Q9Y468: Lethal(3)malignant brain tumor-like protein 1

General Information

Protein names	- Lethal(3)malignant brain tumor-like protein 1 - H-l(3)mbt - H-l(3)mbt protein - L(3)mbt-like - L(3)mbt protein homolog - L3MBTL1
Gene names	L3MBTL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y468

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Lethal(3)malignant brain tumor-like protein 1 - Isoform 2 of Lethal(3)malignant brain tumor-like protein 1 - Isoform 3 of Lethal(3)malignant brain tumor-like protein 1 - Isoform 5 of Lethal(3)malignant brain tumor-like protein 1 - Isoform 4 of Lethal(3)malignant brain tumor-like protein 1

Sequence View

        10         20         30         40         50         60
MHLVAGDSPG SGPHLPATAF IIPASSATLG LPSSALDVSC FPREPIHVGA PEQVAGCEPV
        70         80         90        100        110        120
SATVLPQLSA GPASSSTSTV RLLEWTEAAA PPPGGGLRFR ISEYKPLNMA GVEQPPSPEL
       130        140        150        160        170        180
RQEGVTEYED GGAPAGDGEA GPQQAEDHPQ NPPEDPNQDP PEDDSTCQCQ ACGPHQAAGP
       190        200        210        220        230        240
DLGSSNDGCP QLFQERSVIV ENSSGSTSAS ELLKPMKKRK RREYQSPSEE ESEPEAMEKQ
       250        260        270        280        290        300
EEGKDPEGQP TASTPESEEW SSSQPATGEK KECWSWESYL EEQKAITAPV SLFQDSQAVT
       310        320        330        340        350        360
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
       370        380        390        400        410        420
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
       430        440        450        460        470        480
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDP SSPYIHPVGW CQKQGKPLTP
       490        500        510        520        530        540
PQDYPDPDNF CWEKYLEETG ASAVPTWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
       550        560        570        580        590        600
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLGPRE PSSASPGGCP
       610        620        630        640        650        660
PLSYRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
       670        680        690        700        710        720
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDVVH QSLFMSALSA
       730        740        750        760        770        780
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEARIV
       790        800        810        820        830        840
RVTHVSGKTL VWTVAQLGDL VCSDHLQEGK GILETGVHSL LCSLPTHLLA KLSFASDSQY

        10         20         30         40         50         60
MHLVAGDSPG SGPHLPATAF IIPASSATLG LPSSALDVSC FPREPIHVGA PEQVAGCEPV
        70         80         90        100        110        120
SATVLPQLSA GPASSSTSTV RLLEWTEAAA PPPGGGLRFR ISEYKPLNMA GVEQPPSPEL
       130        140        150        160        170        180
RQEGVTEYED GGAPAGDGEA GPQQAEDHPQ NPPEDPNQDP PEDDSTCQCQ ACGPHQAAGP
       190        200        210        220        230        240
DLGSSNDGCP QLFQERSVIV ENSSGSTSAS ELLKPMKKRK RREYQSPSEE ESEPEAMEKQ
       250        260        270        280        290        300
EEGKDPEGQP TASTPESEEW SSSQPATGEK KECWSWESYL EEQKAITAPV SLFQDSQAVT
       310        320        330        340        350        360
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
       370        380        390        400        410        420
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
       430        440        450        460        470        480
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDP SSPYIHPVGW CQKQGKPLTP
       490        500        510        520        530        540
PQDYPDPDNF CWEKYLEETG ASAVPTWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
       550        560        570        580        590        600
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLGPRE PSSASPGGCP
       610        620        630        640        650        660
PLSYRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
       670        680        690        700        710        720
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDVVH QSLFMSALSA
       730        740        750        760        770        780
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEARIV
       790        800        810        820        830        840
RVTHVSGKTL VWTVAQLGDL VCSDHLQEGK GILETGVHSL LCSLPTHLLA KLSFASDSQY

        10         20         30         40         50         60
MHLVAGDSPG SGPHLPATAF IIPASSATLG LPSSALDVSC FPREPIHVGA PEQVAGCEPV
        70         80         90        100        110        120
SATVLPQLSA GPASSSTSTV RLLEWTEAAA PPPGGGLRFR ISEYKPLNMA GVEQPPSPEL
       130        140        150        160        170        180
RQEGVTEYED GGAPAGDGEA GPQQAEDHPQ NPPEDPNQDP PEDDSTCQCQ ACGPHQAAGP
       190        200        210        220        230        240
DLGSSNDGCP QLFQERSVIV ENSSGSTSAS ELLKPMKKRK RREYQSPSEE ESEPEAMEKQ
       250        260        270        280        290        300
EEGKDPEGQP TASTPESEEW SSSQPATGEK KECWSWESYL EEQKAITAPV SLFQDSQAVT
       310        320        330        340        350        360
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
       370        380        390        400        410        420
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
       430        440        450        460        470        480
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDP SSPYIHPVGW CQKQGKPLTP
       490        500        510        520        530        540
PQDYPDPDNF CWEKYLEETG ASAVPTWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
       550        560        570        580        590        600
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLGPRE PSSASPGGCP
       610        620        630        640        650        660
PLSYRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
       670        680        690        700        710        720
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDVVH QSLFMSALSA
       730        740        750        760        770        780
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEARIV
       790        800        810        820        830        840
RVTHVSGKTL VWTVAQLGDL VCSDHLQEGK GILETGVHSL LCSLPTHLLA KLSFASDSQY

        10         20         30         40         50         60
MHLVAGDSPG SGPHLPATAF IIPASSATLG LPSSALDVSC FPREPIHVGA PEQVAGCEPV
        70         80         90        100        110        120
SATVLPQLSA GPASSSTSTV RLLEWTEAAA PPPGGGLRFR ISEYKPLNMA GVEQPPSPEL
       130        140        150        160        170        180
RQEGVTEYED GGAPAGDGEA GPQQAEDHPQ NPPEDPNQDP PEDDSTCQCQ ACGPHQAAGP
       190        200        210        220        230        240
DLGSSNDGCP QLFQERSVIV ENSSGSTSAS ELLKPMKKRK RREYQSPSEE ESEPEAMEKQ
       250        260        270        280        290        300
EEGKDPEGQP TASTPESEEW SSSQPATGEK KECWSWESYL EEQKAITAPV SLFQDSQAVT
       310        320        330        340        350        360
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
       370        380        390        400        410        420
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
       430        440        450        460        470        480
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDP SSPYIHPVGW CQKQGKPLTP
       490        500        510        520        530        540
PQDYPDPDNF CWEKYLEETG ASAVPTWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
       550        560        570        580        590        600
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLGPRE PSSASPGGCP
       610        620        630        640        650        660
PLSYRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
       670        680        690        700        710        720
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDVVH QSLFMSALSA
       730        740        750        760        770        780
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEARIV
       790        800        810        820        830        840
RVTHVSGKTL VWTVAQLGDL VCSDHLQEGK GILETGVHSL LCSLPTHLLA KLSFASDSQY

        10         20         30         40         50         60
MHLVAGDSPG SGPHLPATAF IIPASSATLG LPSSALDVSC FPREPIHVGA PEQVAGCEPV
        70         80         90        100        110        120
SATVLPQLSA GPASSSTSTV RLLEWTEAAA PPPGGGLRFR ISEYKPLNMA GVEQPPSPEL
       130        140        150        160        170        180
RQEGVTEYED GGAPAGDGEA GPQQAEDHPQ NPPEDPNQDP PEDDSTCQCQ ACGPHQAAGP
       190        200        210        220        230        240
DLGSSNDGCP QLFQERSVIV ENSSGSTSAS ELLKPMKKRK RREYQSPSEE ESEPEAMEKQ
       250        260        270        280        290        300
EEGKDPEGQP TASTPESEEW SSSQPATGEK KECWSWESYL EEQKAITAPV SLFQDSQAVT
       310        320        330        340        350        360
HNKNGFKLGM KLEGIDPQHP SMYFILTVAE VCGYRLRLHF DGYSECHDFW VNANSPDIHP
       370        380        390        400        410        420
AGWFEKTGHK LQPPKGYKEE EFSWSQYLRS TRAQAAPKHL FVSQSHSPPP LGFQVGMKLE
       430        440        450        460        470        480
AVDRMNPSLV CVASVTDVVD SRFLVHFDNW DDTYDYWCDP SSPYIHPVGW CQKQGKPLTP
       490        500        510        520        530        540
PQDYPDPDNF CWEKYLEETG ASAVPTWAFK VRPPHSFLVN MKLEAVDRRN PALIRVASVE
       550        560        570        580        590        600
DVEDHRIKIH FDGWSHGYDF WIDADHPDIH PAGWCSKTGH PLQPPLGPRE PSSASPGGCP
       610        620        630        640        650        660
PLSYRSLPHT RTSKYSFHHR KCPTPGCDGS GHVTGKFTAH HCLSGCPLAE RNQSRLKAEL
       670        680        690        700        710        720
SDSEASARKK NLSGFSPRKK PRHHGRIGRP PKYRKIPQED FQTLTPDVVH QSLFMSALSA
       730        740        750        760        770        780
HPDRSLSVCW EQHCKLLPGV AGISASTVAK WTIDEVFGFV QTLTGCEDQA RLFKDEARIV
       790        800        810        820        830        840
RVTHVSGKTL VWTVAQLGDL VCSDHLQEGK GILETGVHSL LCSLPTHLLA KLSFASDSQY

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9Y468-1-unknown	MHLVAG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9Y468-1-unknown	MHLVAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79709
Q9Y468-1-unknown	MHLVAG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79711
Q9Y468-41-unknown	FPREPI...	41	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415971
Q9Y468-41-unknown	FPREPI...	41	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195901
Q9Y468-41-unknown	FPREPI...	41	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195900
Q9Y468-215-unknown	PMKKRK...	215	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000410139
Q9Y468-215-unknown	PMKKRK...	215	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198180
Q9Y468-215-unknown	PMKKRK...	215	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198179
Q9Y468-349-unknown	FWVNAN...	349	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt79710
Q9Y468-349-unknown	FWVNAN...	349	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101235
Q9Y468-349-unknown	FWVNAN...	349	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101234

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PQLSAG	70	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387971
...PQLSAG	70	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154046
...PQLSAG	70	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154045
...LRQEGV	124	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000415971
...LRQEGV	124	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154661
...LRQEGV	124	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154660
...VAKWTI	752	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)