TopFIND 4.0

Q9Y2E6: E3 ubiquitin-protein ligase DTX4

General Information

Protein names
- E3 ubiquitin-protein ligase DTX4
- 2.3.2.27 {ECO:0000250|UniProtKB:Q61010}
- Protein deltex-4
- Deltex4
- RING finger protein 155
- RING-type E3 ubiquitin transferase DTX4 {ECO:0000305}
Gene names DTX4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y2E6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLLASAVVVW EWLNEHGRWR PYSPAVSHHI EAVVRAGPRA GGSVVLGQVD SRLAPYIIDL 
        70         80         90        100        110        120 
QSMNQFRQDT GTLRPVRRNY YDPSSAPGKG VVWEWENDNG SWTPYDMEVG ITIQHAYEKQ 
       130        140        150        160        170        180 
HPWIDLTSIG FSYVIDFNTM GQINRQTQRQ RRVRRRLDLI YPMVTGTLPK AQSWPVSPGP 
       190        200        210        220        230        240 
ATSPPMSPCS CPQCVLVMSV KAAVVNGSTG PLQLPVTRKN MPPPGVVKLP PLPGSGAKPL 
       250        260        270        280        290        300 
DSTGTIRGPL KTAPSQVIRR QASSMPTGTT MGSPASPPGP NSKTGRVALA TLNRTNLQRL 
       310        320        330        340        350        360 
AIAQSRVLIA SGVPTVPVKN LNGSSPVNPA LAGITGILMS AAGLPVCLTR PPKLVLHPPP 
       370        380        390        400        410        420 
VSKSEIKSIP GVSNTSRKTT KKQAKKGKTP EEVLKKYLQK VRHPPDEDCT ICMERLTAPS 
       430        440        450        460        470        480 
GYKGPQPTVK PDLVGKLSRC GHVYHIYCLV AMYNNGNKDG SLQCPTCKTI YGVKTGTQPP 
       490        500        510        520        530        540 
GKMEYHLIPH SLPGHPDCKT IRIIYSIPPG IQGPEHPNPG KSFSARGFPR HCYLPDSEKG 
       550        560        570        580        590        600 
RKVLKLLLVA WDRRLIFAIG TSSTTGESDT VIWNEVHHKT EFGSNLTGHG YPDANYLDNV 
       610    
LAELAAQGIS EDSTAQEKD

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase DTX4

Sequence View

        10         20         30         40         50         60 
MLLASAVVVW EWLNEHGRWR PYSPAVSHHI EAVVRAGPRA GGSVVLGQVD SRLAPYIIDL 
        70         80         90        100        110        120 
QSMNQFRQDT GTLRPVRRNY YDPSSAPGKG VVWEWENDNG SWTPYDMEVG ITIQHAYEKQ 
       130        140        150        160        170        180 
HPWIDLTSIG FSYVIDFNTM GQINRQTQRQ RRVRRRLDLI YPMVTGTLPK AQSWPVSPGP 
       190        200        210        220        230        240 
ATSPPMSPCS CPQCVLVMSV KAAVVNGSTG PLQLPVTRKN MPPPGVVKLP PLPGSGAKPL 
       250        260        270        280        290        300 
DSTGTIRGPL KTAPSQVIRR QASSMPTGTT MGSPASPPGP NSKTGRVALA TLNRTNLQRL 
       310        320        330        340        350        360 
AIAQSRVLIA SGVPTVPVKN LNGSSPVNPA LAGITGILMS AAGLPVCLTR PPKLVLHPPP 
       370        380        390        400        410        420 
VSKSEIKSIP GVSNTSRKTT KKQAKKGKTP EEVLKKYLQK VRHPPDEDCT ICMERLTAPS 
       430        440        450        460        470        480 
GYKGPQPTVK PDLVGKLSRC GHVYHIYCLV AMYNNGNKDG SLQCPTCKTI YGVKTGTQPP 
       490        500        510        520        530        540 
GKMEYHLIPH SLPGHPDCKT IRIIYSIPPG IQGPEHPNPG KSFSARGFPR HCYLPDSEKG 
       550        560        570        580        590        600 
RKVLKLLLVA WDRRLIFAIG TSSTTGESDT VIWNEVHHKT EFGSNLTGHG YPDANYLDNV 
       610    
LAELAAQGIS EDSTAQEKD



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y2E6-1-unknown MLLASA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y2E6-107-unknown MEVGIT... 107 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73340

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AQEKD 619 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AQEKD 619 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt68958

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)