TopFIND 4.0

Q9Y217: Myotubularin-related protein 6

General Information

Protein names
- Myotubularin-related protein 6
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase {ECO:0000305}
- 3.1.3.95 {ECO:0000269|PubMed:22647598}
- Phosphatidylinositol-3-phosphate phosphatase {ECO:0000305}
- 3.1.3.64 {ECO:0000269|PubMed:19038970, ECO:0000269|PubMed:22647598, ECO:0000305|PubMed:24591580}
Gene names MTMR6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y217

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEHIRTTKVE QVKLLDRFST SNKSLTGTLY LTATHLLFID SHQKETWILH HHIASVEKLA 
        70         80         90        100        110        120 
LTTSGCPLVI QCKNFRTVHF IVPRERDCHD IYNSLLQLSK QAKYEDLYAF SYNPKQNDSE 
       130        140        150        160        170        180 
RLQGWQLIDL AEEYKRMGVP NSHWQLSDAN RDYKICETYP RELYVPRIAS KPIIVGSSKF 
       190        200        210        220        230        240 
RSKGRFPVLS YYHQDKEAAI CRCSQPLSGF SARCLEDEHL LQAISKANPV NRYMYVMDTR 
       250        260        270        280        290        300 
PKLNAMANRA AGKGYENEDN YSNIRFQFVG IENIHVMRSS LQKLLEVNGT KGLSVNDFYS 
       310        320        330        340        350        360 
GLESSGWLRH IKAVMDAAIF LAKAITVENA SVLVHCSDGW DRTSQVCSLG SLLLDSYYRT 
       370        380        390        400        410        420 
IKGFMVLIEK DWISFGHKFS ERCGQLDGDP KEVSPVFTQF LECVWHLTEQ FPQAFEFSEA 
       430        440        450        460        470        480 
FLLQIHEHIH SCQFGNFLGN CQKEREELKL KEKTYSLWPF LLEDQKKYLN PLYSSESHRF 
       490        500        510        520        530        540 
TVLEPNTVSF NFKFWRNMYH QFDRTLHPRQ SVFNIIMNMN EQNKQLEKDI KDLESKIKQR 
       550        560        570        580        590        600 
KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND ALRTIEGSSP ADNRYSEYAE 
       610        620    
EFSKSEPAVV SLEYGVARMT C

Isoforms

- Isoform 2 of Myotubularin-related protein 6

Sequence View

        10         20         30         40         50         60 
MEHIRTTKVE QVKLLDRFST SNKSLTGTLY LTATHLLFID SHQKETWILH HHIASVEKLA 
        70         80         90        100        110        120 
LTTSGCPLVI QCKNFRTVHF IVPRERDCHD IYNSLLQLSK QAKYEDLYAF SYNPKQNDSE 
       130        140        150        160        170        180 
RLQGWQLIDL AEEYKRMGVP NSHWQLSDAN RDYKICETYP RELYVPRIAS KPIIVGSSKF 
       190        200        210        220        230        240 
RSKGRFPVLS YYHQDKEAAI CRCSQPLSGF SARCLEDEHL LQAISKANPV NRYMYVMDTR 
       250        260        270        280        290        300 
PKLNAMANRA AGKGYENEDN YSNIRFQFVG IENIHVMRSS LQKLLEVNGT KGLSVNDFYS 
       310        320        330        340        350        360 
GLESSGWLRH IKAVMDAAIF LAKAITVENA SVLVHCSDGW DRTSQVCSLG SLLLDSYYRT 
       370        380        390        400        410        420 
IKGFMVLIEK DWISFGHKFS ERCGQLDGDP KEVSPVFTQF LECVWHLTEQ FPQAFEFSEA 
       430        440        450        460        470        480 
FLLQIHEHIH SCQFGNFLGN CQKEREELKL KEKTYSLWPF LLEDQKKYLN PLYSSESHRF 
       490        500        510        520        530        540 
TVLEPNTVSF NFKFWRNMYH QFDRTLHPRQ SVFNIIMNMN EQNKQLEKDI KDLESKIKQR 
       550        560        570        580        590        600 
KNKQTDGILT KELLHSVHPE SPNLKTSLCF KEQTLLPVND ALRTIEGSSP ADNRYSEYAE 
       610        620    
EFSKSEPAVV SLEYGVARMT C



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y217-1-unknown MEHIRT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y217-1-unknown MEHIRT... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81755

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ARMTC 621 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)