Q9UQ13: Leucine-rich repeat protein SHOC-2

General Information

Protein names	- Leucine-rich repeat protein SHOC-2 - Protein soc-2 homolog - Protein sur-8 homolog
Gene names	SHOC2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9UQ13

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSSLGKEKD SKEKDPKVPS AKEREKEAKA SGGFGKESKE KEPKTKGKDA KDGKKDSSAA
        70         80         90        100        110        120
QPGVAFSVDN TIKRPNPAPG TRKKSSNAEV IKELNKCREE NSMRLDLSKR SIHILPSSIK
       130        140        150        160        170        180
ELTQLTELYL YSNKLQSLPA EVGCLVNLMT LALSENSLTS LPDSLDNLKK LRMLDLRHNK
       190        200        210        220        230        240
LREIPSVVYR LDSLTTLYLR FNRITTVEKD IKNLSKLSML SIRENKIKQL PAEIGELCNL
       250        260        270        280        290        300
ITLDVAHNQL EHLPKEIGNC TQITNLDLQH NELLDLPDTI GNLSSLSRLG LRYNRLSAIP
       310        320        330        340        350        360
RSLAKCSALE ELNLENNNIS TLPESLLSSL VKLNSLTLAR NCFQLYPVGG PSQFSTIYSL
       370        380        390        400        410        420
NMEHNRINKI PFGIFSRAKV LSKLNMKDNQ LTSLPLDFGT WTSMVELNLA TNQLTKIPED
       430        440        450        460        470        480
VSGLVSLEVL ILSNNLLKKL PHGLGNLRKL RELDLEENKL ESLPNEIAYL KDLQKLVLTN
       490        500        510        520        530        540
NQLTTLPRGI GHLTNLTHLG LGENLLTHLP EEIGTLENLE ELYLNDNPNL HSLPFELALC
       550        560        570        580
SKLSIMSIEN CPLSHLPPQI VAGGPSFIIQ FLKMQGPYRA MV

Isoforms

- Isoform 2 of Leucine-rich repeat protein SHOC-2

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9UQ13-1-unknown	MSSSLG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9UQ13-1-unknown	MSSSLG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt89618
Q9UQ13-2-acetylation	SSSLGK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9UQ13-2-acetylation	SSSLGK...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9UQ13-2-acetylation	SSSLGK...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162706
Q9UQ13-67-unknown	SVDNTI...	67			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UQ13-67-unknown	SVDNTI...	67			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9UQ13-67-unknown	SVDNTI...	67		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160283
Q9UQ13-67-	SVDNTI...	67			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9UQ13-67-	SVDNTI...	67			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...YRAMV	582	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...YRAMV	582	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85236

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)