Q9Y3Q0: N-acetylated-alpha-linked acidic dipeptidase 2

General Information

Protein names	- N-acetylated-alpha-linked acidic dipeptidase 2 - 3.4.17.21 - Glutamate carboxypeptidase III - GCPIII - N-acetylated-alpha-linked acidic dipeptidase II - NAALADase II
Gene names	NAALAD2
Organism	Homo sapiens
Protease Family
Protease ID	M28.012
Chromosome location
UniProt ID	Q9Y3Q0

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAESRGRLYL WMCLAAALAS FLMGFMVGWF IKPLKETTTS VRYHQSIRWK LVSEMKAENI
        70         80         90        100        110        120
KSFLRSFTKL PHLAGTEQNF LLAKKIQTQW KKFGLDSAKL VHYDVLLSYP NETNANYISI
       130        140        150        160        170        180
VDEHETEIFK TSYLEPPPDG YENVTNIVPP YNAFSAQGMP EGDLVYVNYA RTEDFFKLER
       190        200        210        220        230        240
EMGINCTGKI VIARYGKIFR GNKVKNAMLA GAIGIILYSD PADYFAPEVQ PYPKGWNLPG
       250        260        270        280        290        300
TAAQRGNVLN LNGAGDPLTP GYPAKEYTFR LDVEEGVGIP RIPVHPIGYN DAEILLRYLG
       310        320        330        340        350        360
GIAPPDKSWK GALNVSYSIG PGFTGSDSFR KVRMHVYNIN KITRIYNVVG TIRGSVEPDR
       370        380        390        400        410        420
YVILGGHRDS WVFGAIDPTS GVAVLQEIAR SFGKLMSKGW RPRRTIIFAS WDAEEFGLLG
       430        440        450        460        470        480
STEWAEENVK ILQERSIAYI NSDSSIEGNY TLRVDCTPLL YQLVYKLTKE IPSPDDGFES
       490        500        510        520        530        540
KSLYESWLEK DPSPENKNLP RINKLGSGSD FEAYFQRLGI ASGRARYTKN KKTDKYSSYP
       550        560        570        580        590        600
VYHTIYETFE LVEKFYDPTF KKQLSVAQLR GALVYELVDS KIIPFNIQDY AEALKNYAAS
       610        620        630        640        650        660
IYNLSKKHDQ QLTDHGVSFD SLFSAVKNFS EAASDFHKRL IQVDLNNPIA VRMMNDQLML
       670        680        690        700        710        720
LERAFIDPLG LPGKLFYRHI IFAPSSHNKY AGESFPGIYD AIFDIENKAN SRLAWKEVKK
       730        740
HISIAAFTIQ AAAGTLKEVL

Isoforms

- Isoform 2 of N-acetylated-alpha-linked acidic dipeptidase 2

Sequence View

        10         20         30         40         50         60
MAESRGRLYL WMCLAAALAS FLMGFMVGWF IKPLKETTTS VRYHQSIRWK LVSEMKAENI
        70         80         90        100        110        120
KSFLRSFTKL PHLAGTEQNF LLAKKIQTQW KKFGLDSAKL VHYDVLLSYP NETNANYISI
       130        140        150        160        170        180
VDEHETEIFK TSYLEPPPDG YENVTNIVPP YNAFSAQGMP EGDLVYVNYA RTEDFFKLER
       190        200        210        220        230        240
EMGINCTGKI VIARYGKIFR GNKVKNAMLA GAIGIILYSD PADYFAPEVQ PYPKGWNLPG
       250        260        270        280        290        300
TAAQRGNVLN LNGAGDPLTP GYPAKEYTFR LDVEEGVGIP RIPVHPIGYN DAEILLRYLG
       310        320        330        340        350        360
GIAPPDKSWK GALNVSYSIG PGFTGSDSFR KVRMHVYNIN KITRIYNVVG TIRGSVEPDR
       370        380        390        400        410        420
YVILGGHRDS WVFGAIDPTS GVAVLQEIAR SFGKLMSKGW RPRRTIIFAS WDAEEFGLLG
       430        440        450        460        470        480
STEWAEENVK ILQERSIAYI NSDSSIEGNY TLRVDCTPLL YQLVYKLTKE IPSPDDGFES
       490        500        510        520        530        540
KSLYESWLEK DPSPENKNLP RINKLGSGSD FEAYFQRLGI ASGRARYTKN KKTDKYSSYP
       550        560        570        580        590        600
VYHTIYETFE LVEKFYDPTF KKQLSVAQLR GALVYELVDS KIIPFNIQDY AEALKNYAAS
       610        620        630        640        650        660
IYNLSKKHDQ QLTDHGVSFD SLFSAVKNFS EAASDFHKRL IQVDLNNPIA VRMMNDQLML
       670        680        690        700        710        720
LERAFIDPLG LPGKLFYRHI IFAPSSHNKY AGESFPGIYD AIFDIENKAN SRLAWKEVKK
       730        740
HISIAAFTIQ AAAGTLKEVL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y3Q0-1-unknown	MAESRG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y3Q0-1-unknown	MAESRG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt82232
Q9Y3Q0-55-unknown	MKAENI...	55	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435670
Q9Y3Q0-55-unknown	MKAENI...	55	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt129944

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KKIQTQ	88	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431989
...KKIQTQ	88	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt108646
...QGMPEG	161	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435670
...QGMPEG	161	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt108648
...LKEVL	740	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

TopFIND

Q9Y3Q0: N-acetylated-alpha-linked acidic dipeptidase 2

General Information

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates