TopFIND 4.0

Q9Y297: F-box/WD repeat-containing protein 1A

General Information

Protein names
- F-box/WD repeat-containing protein 1A
- E3RSIkappaB
- Epididymis tissue protein Li 2a
- F-box and WD repeats protein beta-TrCP
- pIkappaBalpha-E3 receptor subunit
Gene names BTRC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y297

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDPAEAVLQE KALKFMCSMP RSLWLGCSSL ADSMPSLRCL YNPGTGALTA FQNSSEREDC 
        70         80         90        100        110        120 
NNGEPPRKII PEKNSLRQTY NSCARLCLNQ ETVCLASTAM KTENCVAKTK LANGTSSMIV 
       130        140        150        160        170        180 
PKQRKLSASY EKEKELCVKY FEQWSESDQV EFVEHLISQM CHYQHGHINS YLKPMLQRDF 
       190        200        210        220        230        240 
ITALPARGLD HIAENILSYL DAKSLCAAEL VCKEWYRVTS DGMLWKKLIE RMVRTDSLWR 
       250        260        270        280        290        300 
GLAERRGWGQ YLFKNKPPDG NAPPNSFYRA LYPKIIQDIE TIESNWRCGR HSLQRIHCRS 
       310        320        330        340        350        360 
ETSKGVYCLQ YDDQKIVSGL RDNTIKIWDK NTLECKRILT GHTGSVLCLQ YDERVIITGS 
       370        380        390        400        410        420 
SDSTVRVWDV NTGEMLNTLI HHCEAVLHLR FNNGMMVTCS KDRSIAVWDM ASPTDITLRR 
       430        440        450        460        470        480 
VLVGHRAAVN VVDFDDKYIV SASGDRTIKV WNTSTCEFVR TLNGHKRGIA CLQYRDRLVV 
       490        500        510        520        530        540 
SGSSDNTIRL WDIECGACLR VLEGHEELVR CIRFDNKRIV SGAYDGKIKV WDLVAALDPR 
       550        560        570        580        590        600 
APAGTLCLRT LVEHSGRVFR LQFDEFQIVS SSHDDTILIW DFLNDPAAQA EPPRSPSRTY 
   
TYISR

Isoforms

- Isoform 2 of F-box/WD repeat-containing protein 1A

Sequence View

        10         20         30         40         50         60 
MDPAEAVLQE KALKFMCSMP RSLWLGCSSL ADSMPSLRCL YNPGTGALTA FQNSSEREDC 
        70         80         90        100        110        120 
NNGEPPRKII PEKNSLRQTY NSCARLCLNQ ETVCLASTAM KTENCVAKTK LANGTSSMIV 
       130        140        150        160        170        180 
PKQRKLSASY EKEKELCVKY FEQWSESDQV EFVEHLISQM CHYQHGHINS YLKPMLQRDF 
       190        200        210        220        230        240 
ITALPARGLD HIAENILSYL DAKSLCAAEL VCKEWYRVTS DGMLWKKLIE RMVRTDSLWR 
       250        260        270        280        290        300 
GLAERRGWGQ YLFKNKPPDG NAPPNSFYRA LYPKIIQDIE TIESNWRCGR HSLQRIHCRS 
       310        320        330        340        350        360 
ETSKGVYCLQ YDDQKIVSGL RDNTIKIWDK NTLECKRILT GHTGSVLCLQ YDERVIITGS 
       370        380        390        400        410        420 
SDSTVRVWDV NTGEMLNTLI HHCEAVLHLR FNNGMMVTCS KDRSIAVWDM ASPTDITLRR 
       430        440        450        460        470        480 
VLVGHRAAVN VVDFDDKYIV SASGDRTIKV WNTSTCEFVR TLNGHKRGIA CLQYRDRLVV 
       490        500        510        520        530        540 
SGSSDNTIRL WDIECGACLR VLEGHEELVR CIRFDNKRIV SGAYDGKIKV WDLVAALDPR 
       550        560        570        580        590        600 
APAGTLCLRT LVEHSGRVFR LQFDEFQIVS SSHDDTILIW DFLNDPAAQA EPPRSPSRTY 
   
TYISR



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y297-1-unknown MDPAEA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TYISR 605 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TYISR 605 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70500

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)