Q9Y281: Cofilin-2

General Information

Protein names	- Cofilin-2 - Cofilin, muscle isoform
Gene names	CFL2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y281

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI
        70         80         90        100        110        120
GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS
       130        140        150        160
KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL

Isoforms

- Isoform 3 of Cofilin-2

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y281-2-unknown	MASGVT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y281-2-Acetylation	ASGVTV...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y281-2-Acetylation	ASGVTV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9Y281-2-Acetylation	ASGVTV...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9Y281-2-Acetylation	ASGVTV...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9Y281-18-unknown	MKVRKS...	18		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71365

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...EGKPL	166	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...EGKPL	166	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66983
...EGKPL	166		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...EGKPL	166		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)