Q9WTQ5: A-kinase anchor protein 12
| Protein names | - A-kinase anchor protein 12 - AKAP-12 - Germ cell lineage protein gercelin - Src-suppressed C kinase substrate - SSeCKS |
|---|---|
| Gene names | Akap12 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9WTQ5 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MGAGSSTEQR SPEQPAESDT PSELELSGHG PAAEASGAAG DPADADPATK LPQKNGQLSA
70 80 90 100 110 120
VNGVAEQEDV HVQEESQDGQ EEEVTVEDVG QRESEDVKEK DRAKEMAASS TVVEDITKDE
130 140 150 160 170 180
QEETPEIIEQ IPASESNVEE MAQAAESQAN DVGFKKVFKF VGFKFTVKKD KNEKSDTVQL
190 200 210 220 230 240
LTVKKDEGEG AEASVGAGDH QEPGVETVGE SASKESELKQ STEKQEGTLK QAQSSTEIPL
250 260 270 280 290 300
QAESGQGTEE EAAKDGEENR EKEPTKPLES PTSPVSNETT SSFKKFFTHG WAGWRKKTSF
310 320 330 340 350 360
KKPKEDDLET SEKRKEQEAE KVDEEEGEKT EPAPAEEQEP AEGTDQARLS ADYEKVELPL
370 380 390 400 410 420
EDQVGDLEAL SEKCAPLATE VFDEKTEAHQ EVVAEVHVST VEKMTKGQGG AEVEGDVVVE
430 440 450 460 470 480
GSGESLPPEK LAETQEVPQE AEPVEELMKT KEVCVSGGDH TQLTDLSPEE KMLPKHPEGI
490 500 510 520 530 540
VSEVEMLSSQ ERIKVQGSPL KKLFSSSGLK KLSGKKQKGK RGGGGGDEEP GEYQHIQTES
550 560 570 580 590 600
PESADEQKGE SSASSPEEPE EIACLEKGPS EAPQEAEAEE GATSDGEKKR EGITPWASFK
610 620 630 640 650 660
KMVTPKKRVR RPSESDKEEE LDKVKSATLS STESTASGMQ DEVRAVGEEQ RSEEPKRRVD
670 680 690 700 710 720
TSVSWEALIC VGSSKKRARK ASSSDDEGGP RTLGGDGHRA EEASKDKEAD ALPASTQEQD
730 740 750 760 770 780
QAHGSSSPEP AGSPSEGEGV STWESFKRLV TPRKKSKSKL EERAEDSGAE QLASEIEPSR
790 800 810 820 830 840
EESWVSIKKF IPGRRKKRAD GKQEQAAVED SGPGEINEDD PDVPAVVPLS EYDAVEREKL
850 860 870 880 890 900
EAQRAQENVE LPQLKGAVYV SEELSKTLVH TVSVAVIDGT RAVTSAEERS PSWISASMTE
910 920 930 940 950 960
PLEHAEGVAT PPVGEVTEKD ITAEATPALA QTLPGGKDAH DDIVTSEVDF TSEAVTAAET
970 980 990 1000 1010 1020
TEALRAEELT EASGAEETTD MVSAVSQLSD SPDTTEEATP VQEVEGGMLD TEEQERQTQA
1030 1040 1050 1060 1070 1080
VLQAVADKVK EDSQVPATQT LQRAGPKALE KVEEVEEDSE VLATEKEKDV VPEGPVQEAE
1090 1100 1110 1120 1130 1140
TEHLAQGSET VQATPESLEV PEVTEDVDRA TTCQVIKHQQ LMEQAVAPES SETLTDSETN
1150 1160 1170 1180 1190 1200
GSTPLADSDT PNGTQQDETV DSQDSNAIAA VKQSQVTEEE AAAAQTEGPS TPSSFPAQEE
1210 1220 1230 1240 1250 1260
HREKPGRDVL EPTQALAAGA VPILAKAEVG QEGEAGQFDG EKVKDGQCVK ELEVPVHTGP
1270 1280 1290 1300 1310 1320
NSQKTADLTR DSEVMEVARC QETESNEEQS ISPEKREMGT DVEKEETETK TEQASEEHEQ
1330 1340 1350 1360 1370 1380
ETAAPEHEGT HPKPVLTADM PHSERGKALG SLEGSPSLPD QDKADCIEVQ VQSSDTPVTQ
1390 1400 1410 1420 1430 1440
TTEAVKKVEE TVATSEMDES LECAGAQSLP AEKLSETGGY GTLQHGEDTV PQGPESQAES
1450 1460 1470 1480 1490 1500
IPIIVTPAPE SILHSDLQRE VSASQKQRSD EDNKPDAGPD AAGKESAARE KILRAEPEIL
1510 1520 1530 1540 1550 1560
ELESKSNKIV QSVIQTAVDQ FARTETAPET HASDLQNQVP VMQADSQGAQ QMLDKDESDL
1570 1580 1590 1600 1610 1620
QVSPQDGTLS AVAQEGLAVS DSSEGMSKAS EMITTLAVES ASVKESVEKL PLQCKDEKEH
1630 1640 1650 1660 1670 1680
AADGPQHQSL AKAEADASGN LTKESPDTNG PKLTEEGDAL KEEMNKAQTE EDDLQEPKGD
LTES
Isoforms
- Isoform 2 of A-kinase anchor protein 12 - Isoform 2 of A-kinase anchor protein 12Sequence View
10 20 30 40 50 60
MGAGSSTEQR SPEQPAESDT PSELELSGHG PAAEASGAAG DPADADPATK LPQKNGQLSA
70 80 90 100 110 120
VNGVAEQEDV HVQEESQDGQ EEEVTVEDVG QRESEDVKEK DRAKEMAASS TVVEDITKDE
130 140 150 160 170 180
QEETPEIIEQ IPASESNVEE MAQAAESQAN DVGFKKVFKF VGFKFTVKKD KNEKSDTVQL
190 200 210 220 230 240
LTVKKDEGEG AEASVGAGDH QEPGVETVGE SASKESELKQ STEKQEGTLK QAQSSTEIPL
250 260 270 280 290 300
QAESGQGTEE EAAKDGEENR EKEPTKPLES PTSPVSNETT SSFKKFFTHG WAGWRKKTSF
310 320 330 340 350 360
KKPKEDDLET SEKRKEQEAE KVDEEEGEKT EPAPAEEQEP AEGTDQARLS ADYEKVELPL
370 380 390 400 410 420
EDQVGDLEAL SEKCAPLATE VFDEKTEAHQ EVVAEVHVST VEKMTKGQGG AEVEGDVVVE
430 440 450 460 470 480
GSGESLPPEK LAETQEVPQE AEPVEELMKT KEVCVSGGDH TQLTDLSPEE KMLPKHPEGI
490 500 510 520 530 540
VSEVEMLSSQ ERIKVQGSPL KKLFSSSGLK KLSGKKQKGK RGGGGGDEEP GEYQHIQTES
550 560 570 580 590 600
PESADEQKGE SSASSPEEPE EIACLEKGPS EAPQEAEAEE GATSDGEKKR EGITPWASFK
610 620 630 640 650 660
KMVTPKKRVR RPSESDKEEE LDKVKSATLS STESTASGMQ DEVRAVGEEQ RSEEPKRRVD
670 680 690 700 710 720
TSVSWEALIC VGSSKKRARK ASSSDDEGGP RTLGGDGHRA EEASKDKEAD ALPASTQEQD
730 740 750 760 770 780
QAHGSSSPEP AGSPSEGEGV STWESFKRLV TPRKKSKSKL EERAEDSGAE QLASEIEPSR
790 800 810 820 830 840
EESWVSIKKF IPGRRKKRAD GKQEQAAVED SGPGEINEDD PDVPAVVPLS EYDAVEREKL
850 860 870 880 890 900
EAQRAQENVE LPQLKGAVYV SEELSKTLVH TVSVAVIDGT RAVTSAEERS PSWISASMTE
910 920 930 940 950 960
PLEHAEGVAT PPVGEVTEKD ITAEATPALA QTLPGGKDAH DDIVTSEVDF TSEAVTAAET
970 980 990 1000 1010 1020
TEALRAEELT EASGAEETTD MVSAVSQLSD SPDTTEEATP VQEVEGGMLD TEEQERQTQA
1030 1040 1050 1060 1070 1080
VLQAVADKVK EDSQVPATQT LQRAGPKALE KVEEVEEDSE VLATEKEKDV VPEGPVQEAE
1090 1100 1110 1120 1130 1140
TEHLAQGSET VQATPESLEV PEVTEDVDRA TTCQVIKHQQ LMEQAVAPES SETLTDSETN
1150 1160 1170 1180 1190 1200
GSTPLADSDT PNGTQQDETV DSQDSNAIAA VKQSQVTEEE AAAAQTEGPS TPSSFPAQEE
1210 1220 1230 1240 1250 1260
HREKPGRDVL EPTQALAAGA VPILAKAEVG QEGEAGQFDG EKVKDGQCVK ELEVPVHTGP
1270 1280 1290 1300 1310 1320
NSQKTADLTR DSEVMEVARC QETESNEEQS ISPEKREMGT DVEKEETETK TEQASEEHEQ
1330 1340 1350 1360 1370 1380
ETAAPEHEGT HPKPVLTADM PHSERGKALG SLEGSPSLPD QDKADCIEVQ VQSSDTPVTQ
1390 1400 1410 1420 1430 1440
TTEAVKKVEE TVATSEMDES LECAGAQSLP AEKLSETGGY GTLQHGEDTV PQGPESQAES
1450 1460 1470 1480 1490 1500
IPIIVTPAPE SILHSDLQRE VSASQKQRSD EDNKPDAGPD AAGKESAARE KILRAEPEIL
1510 1520 1530 1540 1550 1560
ELESKSNKIV QSVIQTAVDQ FARTETAPET HASDLQNQVP VMQADSQGAQ QMLDKDESDL
1570 1580 1590 1600 1610 1620
QVSPQDGTLS AVAQEGLAVS DSSEGMSKAS EMITTLAVES ASVKESVEKL PLQCKDEKEH
1630 1640 1650 1660 1670 1680
AADGPQHQSL AKAEADASGN LTKESPDTNG PKLTEEGDAL KEEMNKAQTE EDDLQEPKGD
LTES
10 20 30 40 50 60
MGAGSSTEQR SPEQPAESDT PSELELSGHG PAAEASGAAG DPADADPATK LPQKNGQLSA
70 80 90 100 110 120
VNGVAEQEDV HVQEESQDGQ EEEVTVEDVG QRESEDVKEK DRAKEMAASS TVVEDITKDE
130 140 150 160 170 180
QEETPEIIEQ IPASESNVEE MAQAAESQAN DVGFKKVFKF VGFKFTVKKD KNEKSDTVQL
190 200 210 220 230 240
LTVKKDEGEG AEASVGAGDH QEPGVETVGE SASKESELKQ STEKQEGTLK QAQSSTEIPL
250 260 270 280 290 300
QAESGQGTEE EAAKDGEENR EKEPTKPLES PTSPVSNETT SSFKKFFTHG WAGWRKKTSF
310 320 330 340 350 360
KKPKEDDLET SEKRKEQEAE KVDEEEGEKT EPAPAEEQEP AEGTDQARLS ADYEKVELPL
370 380 390 400 410 420
EDQVGDLEAL SEKCAPLATE VFDEKTEAHQ EVVAEVHVST VEKMTKGQGG AEVEGDVVVE
430 440 450 460 470 480
GSGESLPPEK LAETQEVPQE AEPVEELMKT KEVCVSGGDH TQLTDLSPEE KMLPKHPEGI
490 500 510 520 530 540
VSEVEMLSSQ ERIKVQGSPL KKLFSSSGLK KLSGKKQKGK RGGGGGDEEP GEYQHIQTES
550 560 570 580 590 600
PESADEQKGE SSASSPEEPE EIACLEKGPS EAPQEAEAEE GATSDGEKKR EGITPWASFK
610 620 630 640 650 660
KMVTPKKRVR RPSESDKEEE LDKVKSATLS STESTASGMQ DEVRAVGEEQ RSEEPKRRVD
670 680 690 700 710 720
TSVSWEALIC VGSSKKRARK ASSSDDEGGP RTLGGDGHRA EEASKDKEAD ALPASTQEQD
730 740 750 760 770 780
QAHGSSSPEP AGSPSEGEGV STWESFKRLV TPRKKSKSKL EERAEDSGAE QLASEIEPSR
790 800 810 820 830 840
EESWVSIKKF IPGRRKKRAD GKQEQAAVED SGPGEINEDD PDVPAVVPLS EYDAVEREKL
850 860 870 880 890 900
EAQRAQENVE LPQLKGAVYV SEELSKTLVH TVSVAVIDGT RAVTSAEERS PSWISASMTE
910 920 930 940 950 960
PLEHAEGVAT PPVGEVTEKD ITAEATPALA QTLPGGKDAH DDIVTSEVDF TSEAVTAAET
970 980 990 1000 1010 1020
TEALRAEELT EASGAEETTD MVSAVSQLSD SPDTTEEATP VQEVEGGMLD TEEQERQTQA
1030 1040 1050 1060 1070 1080
VLQAVADKVK EDSQVPATQT LQRAGPKALE KVEEVEEDSE VLATEKEKDV VPEGPVQEAE
1090 1100 1110 1120 1130 1140
TEHLAQGSET VQATPESLEV PEVTEDVDRA TTCQVIKHQQ LMEQAVAPES SETLTDSETN
1150 1160 1170 1180 1190 1200
GSTPLADSDT PNGTQQDETV DSQDSNAIAA VKQSQVTEEE AAAAQTEGPS TPSSFPAQEE
1210 1220 1230 1240 1250 1260
HREKPGRDVL EPTQALAAGA VPILAKAEVG QEGEAGQFDG EKVKDGQCVK ELEVPVHTGP
1270 1280 1290 1300 1310 1320
NSQKTADLTR DSEVMEVARC QETESNEEQS ISPEKREMGT DVEKEETETK TEQASEEHEQ
1330 1340 1350 1360 1370 1380
ETAAPEHEGT HPKPVLTADM PHSERGKALG SLEGSPSLPD QDKADCIEVQ VQSSDTPVTQ
1390 1400 1410 1420 1430 1440
TTEAVKKVEE TVATSEMDES LECAGAQSLP AEKLSETGGY GTLQHGEDTV PQGPESQAES
1450 1460 1470 1480 1490 1500
IPIIVTPAPE SILHSDLQRE VSASQKQRSD EDNKPDAGPD AAGKESAARE KILRAEPEIL
1510 1520 1530 1540 1550 1560
ELESKSNKIV QSVIQTAVDQ FARTETAPET HASDLQNQVP VMQADSQGAQ QMLDKDESDL
1570 1580 1590 1600 1610 1620
QVSPQDGTLS AVAQEGLAVS DSSEGMSKAS EMITTLAVES ASVKESVEKL PLQCKDEKEH
1630 1640 1650 1660 1670 1680
AADGPQHQSL AKAEADASGN LTKESPDTNG PKLTEEGDAL KEEMNKAQTE EDDLQEPKGD
LTES
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9WTQ5-2-unknown | GAGSST... | 2 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9WTQ5-2-unknown | GAGSST... | 2 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...DLTES | 1684 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...DLTES | 1684 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt62229 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|