Q9Y483: Metal-response element-binding transcription factor 2

General Information

Protein names	- Metal-response element-binding transcription factor 2 - Metal regulatory transcription factor 2 - Metal-response element DNA-binding protein M96 - Polycomb-like protein 2 - hPCl2
Gene names	MTF2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y483

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Metal-response element-binding transcription factor 2 - Isoform 3 of Metal-response element-binding transcription factor 2 - Isoform 4 of Metal-response element-binding transcription factor 2 - Isoform 3 of Metal-response element-binding transcription factor 2 - Isoform 4 of Metal-response element-binding transcription factor 2

Sequence View

        10         20         30         40         50         60
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL
        70         80         90        100        110        120
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV
       130        140        150        160        170        180
ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ
       190        200        210        220        230        240
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF
       250        260        270        280        290        300
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
       310        320        330        340        350        360
DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEIKKK KHLFGLRIRV PPVPPNVAFK
       370        380        390        400        410        420
AEKEPEGTSH EFKIKGRKAS KPISDSREVS NGIEKKGKKK SVGRPPGPYT RKMIQKTAEP
       430        440        450        460        470        480
LLDKESISEN PTLDLPCSIG RTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR
       490        500        510        520        530        540
KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE GKEDYQFDEL NTEILNNLAD
       550        560        570        580        590
QELQLNHLKN SITSYFGAAG RIACGEKYRV LARRVTLDGK VQYLVEWEGA TAS         10         20         30         40         50         60
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL
        70         80         90        100        110        120
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV
       130        140        150        160        170        180
ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ
       190        200        210        220        230        240
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF
       250        260        270        280        290        300
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
       310        320        330        340        350        360
DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEIKKK KHLFGLRIRV PPVPPNVAFK
       370        380        390        400        410        420
AEKEPEGTSH EFKIKGRKAS KPISDSREVS NGIEKKGKKK SVGRPPGPYT RKMIQKTAEP
       430        440        450        460        470        480
LLDKESISEN PTLDLPCSIG RTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR
       490        500        510        520        530        540
KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE GKEDYQFDEL NTEILNNLAD
       550        560        570        580        590
QELQLNHLKN SITSYFGAAG RIACGEKYRV LARRVTLDGK VQYLVEWEGA TAS         10         20         30         40         50         60
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL
        70         80         90        100        110        120
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV
       130        140        150        160        170        180
ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ
       190        200        210        220        230        240
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF
       250        260        270        280        290        300
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
       310        320        330        340        350        360
DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEIKKK KHLFGLRIRV PPVPPNVAFK
       370        380        390        400        410        420
AEKEPEGTSH EFKIKGRKAS KPISDSREVS NGIEKKGKKK SVGRPPGPYT RKMIQKTAEP
       430        440        450        460        470        480
LLDKESISEN PTLDLPCSIG RTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR
       490        500        510        520        530        540
KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE GKEDYQFDEL NTEILNNLAD
       550        560        570        580        590
QELQLNHLKN SITSYFGAAG RIACGEKYRV LARRVTLDGK VQYLVEWEGA TAS         10         20         30         40         50         60
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL
        70         80         90        100        110        120
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV
       130        140        150        160        170        180
ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ
       190        200        210        220        230        240
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF
       250        260        270        280        290        300
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
       310        320        330        340        350        360
DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEIKKK KHLFGLRIRV PPVPPNVAFK
       370        380        390        400        410        420
AEKEPEGTSH EFKIKGRKAS KPISDSREVS NGIEKKGKKK SVGRPPGPYT RKMIQKTAEP
       430        440        450        460        470        480
LLDKESISEN PTLDLPCSIG RTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR
       490        500        510        520        530        540
KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE GKEDYQFDEL NTEILNNLAD
       550        560        570        580        590
QELQLNHLKN SITSYFGAAG RIACGEKYRV LARRVTLDGK VQYLVEWEGA TAS         10         20         30         40         50         60
MRDSTGAGNS LVHKRSPLRR NQKTPTSLTK LSLQDGHKAK KPACKFEEGQ DVLARWSDGL
        70         80         90        100        110        120
FYLGTIKKIN ILKQSCFIIF EDSSKSWVLW KDIQTGATGS GEMVCTICQE EYSEAPNEMV
       130        140        150        160        170        180
ICDKCGQGYH QLCHTPHIDS SVIDSDEKWL CRQCVFATTT KRGGALKKGP NAKALQVMKQ
       190        200        210        220        230        240
TLPYSVADLE WDAGHKTNVQ QCYCYCGGPG DWYLKMLQCC KCKQWFHEAC VQCLQKPMLF
       250        260        270        280        290        300
GDRFYTFICS VCSSGPEYLK RLPLQWVDIA HLCLYNLSVI HKKKYFDSEL ELMTYINENW
       310        320        330        340        350        360
DRLHPGELAD TPKSERYEHV LEALNDYKTM FMSGKEIKKK KHLFGLRIRV PPVPPNVAFK
       370        380        390        400        410        420
AEKEPEGTSH EFKIKGRKAS KPISDSREVS NGIEKKGKKK SVGRPPGPYT RKMIQKTAEP
       430        440        450        460        470        480
LLDKESISEN PTLDLPCSIG RTEGTAHSSN TSDVDFTGAS SAKETTSSSI SRHYGLSDSR
       490        500        510        520        530        540
KRTRTGRSWP AAIPHLRRRR GRLPRRALQT QNSEIVKDDE GKEDYQFDEL NTEILNNLAD
       550        560        570        580        590
QELQLNHLKN SITSYFGAAG RIACGEKYRV LARRVTLDGK VQYLVEWEGA TAS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y483-1-unknown	MRDSTG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y483-1-unknown	MRDSTG...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81717
Q9Y483-103-unknown	MVCTIC...	103	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81716
Q9Y483-103-unknown	MVCTIC...	103	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98766
Q9Y483-332-unknown	MSGKEI...	332	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81715
Q9Y483-332-unknown	MSGKEI...	332	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt98703
Q9Y483-456-	FTGASS...	456		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
Q9Y483-456-	FTGASS...	456		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9Y483-456-unknown	FTGASS...	456	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168378
Q9Y483-456-unknown	FTGASS...	456	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168377
Q9Y483-456-unknown	FTGASS...	456	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168376

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GATAS	593	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GATAS	593	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77333
...GATAS	593	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77334
...GATAS	593	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt77335

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)