Q9UQ07: MAPK/MAK/MRK overlapping kinase

General Information

Protein names	- MAPK/MAK/MRK overlapping kinase - 2.7.11.22 {ECO:0000250\|UniProtKB:Q9WVS4} - MOK protein kinase - Renal tumor antigen 1 - RAGE-1
Gene names	MOK
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UQ07

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of MAPK/MAK/MRK overlapping kinase - Isoform 3 of MAPK/MAK/MRK overlapping kinase - Isoform 4 of MAPK/MAK/MRK overlapping kinase - Isoform 5 of MAPK/MAK/MRK overlapping kinase - Isoform 6 of MAPK/MAK/MRK overlapping kinase

Sequence View

        10         20         30         40         50         60
MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH
        70         80         90        100        110        120
PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH
       130        140        150        160        170        180
RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT
       190        200        210        220        230        240
YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP
       250        260        270        280        290        300
FKKGSGIPLL TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
       310        320        330        340        350        360
KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVVRL
       370        380        390        400        410
SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD LKPAPQQCRL PTIVRKGGR         10         20         30         40         50         60
MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH
        70         80         90        100        110        120
PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH
       130        140        150        160        170        180
RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT
       190        200        210        220        230        240
YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP
       250        260        270        280        290        300
FKKGSGIPLL TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
       310        320        330        340        350        360
KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVVRL
       370        380        390        400        410
SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD LKPAPQQCRL PTIVRKGGR         10         20         30         40         50         60
MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH
        70         80         90        100        110        120
PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH
       130        140        150        160        170        180
RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT
       190        200        210        220        230        240
YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP
       250        260        270        280        290        300
FKKGSGIPLL TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
       310        320        330        340        350        360
KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVVRL
       370        380        390        400        410
SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD LKPAPQQCRL PTIVRKGGR         10         20         30         40         50         60
MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH
        70         80         90        100        110        120
PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH
       130        140        150        160        170        180
RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT
       190        200        210        220        230        240
YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP
       250        260        270        280        290        300
FKKGSGIPLL TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
       310        320        330        340        350        360
KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVVRL
       370        380        390        400        410
SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD LKPAPQQCRL PTIVRKGGR         10         20         30         40         50         60
MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH
        70         80         90        100        110        120
PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH
       130        140        150        160        170        180
RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT
       190        200        210        220        230        240
YKMDLWSAGC VFYEIASLQP LFPGVNELDQ ISKIHDVIGT PAQKILTKFK QSRAMNFDFP
       250        260        270        280        290        300
FKKGSGIPLL TTNLSPQCLS LLHAMVAYDP DERIAAHQAL QHPYFQEQRK TEKRALGSHR
       310        320        330        340        350        360
KAGFPEHPVA PEPLSNSCQI SKEGRKQKQS LKQEEDRPKR RGPAYVMELP KLKLSGVVRL
       370        380        390        400        410
SSYSSPTLQS VLGSGTNGRV PVLRPLKCIP ASKKTDPQKD LKPAPQQCRL PTIVRKGGR

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9UQ07-1-unknown	MKNYKA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9UQ07-1-unknown	MKNYKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81380
Q9UQ07-1-unknown	MKNYKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81383
Q9UQ07-1-unknown	MKNYKA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81384
Q9UQ07-235-unknown	MNFDFP...	235	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81382
Q9UQ07-235-unknown	MNFDFP...	235	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000193029
Q9UQ07-235-unknown	MNFDFP...	235	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108658
Q9UQ07-235-unknown	MNFDFP...	235	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108657
Q9UQ07-347-unknown	MELPKL...	347	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81381
Q9UQ07-347-unknown	MELPKL...	347	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108623
Q9UQ07-347-unknown	MELPKL...	347	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt108622

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TKFKQS	231	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76998
...TKFKQS	231	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92054
...TKFKQS	231	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92053
...RKGGR	419	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...RKGGR	419	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76999
...RKGGR	419	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77001
...RKGGR	419	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77002

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)