Q9UQC9: Calcium-activated chloride channel regulator 2
Protein names | - Calcium-activated chloride channel regulator 2 - 3.4.-.- {ECO:0000250|UniProtKB:A8K7I4} - Calcium-activated chloride channel family member 2 - hCLCA2 - Calcium-activated chloride channel protein 3 - CaCC-3 - hCaCC-3 - Calcium-activated chloride channel regulator 2, 109 kDa form - Calcium-activated chloride channel regulator 2, 35 kDa form |
---|---|
Gene names | CLCA2 |
Organism | Homo sapiens |
Protease Family | M87.003 |
Protease ID | M87.003 |
Chromosome location | |
UniProt ID | Q9UQC9 |
4
N-termini
3
C-termini
1
Cleavages
1
Substrates
Sequence
10 20 30 40 50 60
MTQRSIAGPI CNLKFVTLLV ALSSELPFLG AGVQLQDNGY NGLLIAINPQ VPENQNLISN
70 80 90 100 110 120
IKEMITEASF YLFNATKRRV FFRNIKILIP ATWKANNNSK IKQESYEKAN VIVTDWYGAH
130 140 150 160 170 180
GDDPYTLQYR GCGKEGKYIH FTPNFLLNDN LTAGYGSRGR VFVHEWAHLR WGVFDEYNND
190 200 210 220 230 240
KPFYINGQNQ IKVTRCSSDI TGIFVCEKGP CPQENCIISK LFKEGCTFIY NSTQNATASI
250 260 270 280 290 300
MFMQSLSSVV EFCNASTHNQ EAPNLQNQMC SLRSAWDVIT DSADFHHSFP MNGTELPPPP
310 320 330 340 350 360
TFSLVQAGDK VVCLVLDVSS KMAEADRLLQ LQQAAEFYLM QIVEIHTFVG IASFDSKGEI
370 380 390 400 410 420
RAQLHQINSN DDRKLLVSYL PTTVSAKTDI SICSGLKKGF EVVEKLNGKA YGSVMILVTS
430 440 450 460 470 480
GDDKLLGNCL PTVLSSGSTI HSIALGSSAA PNLEELSRLT GGLKFFVPDI SNSNSMIDAF
490 500 510 520 530 540
SRISSGTGDI FQQHIQLEST GENVKPHHQL KNTVTVDNTV GNDTMFLVTW QASGPPEIIL
550 560 570 580 590 600
FDPDGRKYYT NNFITNLTFR TASLWIPGTA KPGHWTYTLN NTHHSLQALK VTVTSRASNS
610 620 630 640 650 660
AVPPATVEAF VERDSLHFPH PVMIYANVKQ GFYPILNATV TATVEPETGD PVTLRLLDDG
670 680 690 700 710 720
AGADVIKNDG IYSRYFFSFA ANGRYSLKVH VNHSPSISTP AHSIPGSHAM YVPGYTANGN
730 740 750 760 770 780
IQMNAPRKSV GRNEEERKWG FSRVSSGGSF SVLGVPAGPH PDVFPPCKII DLEAVKVEEE
790 800 810 820 830 840
LTLSWTAPGE DFDQGQATSY EIRMSKSLQN IQDDFNNAIL VNTSKRNPQQ AGIREIFTFS
850 860 870 880 890 900
PQISTNGPEH QPNGETHESH RIYVAIRAMD RNSLQSAVSN IAQAPLFIPP NSDPVPARDY
910 920 930 940
LILKGVLTAM GLIGIICLII VVTHHTLSRK KRADKKENGT KLL
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
4 N-termini - 3 C-termini - 1 Cleavages - 1 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9UQC9-0-unknown | LMTQRS... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UQC9-32-unknown | GVQLQD... | 32 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UQC9-33-unknown | VQLQDN... | 33 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9UQC9-709-unknown | AMYVPG... | 709 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC8364 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...IPGSHA | 708 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC8364 | |||
...GTKLL | 943 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CLCA2_HUMAN | 708 | GSHA.|.AMYV | inferred from experiment | unknown | MEROPS | Brett TJ | Yurtsever Z et al.:Self-cleavage of human CLCA1 pr... (M87.001) | 23112050, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CLCA2_HUMAN | 708 | GSHA.|.AMYV | inferred from experiment | unknown | MEROPS | Brett TJ | Yurtsever Z et al.:Self-cleavage of human CLCA1 pr... (M87.001) | 23112050, |