TopFIND 4.0

Q9WVS6: E3 ubiquitin-protein ligase parkin {ECO:0000305}

General Information

Protein names
- E3 ubiquitin-protein ligase parkin {ECO:0000305}
- 2.3.2.31 {ECO:0000250|UniProtKB:O60260}
- Parkin RBR E3 ubiquitin-protein ligase {ECO:0000250|UniProtKB:O60260}
Gene names Park2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9WVS6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQNCD 
        70         80         90        100        110        120 
LEQQSIVHIV QRPRRRSHET NASGGDEPQS TSEGSIWESR SLTRVDLSSH TLPVDSVGLA 
       130        140        150        160        170        180 
VILDTDSKRD SEAARGPVKP TYNSFFIYCK GPCHKVQPGK LRVQCGTCKQ ATLTLAQGPS 
       190        200        210        220        230        240 
CWDDVLIPNR MSGECQSPDC PGTRAEFFFK CGAHPTSDKD TSVALNLITS NRRSIPCIAC 
       250        260        270        280        290        300 
TDVRSPVLVF QCNHRHVICL DCFHLYCVTR LNDRQFVHDA QLGYSLPCVA GCPNSLIKEL 
       310        320        330        340        350        360 
HHFRILGEEQ YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG 
       370        380        390        400        410        420 
FVFCRDCKEA YHEGDCDSLL EPSGATSQAY RVDKRAAEQA RWEEASKETI KKTTKPCPRC 
       430        440        450        460    
NVPIEKNGGC MHMKCPQPQC KLEWCWNCGC EWNRACMGDH WFDV

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase parkin - Isoform 3 of E3 ubiquitin-protein ligase parkin

Sequence View

        10         20         30         40         50         60 
MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQNCD 
        70         80         90        100        110        120 
LEQQSIVHIV QRPRRRSHET NASGGDEPQS TSEGSIWESR SLTRVDLSSH TLPVDSVGLA 
       130        140        150        160        170        180 
VILDTDSKRD SEAARGPVKP TYNSFFIYCK GPCHKVQPGK LRVQCGTCKQ ATLTLAQGPS 
       190        200        210        220        230        240 
CWDDVLIPNR MSGECQSPDC PGTRAEFFFK CGAHPTSDKD TSVALNLITS NRRSIPCIAC 
       250        260        270        280        290        300 
TDVRSPVLVF QCNHRHVICL DCFHLYCVTR LNDRQFVHDA QLGYSLPCVA GCPNSLIKEL 
       310        320        330        340        350        360 
HHFRILGEEQ YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG 
       370        380        390        400        410        420 
FVFCRDCKEA YHEGDCDSLL EPSGATSQAY RVDKRAAEQA RWEEASKETI KKTTKPCPRC 
       430        440        450        460    
NVPIEKNGGC MHMKCPQPQC KLEWCWNCGC EWNRACMGDH WFDV         10         20         30         40         50         60 
MIVFVRFNSS YGFPVEVDSD TSILQLKEVV AKRQGVPADQ LRVIFAGKEL PNHLTVQNCD 
        70         80         90        100        110        120 
LEQQSIVHIV QRPRRRSHET NASGGDEPQS TSEGSIWESR SLTRVDLSSH TLPVDSVGLA 
       130        140        150        160        170        180 
VILDTDSKRD SEAARGPVKP TYNSFFIYCK GPCHKVQPGK LRVQCGTCKQ ATLTLAQGPS 
       190        200        210        220        230        240 
CWDDVLIPNR MSGECQSPDC PGTRAEFFFK CGAHPTSDKD TSVALNLITS NRRSIPCIAC 
       250        260        270        280        290        300 
TDVRSPVLVF QCNHRHVICL DCFHLYCVTR LNDRQFVHDA QLGYSLPCVA GCPNSLIKEL 
       310        320        330        340        350        360 
HHFRILGEEQ YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG 
       370        380        390        400        410        420 
FVFCRDCKEA YHEGDCDSLL EPSGATSQAY RVDKRAAEQA RWEEASKETI KKTTKPCPRC 
       430        440        450        460    
NVPIEKNGGC MHMKCPQPQC KLEWCWNCGC EWNRACMGDH WFDV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9WVS6-1-unknown MIVFVR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9WVS6-1-unknown MIVFVR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86213
    Q9WVS6-1-unknown MIVFVR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt86214

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HWFDV 464 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)