TopFIND 4.0

Q9UNU6: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

General Information

Protein names
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- 1.14.18.8 {ECO:0000250|UniProtKB:O02766}
- 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase
- CYPVIIIB1
- Cytochrome P450 8B1
- Sterol 12-alpha-hydroxylase
Gene names CYP8B1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9UNU6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLWGPVLGA LLVVIAGYLC LPGMLRQRRP WEPPLDKGTV PWLGHAMAFR KNMFEFLKRM 
        70         80         90        100        110        120 
RTKHGDVFTV QLGGQYFTFV MDPLSFGSIL KDTQRKLDFG QYAKKLVLKV FGYRSVQGDH 
       130        140        150        160        170        180 
EMIHSASTKH LRGDGLKDLN ETMLDSLSFV MLTSKGWSLD ASCWHEDSLF RFCYYILFTA 
       190        200        210        220        230        240 
GYLSLFGYTK DKEQDLLQAG ELFMEFRKFD LLFPRFVYSL LWPREWLEVG RLQRLFHKML 
       250        260        270        280        290        300 
SVSHSQEKEG ISNWLGNMLQ FLREQGVPSA MQDKFNFMML WASQGNTGPT SFWALLYLLK 
       310        320        330        340        350        360 
HPEAIRAVRE EATQVLGEAR LETKQSFAFK LGALQHTPVL DSVVEETLRL RAAPTLLRLV 
       370        380        390        400        410        420 
HEDYTLKMSS GQEYLFRHGD ILALFPYLSV HMDPDIHPEP TVFKYDRFLN PNGSRKVDFF 
       430        440        450        460        470        480 
KTGKKIHHYT MPWGSGVSIC PGRFFALSEV KLFILLMVTH FDLELVDPDT PLPHVDPQRW 
       490        500    
GFGTMQPSHD VRFRYRLHPT E

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UNU6-1-unknown MVLWGP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LHPTE 501 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)