TopFIND 4.0

Q9WUW3: Complement factor I

General Information

Protein names
- Complement factor I
- 3.4.21.45
- C3B/C4B inactivator
- Complement factor I heavy chain
- Complement factor I light chain
Gene names Cfi
Organism Rattus norvegicus
Protease Family
Protease ID S01.199
Chromosome location
UniProt ID Q9WUW3

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLALLILLL LNPHLSSSKN TPASGQPQED LVEQKCLLKN YTHHSCDKVF CQPWQKCIEG 
        70         80         90        100        110        120 
TCACKLPYQC PKAGTPVCAT NGRGYPTYCH LKSFECLHPE IKFSNNGTCT AEEKFNVSLI 
       130        140        150        160        170        180 
YGSTDTEGIV QVKLVDQDEK MFICKNSWST VEANVACFDL GFPLGVRDIQ GRFNIPVNHK 
       190        200        210        220        230        240 
INSTECLHVR CQGVETSLAE CTFTKKSSKA PHGLAGVVCY TQDADFPTSQ SFQCVNGKRI 
       250        260        270        280        290        300 
PQEKACDGVN DCGDQSDELC CKGCRGQAFL CKSGVCIPNQ RKCNGEVDCI TGEDESGCEE 
       310        320        330        340        350        360 
DKKNKIHKGL ARSDQGGETE IETEETEMLT PDMDTERKRI KSLLPKLSCG VKRNTHIRRK 
       370        380        390        400        410        420 
RVVGGKPAEM GDYPWQVAIK DGDRITCGGI YIGGCWILTA AHCVRPSRYR NYQVWTSLLD 
       430        440        450        460        470        480 
WLKPNSQLAV QGVSRVVVHE KYNGATYQND IALVEMKKHP GKKECELINS VPACVPWSPY 
       490        500        510        520        530        540 
LFQPNDRCII SGWGREKDNQ KVYSLRWGEV DLIGNCSRFY PGRYYEKEMQ CAGTSDGSID 
       550        560        570        580        590        600 
ACKGDSGGPL VCKDVNNVTY VWGIVSWGEN CGKPEFPGVY TRVASYFDWI SYYVGRPLVS 
   
QYNV

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9WUW3-19-unknown KNTPAS... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9WUW3-362-unknown VVGGKP... 362 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RNTHIR 357 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SQYNV 604 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)