TopFIND 4.0

Q9Y2G5: GDP-fucose protein O-fucosyltransferase 2

General Information

Protein names
- GDP-fucose protein O-fucosyltransferase 2
- 2.4.1.221
- Peptide-O-fucosyltransferase 2
- O-FucT-2
Gene names POFUT2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9Y2G5

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATLSFVFLL LGAVSWPPAS ASGQEFWPGQ SAADILSGAA SRRRYLLYDV NPPEGFNLRR 
        70         80         90        100        110        120 
DVYIRIASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV RIPWSEFFDL PSLNKNIPVI 
       130        140        150        160        170        180 
EYEQFIAESG GPFIDQVYVL QSYAEGWKEG TWEEKVDERP CIDQLLYSQD KHEYYRGWFW 
       190        200        210        220        230        240 
GYEETRGLNV SCLSVQGSAS IVAPLLLRNT SARSVMLDRA ENLLHDHYGG KEYWDTRRSM 
       250        260        270        280        290        300 
VFARHLREVG DEFRSRHLNS TDDADRIPFQ EDWMKMKVKL GSALGGPYLG VHLRRKDFIW 
       310        320        330        340        350        360 
GHRQDVPSLE GAVRKIRSLM KTHRLDKVFV ATDAVRKEYE ELKKLLPEMV RFEPTWEELE 
       370        380        390        400        410        420 
LYKDGGVAII DQWICAHARF FIGTSVSTFS FRIHEEREIL GLDPKTTYNR FCGDQEKACE 
   
QPTHWKITY

Isoforms

- Isoform A of GDP-fucose protein O-fucosyltransferase 2 - Isoform B of GDP-fucose protein O-fucosyltransferase 2

Sequence View

        10         20         30         40         50         60 
MATLSFVFLL LGAVSWPPAS ASGQEFWPGQ SAADILSGAA SRRRYLLYDV NPPEGFNLRR 
        70         80         90        100        110        120 
DVYIRIASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV RIPWSEFFDL PSLNKNIPVI 
       130        140        150        160        170        180 
EYEQFIAESG GPFIDQVYVL QSYAEGWKEG TWEEKVDERP CIDQLLYSQD KHEYYRGWFW 
       190        200        210        220        230        240 
GYEETRGLNV SCLSVQGSAS IVAPLLLRNT SARSVMLDRA ENLLHDHYGG KEYWDTRRSM 
       250        260        270        280        290        300 
VFARHLREVG DEFRSRHLNS TDDADRIPFQ EDWMKMKVKL GSALGGPYLG VHLRRKDFIW 
       310        320        330        340        350        360 
GHRQDVPSLE GAVRKIRSLM KTHRLDKVFV ATDAVRKEYE ELKKLLPEMV RFEPTWEELE 
       370        380        390        400        410        420 
LYKDGGVAII DQWICAHARF FIGTSVSTFS FRIHEEREIL GLDPKTTYNR FCGDQEKACE 
   
QPTHWKITY         10         20         30         40         50         60 
MATLSFVFLL LGAVSWPPAS ASGQEFWPGQ SAADILSGAA SRRRYLLYDV NPPEGFNLRR 
        70         80         90        100        110        120 
DVYIRIASLL KTLLKTEEWV LVLPPWGRLY HWQSPDIHQV RIPWSEFFDL PSLNKNIPVI 
       130        140        150        160        170        180 
EYEQFIAESG GPFIDQVYVL QSYAEGWKEG TWEEKVDERP CIDQLLYSQD KHEYYRGWFW 
       190        200        210        220        230        240 
GYEETRGLNV SCLSVQGSAS IVAPLLLRNT SARSVMLDRA ENLLHDHYGG KEYWDTRRSM 
       250        260        270        280        290        300 
VFARHLREVG DEFRSRHLNS TDDADRIPFQ EDWMKMKVKL GSALGGPYLG VHLRRKDFIW 
       310        320        330        340        350        360 
GHRQDVPSLE GAVRKIRSLM KTHRLDKVFV ATDAVRKEYE ELKKLLPEMV RFEPTWEELE 
       370        380        390        400        410        420 
LYKDGGVAII DQWICAHARF FIGTSVSTFS FRIHEEREIL GLDPKTTYNR FCGDQEKACE 
   
QPTHWKITY



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Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9Y2G5-1-unknown MATLSF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83718
    Q9Y2G5-22-unknown SGQEFW... 22 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9Y2G5-22-unknown SGQEFW... 22 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt112824

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...WKITY 429 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)