TopFIND 4.0

Q9WU03: Kunitz-type protease inhibitor 2

General Information

Protein names
- Kunitz-type protease inhibitor 2
- Hepatocyte growth factor activator inhibitor type 2
- HAI-2
Gene names Spint2
Organism Mus musculus
Protease Family
Protease ID I02.009
Chromosome location
UniProt ID Q9WU03

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAQLCELRRG RALLALVASL LLSGAQVASR ELDVHESCGV SKVVGKCRAS IPRWWYNITD 
        70         80         90        100        110        120 
GSCQPFVYGG CEGNGNNYQS KEECLDKCAG VTENTTDDMA RNRNGADSSV LSVPRKQSAE 
       130        140        150        160        170        180 
DLSAEIFNYE EYCVPKAVTG PCRAAFPRWY YDTEKNSCIS FIYGGCRGNK NSYLSQEACM 
       190        200        210        220        230        240 
QHCSGKQMHP FLTPGLKAVI LVGLFLMVLI LLLGTSMVCL IRVVRRKQER ALRTVWSTAD 
       250    
DKEQLVKNTC VL

Isoforms

- Isoform 2 of Kunitz-type protease inhibitor 2 - Isoform 3 of Kunitz-type protease inhibitor 2

Sequence View

        10         20         30         40         50         60 
MAQLCELRRG RALLALVASL LLSGAQVASR ELDVHESCGV SKVVGKCRAS IPRWWYNITD 
        70         80         90        100        110        120 
GSCQPFVYGG CEGNGNNYQS KEECLDKCAG VTENTTDDMA RNRNGADSSV LSVPRKQSAE 
       130        140        150        160        170        180 
DLSAEIFNYE EYCVPKAVTG PCRAAFPRWY YDTEKNSCIS FIYGGCRGNK NSYLSQEACM 
       190        200        210        220        230        240 
QHCSGKQMHP FLTPGLKAVI LVGLFLMVLI LLLGTSMVCL IRVVRRKQER ALRTVWSTAD 
       250    
DKEQLVKNTC VL         10         20         30         40         50         60 
MAQLCELRRG RALLALVASL LLSGAQVASR ELDVHESCGV SKVVGKCRAS IPRWWYNITD 
        70         80         90        100        110        120 
GSCQPFVYGG CEGNGNNYQS KEECLDKCAG VTENTTDDMA RNRNGADSSV LSVPRKQSAE 
       130        140        150        160        170        180 
DLSAEIFNYE EYCVPKAVTG PCRAAFPRWY YDTEKNSCIS FIYGGCRGNK NSYLSQEACM 
       190        200        210        220        230        240 
QHCSGKQMHP FLTPGLKAVI LVGLFLMVLI LLLGTSMVCL IRVVRRKQER ALRTVWSTAD 
       250    
DKEQLVKNTC VL



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Physiological Relevance:


Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9WU03-1-unknown MAQLCE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90474
    Q9WU03-1-unknown MAQLCE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90475
    Q9WU03-28-unknown ASRELD... 28 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NTCVL 252 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NTCVL 252 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt86092

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)