Q9Y2W7: Calsenilin

General Information

Protein names	- Calsenilin - A-type potassium channel modulatory protein 3 - DRE-antagonist modulator - DREAM - Kv channel-interacting protein 3 - KChIP3
Gene names	KCNIP3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y2W7

2 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Calsenilin - Isoform 3 of Calsenilin

Sequence View

        10         20         30         40         50         60
MQPAKEVTKA SDGSLLGDLG HTPLSKKEGI KWQRPRLSRQ ALMRCCLVKW ILSSTAPQGS
        70         80         90        100        110        120
DSSDSELELS TVRHQPEGLD QLQAQTKFTK KELQSLYRGF KNECPTGLVD EDTFKLIYAQ
       130        140        150        160        170        180
FFPQGDATTY AHFLFNAFDA DGNGAIHFED FVVGLSILLR GTVHEKLKWA FNLYDINKDG
       190        200        210        220        230        240
YITKEEMLAI MKSIYDMMGR HTYPILREDA PAEHVERFFE KMDRNQDGVV TIEEFLEACQ
       250
KDENIMSSMQ LFENVI         10         20         30         40         50         60
MQPAKEVTKA SDGSLLGDLG HTPLSKKEGI KWQRPRLSRQ ALMRCCLVKW ILSSTAPQGS
        70         80         90        100        110        120
DSSDSELELS TVRHQPEGLD QLQAQTKFTK KELQSLYRGF KNECPTGLVD EDTFKLIYAQ
       130        140        150        160        170        180
FFPQGDATTY AHFLFNAFDA DGNGAIHFED FVVGLSILLR GTVHEKLKWA FNLYDINKDG
       190        200        210        220        230        240
YITKEEMLAI MKSIYDMMGR HTYPILREDA PAEHVERFFE KMDRNQDGVV TIEEFLEACQ
       250
KDENIMSSMQ LFENVI

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y2W7-1-unknown	MQPAKE...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y2W7-1-unknown	MQPAKE...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt71846
Q9Y2W7-65-unknown	SELELS...	65	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2358
Q9Y2W7-65-unknown	SELELS...	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt140278
Q9Y2W7-65-unknown	SELELS...	65	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196420

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SDSSDS	64	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2358
...SDSSDS	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt123400
...FENVI	256	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FENVI	256	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67465
...FENVI	256	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt67464

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CASP3_HUMAN	64	SSDS.\|.SELE	inferred from experiment	unknown	MEROPS	Wasco W	Choi EK et al.:Calsenilin is a substrate for c... (C14.003)	11278424,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)