QGHLATALII AMSTIFIMAI AIVLIIMFYI LKTKPSAPAC CTSHPGKSVE AQVSKDEEKK 
       250        260        270        280        290        300 
EAPDNVVMFS EKDEFEKLTA TPAKPTKSEN DASSENEQLL SRSVDSDEEP APDKQGSPEL 
       310        320        330        340        350        360 
CLLSLVHLAR EKSATSNKSA GIQSRRKKIL DVYANVCGVV EGLSPTELPF DCLEKTSRML 
       370        380        390        400        410        420 
SSTYNSEKAV VKTWRHLAES FGLKRDEIGG MTDGMQLFDR ISTAGYSIPE LLTKLVQIER 
       430        440    
LDAVESLCAD ILEWAGVVPP ASQPHAAS



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UNE0-1-unknown MAHVGD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73614
    Q9UNE0-27-unknown EYSNCG... 27 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UNE0-27-unknown EYSNCG... 27 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114157

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PHAAS 448 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PHAAS 448 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69232

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)