Q9Y3E7: Charged multivesicular body protein 3

General Information

Protein names	- Charged multivesicular body protein 3 - Chromatin-modifying protein 3 - Neuroendocrine differentiation factor - Vacuolar protein sorting-associated protein 24 - hVps24
Gene names	CHMP3
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y3E7

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Charged multivesicular body protein 3 - Isoform 3 of Charged multivesicular body protein 3 - Isoform 4 of Charged multivesicular body protein 3

Sequence View

        10         20         30         40         50         60
MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC
        70         80         90        100        110        120
IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI
       130        140        150        160        170        180
PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA
       190        200        210        220
PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS         10         20         30         40         50         60
MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC
        70         80         90        100        110        120
IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI
       130        140        150        160        170        180
PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA
       190        200        210        220
PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS         10         20         30         40         50         60
MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC
        70         80         90        100        110        120
IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI
       130        140        150        160        170        180
PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA
       190        200        210        220
PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y3E7-1-unknown	MGLFGK...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70583
Q9Y3E7-2-unknown	GLFGKT...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y3E7-2-unknown	GLFGKT...	2		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y3E7-2-unknown	GLFGKT...	2		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y3E7-2-unknown	GLFGKT...	2	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110404
Q9Y3E7-2-	GLFGKT...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9Y3E7-2-	GLFGKT...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9Y3E7-2-	GLFGKT...	2		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y3E7-67-unknown	MIRSRK...	67	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt70581
Q9Y3E7-67-unknown	MIRSRK...	67	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106011

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATLRS	222	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...ATLRS	222	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66199
...ATLRS	222	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66201
...ATLRS	222	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt66200

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)