Q9Y305: Acyl-coenzyme A thioesterase 9, mitochondrial

General Information

Protein names	- Acyl-coenzyme A thioesterase 9, mitochondrial - Acyl-CoA thioesterase 9 - 3.1.2.- - Acyl-CoA thioester hydrolase 9
Gene names	ACOT9
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y305

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Acyl-coenzyme A thioesterase 9, mitochondrial - Isoform 3 of Acyl-coenzyme A thioesterase 9, mitochondrial - Isoform 4 of Acyl-coenzyme A thioesterase 9, mitochondrial

Sequence View

        10         20         30         40         50         60
MRRAALRLCA LGKGQLTPGR GLTQGPQNPK KQGIFHIHEV RDKLREIVGA STNWRDHVKA
        70         80         90        100        110        120
MEERKLLHSF LAKSQDGLPP RRMKDSYIEV LLPLGSEPEL REKYLTVQNT VRFGRILEDL
       130        140        150        160        170        180
DSLGVLICYM HNKIHSAKMS PLSIVTALVD KIDMCKKSLS PEQDIKFSGH VSWVGKTSME
       190        200        210        220        230        240
VKMQMFQLHG DEFCPVLDAT FVMVARDSEN KGPAFVNPLI PESPEEEELF RQGELNKGRR
       250        260        270        280        290        300
IAFSSTSLLK MAPSAEERTT IHEMFLSTLD PKTISFRSRV LPSNAVWMEN SKLKSLEICH
       310        320        330        340        350        360
PQERNIFNRI FGGFLMRKAY ELAWATACSF GGSRPFVVAV DDIMFQKPVE VGSLLFLSSQ
       370        380        390        400        410        420
VCFTQNNYIQ VRVHSEVASL QEKQHTTTNV FHFTFMSEKE VPLVFPKTYG ESMLYLDGQR
       430
HFNSMSGPAT LRKDYLVEP         10         20         30         40         50         60
MRRAALRLCA LGKGQLTPGR GLTQGPQNPK KQGIFHIHEV RDKLREIVGA STNWRDHVKA
        70         80         90        100        110        120
MEERKLLHSF LAKSQDGLPP RRMKDSYIEV LLPLGSEPEL REKYLTVQNT VRFGRILEDL
       130        140        150        160        170        180
DSLGVLICYM HNKIHSAKMS PLSIVTALVD KIDMCKKSLS PEQDIKFSGH VSWVGKTSME
       190        200        210        220        230        240
VKMQMFQLHG DEFCPVLDAT FVMVARDSEN KGPAFVNPLI PESPEEEELF RQGELNKGRR
       250        260        270        280        290        300
IAFSSTSLLK MAPSAEERTT IHEMFLSTLD PKTISFRSRV LPSNAVWMEN SKLKSLEICH
       310        320        330        340        350        360
PQERNIFNRI FGGFLMRKAY ELAWATACSF GGSRPFVVAV DDIMFQKPVE VGSLLFLSSQ
       370        380        390        400        410        420
VCFTQNNYIQ VRVHSEVASL QEKQHTTTNV FHFTFMSEKE VPLVFPKTYG ESMLYLDGQR
       430
HFNSMSGPAT LRKDYLVEP         10         20         30         40         50         60
MRRAALRLCA LGKGQLTPGR GLTQGPQNPK KQGIFHIHEV RDKLREIVGA STNWRDHVKA
        70         80         90        100        110        120
MEERKLLHSF LAKSQDGLPP RRMKDSYIEV LLPLGSEPEL REKYLTVQNT VRFGRILEDL
       130        140        150        160        170        180
DSLGVLICYM HNKIHSAKMS PLSIVTALVD KIDMCKKSLS PEQDIKFSGH VSWVGKTSME
       190        200        210        220        230        240
VKMQMFQLHG DEFCPVLDAT FVMVARDSEN KGPAFVNPLI PESPEEEELF RQGELNKGRR
       250        260        270        280        290        300
IAFSSTSLLK MAPSAEERTT IHEMFLSTLD PKTISFRSRV LPSNAVWMEN SKLKSLEICH
       310        320        330        340        350        360
PQERNIFNRI FGGFLMRKAY ELAWATACSF GGSRPFVVAV DDIMFQKPVE VGSLLFLSSQ
       370        380        390        400        410        420
VCFTQNNYIQ VRVHSEVASL QEKQHTTTNV FHFTFMSEKE VPLVFPKTYG ESMLYLDGQR
       430
HFNSMSGPAT LRKDYLVEP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y305-1-unknown	MRRAAL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66183
Q9Y305-22-unknown	LTQGPQ...	22	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y305-22-unknown	LTQGPQ...	22	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
Q9Y305-23-	TQGPQN...	23		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9Y305-23-	TQGPQN...	23		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y305-61-unknown	MEERKL...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt66182
Q9Y305-61-unknown	MEERKL...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103474
Q9Y305-61-unknown	MEERKL...	61	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt103473

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...PLVFPK	406		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PLVFPK	406		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...PLVFPK	406	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt143054
...PLVFPK	406	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt143055
...PLVFPK	406	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt143053
...PLVFPK	406		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...PLVFPK	406		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...YLVEP	439	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...YLVEP	439	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61800
...YLVEP	439	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61799
...YLVEP	439	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61801

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)