TopFIND 4.0

Q9UNP4: Lactosylceramide alpha-2,3-sialyltransferase

General Information

Protein names
- Lactosylceramide alpha-2,3-sialyltransferase
- 2.4.99.9
- CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase
- Ganglioside GM3 synthase
- ST3Gal V
- ST3GalV
- Sialyltransferase 9
Gene names ST3GAL5
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UNP4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRTKAAGCAE RRPLQPRTEA AAAPAGRAMP SEYTYVKLRS DCSRPSLQWY TRAQSKMRRP 
        70         80         90        100        110        120 
SLLLKDILKC TLLVFGVWIL YILKLNYTTE ECDMKKMHYV DPDHVKRAQK YAQQVLQKEC 
       130        140        150        160        170        180 
RPKFAKTSMA LLFEHRYSVD LLPFVQKAPK DSEAESKYDP PFGFRKFSSK VQTLLELLPE 
       190        200        210        220        230        240 
HDLPEHLKAK TCRRCVVIGS GGILHGLELG HTLNQFDVVI RLNSAPVEGY SEHVGNKTTI 
       250        260        270        280        290        300 
RMTYPEGAPL SDLEYYSNDL FVAVLFKSVD FNWLQAMVKK ETLPFWVRLF FWKQVAEKIP 
       310        320        330        340        350        360 
LQPKHFRILN PVIIKETAFD ILQYSEPQSR FWGRDKNVPT IGVIAVVLAT HLCDEVSLAG 
       370        380        390        400        410    
FGYDLNQPRT PLHYFDSQCM AAMNFQTMHN VTTETKFLLK LVKEGVVKDL SGGIDREF

Isoforms

- Isoform 2 of Lactosylceramide alpha-2,3-sialyltransferase - Isoform 3 of Lactosylceramide alpha-2,3-sialyltransferase

Sequence View

        10         20         30         40         50         60 
MRTKAAGCAE RRPLQPRTEA AAAPAGRAMP SEYTYVKLRS DCSRPSLQWY TRAQSKMRRP 
        70         80         90        100        110        120 
SLLLKDILKC TLLVFGVWIL YILKLNYTTE ECDMKKMHYV DPDHVKRAQK YAQQVLQKEC 
       130        140        150        160        170        180 
RPKFAKTSMA LLFEHRYSVD LLPFVQKAPK DSEAESKYDP PFGFRKFSSK VQTLLELLPE 
       190        200        210        220        230        240 
HDLPEHLKAK TCRRCVVIGS GGILHGLELG HTLNQFDVVI RLNSAPVEGY SEHVGNKTTI 
       250        260        270        280        290        300 
RMTYPEGAPL SDLEYYSNDL FVAVLFKSVD FNWLQAMVKK ETLPFWVRLF FWKQVAEKIP 
       310        320        330        340        350        360 
LQPKHFRILN PVIIKETAFD ILQYSEPQSR FWGRDKNVPT IGVIAVVLAT HLCDEVSLAG 
       370        380        390        400        410    
FGYDLNQPRT PLHYFDSQCM AAMNFQTMHN VTTETKFLLK LVKEGVVKDL SGGIDREF         10         20         30         40         50         60 
MRTKAAGCAE RRPLQPRTEA AAAPAGRAMP SEYTYVKLRS DCSRPSLQWY TRAQSKMRRP 
        70         80         90        100        110        120 
SLLLKDILKC TLLVFGVWIL YILKLNYTTE ECDMKKMHYV DPDHVKRAQK YAQQVLQKEC 
       130        140        150        160        170        180 
RPKFAKTSMA LLFEHRYSVD LLPFVQKAPK DSEAESKYDP PFGFRKFSSK VQTLLELLPE 
       190        200        210        220        230        240 
HDLPEHLKAK TCRRCVVIGS GGILHGLELG HTLNQFDVVI RLNSAPVEGY SEHVGNKTTI 
       250        260        270        280        290        300 
RMTYPEGAPL SDLEYYSNDL FVAVLFKSVD FNWLQAMVKK ETLPFWVRLF FWKQVAEKIP 
       310        320        330        340        350        360 
LQPKHFRILN PVIIKETAFD ILQYSEPQSR FWGRDKNVPT IGVIAVVLAT HLCDEVSLAG 
       370        380        390        400        410    
FGYDLNQPRT PLHYFDSQCM AAMNFQTMHN VTTETKFLLK LVKEGVVKDL SGGIDREF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UNP4-1-unknown MRTKAA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UNP4-29-unknown MPSEYT... 29 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89725
    Q9UNP4-29-unknown MPSEYT... 29 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt103014

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)