Q9Y4D8: Probable E3 ubiquitin-protein ligase HECTD4
| Protein names | - Probable E3 ubiquitin-protein ligase HECTD4 - 2.3.2.26 - HECT domain-containing protein 4 - HECT-type E3 ubiquitin transferase HECTD4 |
|---|---|
| Gene names | HECTD4 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9Y4D8 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MPANHLPIGS TMSTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDIFEL VVENGVFVAN
70 80 90 100 110 120
PLQERTILMR KEGESAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAANTSC
130 140 150 160 170 180
GLPLKMLRKT PIYTCGTYLV MLVPPPGGSG SSATRSLFGG TSGLSSLKRA CYDTVNNMLW
190 200 210 220 230 240
TCSNDYIDQW CNPGNQAFHY VCQRLGVSHI ITEPKEEAIT TNEVINQLLH HVGAMCIHQL
250 260 270 280 290 300
NLLATNPNLP ITSVLGKQHP IEAHHLSSIC DIMEKAMVNG DTCIIRCILV VFQVVFKFFF
310 320 330 340 350 360
SPQTERNRDI IRRSGLLLWQ LLMAPKDQIC PEIQKEVCLA ISSGLNILYP GETEINNLLK
370 380 390 400 410 420
LVLTEGERNS GLSQLRDVIL TNLAEQLQNN RFGSDEDDHY RLNDELLHYI LKIVVRESCI
430 440 450 460 470 480
LITKCQTVSK DDFQKLLSTV PAASSCLRYL MAVQNHLLSN TILIKPDEND DSDSSLQGET
490 500 510 520 530 540
LKVQELKVSI LALATQILTG CDEVLEMLQQ VTTALINSDI ADREQRLKGL EQVTKATMLG
550 560 570 580 590 600
HLLPVLLTSL MHPNLQTLIM ADALMPQLVQ LVLYTSQTAL LLKTQCPVFA EVGCSPCGAP
610 620 630 640 650 660
DQKCRLFPDE RMLEEKEEPG FLTGLKIPAP WAAGKTVETV HPVRDNYKFK ETVHIPGARC
670 680 690 700 710 720
LYLRFDSRCS SQYDYDKLVI YAGPNTNSRK VAEYGGNTLG YGSRSVLGTG WPKDLVKCIS
730 740 750 760 770 780
PPSLNFKVEG DTVTFSFEMR SGREHNTPDK AMWGFACTVR AQESSEDVSG GLPFLVDLAL
790 800 810 820 830 840
GLSVLACSML RILYNGPEIT KEEEACQELL RSKLLQRCQW QVEANGVISP ALTPSPSPLP
850 860 870 880 890 900
LTIEEDREFT YPSDVLVPPV GNYFDLPRIR LPPGIMIKLR EISGRARPQF RPSIKEVIQP
910 920 930 940 950 960
DVMEEMVVSC VIKHLNLVDA LQSLINFQYQ EEHAEEYDLL CKIMGETFKK LNAMERQLQS
970 980 990 1000 1010 1020
VAELEQKWQS EVDDAMQGKL ENNMPFFYDY HFNENKMKEL ELLCSMKEVS FDGNDLENMV
1030 1040 1050 1060 1070 1080
LSLREKFLQE VNSLIQKPSH PLAKTKTLVK SLMNRAELLL HVTIAAQSGL TRSISGTPAE
1090 1100 1110 1120 1130 1140
TPACKSASET KVISHAVRQP VFLRSMSAPS DLEMIGNEDL EFTRANQRRR HVTSHRSSSF
1150 1160 1170 1180 1190 1200
TLLQSLAIED SRDKPTYSVL LGQLFAFIGT NPDQAVSSSS FLLAAQTRWR RGNTRKQALV
1210 1220 1230 1240 1250 1260
HMRELLTAAV RVGGVTHLVG PVTMVLQGGP RIEELTCGGM VEQVQEAFGE TMTSVVSLCA
1270 1280 1290 1300 1310 1320
RYPIACANSI GLLCTIPYTR SEEKCLVRSG LVQLMDRLCS LSNQTESSSS EKQTKKQKVA
1330 1340 1350 1360 1370 1380
TMAWAAFQVL ANRCVEWEKE EGGSTEAVHS GLARQVSSLL TNHLARATEC CGNQAAGNDA
1390 1400 1410 1420 1430 1440
LQDVLSLLND LSRSHIGKAI LSQPACVSKL LSLLLDQRPS PKLVLIILQL CRAALPLMSV
1450 1460 1470 1480 1490 1500
EDCGNVELPP WSYSVPSLNS EQEDPSDPAS KIASLLLAKL ADYVVPGCQT VLSPTASEPD
1510 1520 1530 1540 1550 1560
TTLTKTSPKN SLKGDKDPGE ESEAVDGKLS IFIHKREDQS SHEVLQPLLS SSEGRPFRLG
1570 1580 1590 1600 1610 1620
TGANMEKVVK MDRDMTKGGC CEVITEEAAA ALRKATKWAQ SGLIVSIGPP VESINPETVS
1630 1640 1650 1660 1670 1680
GLSTGDKKKT AQTSICRERN SELARTDPVR PFISGHVANS MAAEVIALLH SLLMAPESNA
1690 1700 1710 1720 1730 1740
AQIWTTTAEK VLSRALMYIP QLGKYAESIL ENGSSSGRKL AKLQRIARQA VAALCALGGF
1750 1760 1770 1780 1790 1800
KETIKIGSEV QVLGRGISGS IGVVASINEQ EGIATVRFPP IDCRKTSQAS DTLTIPLSRL
1810 1820 1830 1840 1850 1860
CVPRSEALPL HKLSITEKVV QAVQSMLLPQ EGSLSIHTSL PATGDGSAPV MAVVRLLAEI
1870 1880 1890 1900 1910 1920
RTRACLVMAQ LLEDSLFCEE FIQQCPAAVE VLNLVAQECS AGERLAVVEV QCERLRMLYR
1930 1940 1950 1960 1970 1980
DCARPPPPPL QADRRQPKEI TWSPSRVFPP VRACMFSSHL TSVTFLADPS AGGGLPRGTF
1990 2000 2010 2020 2030 2040
IYATSPLPVQ APSFYWEIEI VSYGDTDDDT GPIVSFGFTT EAEKRDGAWT NPVGTCLFHN
2050 2060 2070 2080 2090 2100
NGRAVHYNGS SLLQWKSVRL DVTLSPGDVA GIGWERTEGT PPPPGQPAKG RVYFTYCGQR
2110 2120 2130 2140 2150 2160
LSPYLEDVSG GMWPVVHIQK KNTKTRANFG SRPFAYAEGQ AHRNAADLCT DLAEEISANF
2170 2180 2190 2200 2210 2220
EALPFAMASD SDNDAGTSIA SDPGTHGPPC RIAAVATAQQ QYDSDTSCHY KVELSYENFI
2230 2240 2250 2260 2270 2280
TSGPDPHPPP IADDESDDDD DDDIPQEDHY ALLVKAWETK VFPTIRRRFR NEAERKSGLD
2290 2300 2310 2320 2330 2340
QIKGALQLGM VDIARQTVEF LYEENGGIPR DLYLPTIEDI KDEANKFTID KVRKGLTVVT
2350 2360 2370 2380 2390 2400
RSPDSNNVAS SAVGTALPKF AIRGMLKTFG LHGVVLDVDS VNELVQVETY LRSEGVLVRY
2410 2420 2430 2440 2450 2460
WYPIDMLERP PAGYRRTATN GLVTLDNTNL QIHRELLRCE AALARLYCRM ALLNIFAPKL
2470 2480 2490 2500 2510 2520
PHLFTRLFHI PAIRDITLEH LQLLSNQLLA PPLPDGTISS SSILLAQSLQ HCIHSQNCSA
2530 2540 2550 2560 2570 2580
TDLFYQGNSQ TVREWLNVAI TRTLHQGEES LLELTKQICS FLQTAPEQFP SEEFPISESK
2590 2600 2610 2620 2630 2640
VNMDVNFPGA AFVVVSCKES QSGFRKDSSL YKAPWARVLV YGLGHKVKRN GQLNLIEAAC
2650 2660 2670 2680 2690 2700
YPRDASPANT GLAPPPTADQ YPSVVLSTDR VHIKLGVSPP PGAVLVLHSL PLEFPLAMAF
2710 2720 2730 2740 2750 2760
AEQLLSWKSE DSEGKSEDEP DTIPTSVLLQ VVELLGNFLW TTDMAACVKE LVFHLLAELL
2770 2780 2790 2800 2810 2820
RTVHTLEQRR HPAGLSSSIA LQLNPCLAML MALQSELHKL YDEETQNWVS GGACGGSGGA
2830 2840 2850 2860 2870 2880
AAGDQGRFST YFHALMEGCL AVAEVTLPTN MSVTASGVTS ATAPNLSDSS SSSSSSPGQT
2890 2900 2910 2920 2930 2940
PQSPSLLSKR KKVKMKREKA SSSGKRQSSR TVDSDPTVLS IGGSKPEDML WFHRALTLLI
2950 2960 2970 2980 2990 3000
ILRHLTRKDP QGLGVTSDAI ADACQALVGP TAHSRLLVIS GIPTHLDEGV VRGAIRKACN
3010 3020 3030 3040 3050 3060
AHGGVFKDEI YIPLQEEDTK KPKDKAEGGD GKVEPEKTLA FPGTDSMEVS TSSSLTPAMS
3070 3080 3090 3100 3110 3120
ISASASTSQA SICSSQGISQ TVSDLSVDPL PAGLELPIPP GLLEPHAVSS QESLDISLCS
3130 3140 3150 3160 3170 3180
TGSLGSLGSL GEPLDNAETA SVSDMGSMYT VTSLDNQPLA ARPIKGFAVV EIRSRAKIEK
3190 3200 3210 3220 3230 3240
IRASLFNNND LIGLSSLDGE DELMEMSTEE ILTVSVVNQS LFDTQGSPGL EDYFNDKSIK
3250 3260 3270 3280 3290 3300
GEKLVPGARE VLTEIFKSCA HSEQTLSLTP AKPIRVSDIY LSKEQINSQT PGNLLHLFFT
3310 3320 3330 3340 3350 3360
NVRPPKKVLE DQLTQILRKY GVPKPKFDKS KYSKAGKEQH PVKVVSTKRP ITKPPAKDKA
3370 3380 3390 3400 3410 3420
VLNSVSRTAL SEKKPTVKPK SPEKSKPDEK DPEKSPTKKQ EVPEEKYLTL EGFHKFVIDR
3430 3440 3450 3460 3470 3480
ARQDIRSVWR AILSCGYDLH FERCACIDVR HAQKASRKWT LEMDVALVQY INQLCRHLAI
3490 3500 3510 3520 3530 3540
TPARLHPHEV YLDPADAADP RVACLLNVPI ESLRLRFALL QSLNTTLETF FLPLVELRQT
3550 3560 3570 3580 3590 3600
PMYTHSIAAL LKEAKGLIFY DTKVTVMNRV LNATVQRTAD HAAPEITLDP LEIVGGEIRA
3610 3620 3630 3640 3650 3660
SENSYFCQAA RQLASVPSSQ LCVKLASGGD PTYAFNIRFT GEEVHGTSGS FRHFLWQVCK
3670 3680 3690 3700 3710 3720
ELQSSSLSLL LLCPSSAVNK NKGKYILTPS PITYGEEQLL HFLGQLLGIA IRADVPLPLD
3730 3740 3750 3760 3770 3780
LLPSFWKTLV GEPLDPEQDL QEADILTYNY VKKFESINDE TELEALCAEI ASQHLATESP
3790 3800 3810 3820 3830 3840
DSPNKPCCRF TYLTMTGEEV ELCSRGRHIL VAWENKDIYA AAIRSLRLRE LQNVECVTAV
3850 3860 3870 3880 3890 3900
RAGLGSIIPL QLLTMLSPLE MELRTCGLPY INLEFLKAHT MYQVGLMETD QHIEFFWGAL
3910 3920 3930 3940 3950 3960
EMFTQEELCK FIKFACNQER IPFTCPCKDG GPDTAHVPPY PMKIAPPDGT AGSPDSRYIR
3970 3980 3990
VETCMFMIKL PQYSSLEIML EKLRCAIHYR EDPLSG
Isoforms
- Isoform 2 of Probable E3 ubiquitin-protein ligase HECTD4 - Isoform 3 of Probable E3 ubiquitin-protein ligase HECTD4 - Isoform 4 of Probable E3 ubiquitin-protein ligase HECTD4 - Isoform 5 of Probable E3 ubiquitin-protein ligase HECTD4Sequence View
10 20 30 40 50 60
MPANHLPIGS TMSTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDIFEL VVENGVFVAN
70 80 90 100 110 120
PLQERTILMR KEGESAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAANTSC
130 140 150 160 170 180
GLPLKMLRKT PIYTCGTYLV MLVPPPGGSG SSATRSLFGG TSGLSSLKRA CYDTVNNMLW
190 200 210 220 230 240
TCSNDYIDQW CNPGNQAFHY VCQRLGVSHI ITEPKEEAIT TNEVINQLLH HVGAMCIHQL
250 260 270 280 290 300
NLLATNPNLP ITSVLGKQHP IEAHHLSSIC DIMEKAMVNG DTCIIRCILV VFQVVFKFFF
310 320 330 340 350 360
SPQTERNRDI IRRSGLLLWQ LLMAPKDQIC PEIQKEVCLA ISSGLNILYP GETEINNLLK
370 380 390 400 410 420
LVLTEGERNS GLSQLRDVIL TNLAEQLQNN RFGSDEDDHY RLNDELLHYI LKIVVRESCI
430 440 450 460 470 480
LITKCQTVSK DDFQKLLSTV PAASSCLRYL MAVQNHLLSN TILIKPDEND DSDSSLQGET
490 500 510 520 530 540
LKVQELKVSI LALATQILTG CDEVLEMLQQ VTTALINSDI ADREQRLKGL EQVTKATMLG
550 560 570 580 590 600
HLLPVLLTSL MHPNLQTLIM ADALMPQLVQ LVLYTSQTAL LLKTQCPVFA EVGCSPCGAP
610 620 630 640 650 660
DQKCRLFPDE RMLEEKEEPG FLTGLKIPAP WAAGKTVETV HPVRDNYKFK ETVHIPGARC
670 680 690 700 710 720
LYLRFDSRCS SQYDYDKLVI YAGPNTNSRK VAEYGGNTLG YGSRSVLGTG WPKDLVKCIS
730 740 750 760 770 780
PPSLNFKVEG DTVTFSFEMR SGREHNTPDK AMWGFACTVR AQESSEDVSG GLPFLVDLAL
790 800 810 820 830 840
GLSVLACSML RILYNGPEIT KEEEACQELL RSKLLQRCQW QVEANGVISP ALTPSPSPLP
850 860 870 880 890 900
LTIEEDREFT YPSDVLVPPV GNYFDLPRIR LPPGIMIKLR EISGRARPQF RPSIKEVIQP
910 920 930 940 950 960
DVMEEMVVSC VIKHLNLVDA LQSLINFQYQ EEHAEEYDLL CKIMGETFKK LNAMERQLQS
970 980 990 1000 1010 1020
VAELEQKWQS EVDDAMQGKL ENNMPFFYDY HFNENKMKEL ELLCSMKEVS FDGNDLENMV
1030 1040 1050 1060 1070 1080
LSLREKFLQE VNSLIQKPSH PLAKTKTLVK SLMNRAELLL HVTIAAQSGL TRSISGTPAE
1090 1100 1110 1120 1130 1140
TPACKSASET KVISHAVRQP VFLRSMSAPS DLEMIGNEDL EFTRANQRRR HVTSHRSSSF
1150 1160 1170 1180 1190 1200
TLLQSLAIED SRDKPTYSVL LGQLFAFIGT NPDQAVSSSS FLLAAQTRWR RGNTRKQALV
1210 1220 1230 1240 1250 1260
HMRELLTAAV RVGGVTHLVG PVTMVLQGGP RIEELTCGGM VEQVQEAFGE TMTSVVSLCA
1270 1280 1290 1300 1310 1320
RYPIACANSI GLLCTIPYTR SEEKCLVRSG LVQLMDRLCS LSNQTESSSS EKQTKKQKVA
1330 1340 1350 1360 1370 1380
TMAWAAFQVL ANRCVEWEKE EGGSTEAVHS GLARQVSSLL TNHLARATEC CGNQAAGNDA
1390 1400 1410 1420 1430 1440
LQDVLSLLND LSRSHIGKAI LSQPACVSKL LSLLLDQRPS PKLVLIILQL CRAALPLMSV
1450 1460 1470 1480 1490 1500
EDCGNVELPP WSYSVPSLNS EQEDPSDPAS KIASLLLAKL ADYVVPGCQT VLSPTASEPD
1510 1520 1530 1540 1550 1560
TTLTKTSPKN SLKGDKDPGE ESEAVDGKLS IFIHKREDQS SHEVLQPLLS SSEGRPFRLG
1570 1580 1590 1600 1610 1620
TGANMEKVVK MDRDMTKGGC CEVITEEAAA ALRKATKWAQ SGLIVSIGPP VESINPETVS
1630 1640 1650 1660 1670 1680
GLSTGDKKKT AQTSICRERN SELARTDPVR PFISGHVANS MAAEVIALLH SLLMAPESNA
1690 1700 1710 1720 1730 1740
AQIWTTTAEK VLSRALMYIP QLGKYAESIL ENGSSSGRKL AKLQRIARQA VAALCALGGF
1750 1760 1770 1780 1790 1800
KETIKIGSEV QVLGRGISGS IGVVASINEQ EGIATVRFPP IDCRKTSQAS DTLTIPLSRL
1810 1820 1830 1840 1850 1860
CVPRSEALPL HKLSITEKVV QAVQSMLLPQ EGSLSIHTSL PATGDGSAPV MAVVRLLAEI
1870 1880 1890 1900 1910 1920
RTRACLVMAQ LLEDSLFCEE FIQQCPAAVE VLNLVAQECS AGERLAVVEV QCERLRMLYR
1930 1940 1950 1960 1970 1980
DCARPPPPPL QADRRQPKEI TWSPSRVFPP VRACMFSSHL TSVTFLADPS AGGGLPRGTF
1990 2000 2010 2020 2030 2040
IYATSPLPVQ APSFYWEIEI VSYGDTDDDT GPIVSFGFTT EAEKRDGAWT NPVGTCLFHN
2050 2060 2070 2080 2090 2100
NGRAVHYNGS SLLQWKSVRL DVTLSPGDVA GIGWERTEGT PPPPGQPAKG RVYFTYCGQR
2110 2120 2130 2140 2150 2160
LSPYLEDVSG GMWPVVHIQK KNTKTRANFG SRPFAYAEGQ AHRNAADLCT DLAEEISANF
2170 2180 2190 2200 2210 2220
EALPFAMASD SDNDAGTSIA SDPGTHGPPC RIAAVATAQQ QYDSDTSCHY KVELSYENFI
2230 2240 2250 2260 2270 2280
TSGPDPHPPP IADDESDDDD DDDIPQEDHY ALLVKAWETK VFPTIRRRFR NEAERKSGLD
2290 2300 2310 2320 2330 2340
QIKGALQLGM VDIARQTVEF LYEENGGIPR DLYLPTIEDI KDEANKFTID KVRKGLTVVT
2350 2360 2370 2380 2390 2400
RSPDSNNVAS SAVGTALPKF AIRGMLKTFG LHGVVLDVDS VNELVQVETY LRSEGVLVRY
2410 2420 2430 2440 2450 2460
WYPIDMLERP PAGYRRTATN GLVTLDNTNL QIHRELLRCE AALARLYCRM ALLNIFAPKL
2470 2480 2490 2500 2510 2520
PHLFTRLFHI PAIRDITLEH LQLLSNQLLA PPLPDGTISS SSILLAQSLQ HCIHSQNCSA
2530 2540 2550 2560 2570 2580
TDLFYQGNSQ TVREWLNVAI TRTLHQGEES LLELTKQICS FLQTAPEQFP SEEFPISESK
2590 2600 2610 2620 2630 2640
VNMDVNFPGA AFVVVSCKES QSGFRKDSSL YKAPWARVLV YGLGHKVKRN GQLNLIEAAC
2650 2660 2670 2680 2690 2700
YPRDASPANT GLAPPPTADQ YPSVVLSTDR VHIKLGVSPP PGAVLVLHSL PLEFPLAMAF
2710 2720 2730 2740 2750 2760
AEQLLSWKSE DSEGKSEDEP DTIPTSVLLQ VVELLGNFLW TTDMAACVKE LVFHLLAELL
2770 2780 2790 2800 2810 2820
RTVHTLEQRR HPAGLSSSIA LQLNPCLAML MALQSELHKL YDEETQNWVS GGACGGSGGA
2830 2840 2850 2860 2870 2880
AAGDQGRFST YFHALMEGCL AVAEVTLPTN MSVTASGVTS ATAPNLSDSS SSSSSSPGQT
2890 2900 2910 2920 2930 2940
PQSPSLLSKR KKVKMKREKA SSSGKRQSSR TVDSDPTVLS IGGSKPEDML WFHRALTLLI
2950 2960 2970 2980 2990 3000
ILRHLTRKDP QGLGVTSDAI ADACQALVGP TAHSRLLVIS GIPTHLDEGV VRGAIRKACN
3010 3020 3030 3040 3050 3060
AHGGVFKDEI YIPLQEEDTK KPKDKAEGGD GKVEPEKTLA FPGTDSMEVS TSSSLTPAMS
3070 3080 3090 3100 3110 3120
ISASASTSQA SICSSQGISQ TVSDLSVDPL PAGLELPIPP GLLEPHAVSS QESLDISLCS
3130 3140 3150 3160 3170 3180
TGSLGSLGSL GEPLDNAETA SVSDMGSMYT VTSLDNQPLA ARPIKGFAVV EIRSRAKIEK
3190 3200 3210 3220 3230 3240
IRASLFNNND LIGLSSLDGE DELMEMSTEE ILTVSVVNQS LFDTQGSPGL EDYFNDKSIK
3250 3260 3270 3280 3290 3300
GEKLVPGARE VLTEIFKSCA HSEQTLSLTP AKPIRVSDIY LSKEQINSQT PGNLLHLFFT
3310 3320 3330 3340 3350 3360
NVRPPKKVLE DQLTQILRKY GVPKPKFDKS KYSKAGKEQH PVKVVSTKRP ITKPPAKDKA
3370 3380 3390 3400 3410 3420
VLNSVSRTAL SEKKPTVKPK SPEKSKPDEK DPEKSPTKKQ EVPEEKYLTL EGFHKFVIDR
3430 3440 3450 3460 3470 3480
ARQDIRSVWR AILSCGYDLH FERCACIDVR HAQKASRKWT LEMDVALVQY INQLCRHLAI
3490 3500 3510 3520 3530 3540
TPARLHPHEV YLDPADAADP RVACLLNVPI ESLRLRFALL QSLNTTLETF FLPLVELRQT
3550 3560 3570 3580 3590 3600
PMYTHSIAAL LKEAKGLIFY DTKVTVMNRV LNATVQRTAD HAAPEITLDP LEIVGGEIRA
3610 3620 3630 3640 3650 3660
SENSYFCQAA RQLASVPSSQ LCVKLASGGD PTYAFNIRFT GEEVHGTSGS FRHFLWQVCK
3670 3680 3690 3700 3710 3720
ELQSSSLSLL LLCPSSAVNK NKGKYILTPS PITYGEEQLL HFLGQLLGIA IRADVPLPLD
3730 3740 3750 3760 3770 3780
LLPSFWKTLV GEPLDPEQDL QEADILTYNY VKKFESINDE TELEALCAEI ASQHLATESP
3790 3800 3810 3820 3830 3840
DSPNKPCCRF TYLTMTGEEV ELCSRGRHIL VAWENKDIYA AAIRSLRLRE LQNVECVTAV
3850 3860 3870 3880 3890 3900
RAGLGSIIPL QLLTMLSPLE MELRTCGLPY INLEFLKAHT MYQVGLMETD QHIEFFWGAL
3910 3920 3930 3940 3950 3960
EMFTQEELCK FIKFACNQER IPFTCPCKDG GPDTAHVPPY PMKIAPPDGT AGSPDSRYIR
3970 3980 3990
VETCMFMIKL PQYSSLEIML EKLRCAIHYR EDPLSG
10 20 30 40 50 60
MPANHLPIGS TMSTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDIFEL VVENGVFVAN
70 80 90 100 110 120
PLQERTILMR KEGESAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAANTSC
130 140 150 160 170 180
GLPLKMLRKT PIYTCGTYLV MLVPPPGGSG SSATRSLFGG TSGLSSLKRA CYDTVNNMLW
190 200 210 220 230 240
TCSNDYIDQW CNPGNQAFHY VCQRLGVSHI ITEPKEEAIT TNEVINQLLH HVGAMCIHQL
250 260 270 280 290 300
NLLATNPNLP ITSVLGKQHP IEAHHLSSIC DIMEKAMVNG DTCIIRCILV VFQVVFKFFF
310 320 330 340 350 360
SPQTERNRDI IRRSGLLLWQ LLMAPKDQIC PEIQKEVCLA ISSGLNILYP GETEINNLLK
370 380 390 400 410 420
LVLTEGERNS GLSQLRDVIL TNLAEQLQNN RFGSDEDDHY RLNDELLHYI LKIVVRESCI
430 440 450 460 470 480
LITKCQTVSK DDFQKLLSTV PAASSCLRYL MAVQNHLLSN TILIKPDEND DSDSSLQGET
490 500 510 520 530 540
LKVQELKVSI LALATQILTG CDEVLEMLQQ VTTALINSDI ADREQRLKGL EQVTKATMLG
550 560 570 580 590 600
HLLPVLLTSL MHPNLQTLIM ADALMPQLVQ LVLYTSQTAL LLKTQCPVFA EVGCSPCGAP
610 620 630 640 650 660
DQKCRLFPDE RMLEEKEEPG FLTGLKIPAP WAAGKTVETV HPVRDNYKFK ETVHIPGARC
670 680 690 700 710 720
LYLRFDSRCS SQYDYDKLVI YAGPNTNSRK VAEYGGNTLG YGSRSVLGTG WPKDLVKCIS
730 740 750 760 770 780
PPSLNFKVEG DTVTFSFEMR SGREHNTPDK AMWGFACTVR AQESSEDVSG GLPFLVDLAL
790 800 810 820 830 840
GLSVLACSML RILYNGPEIT KEEEACQELL RSKLLQRCQW QVEANGVISP ALTPSPSPLP
850 860 870 880 890 900
LTIEEDREFT YPSDVLVPPV GNYFDLPRIR LPPGIMIKLR EISGRARPQF RPSIKEVIQP
910 920 930 940 950 960
DVMEEMVVSC VIKHLNLVDA LQSLINFQYQ EEHAEEYDLL CKIMGETFKK LNAMERQLQS
970 980 990 1000 1010 1020
VAELEQKWQS EVDDAMQGKL ENNMPFFYDY HFNENKMKEL ELLCSMKEVS FDGNDLENMV
1030 1040 1050 1060 1070 1080
LSLREKFLQE VNSLIQKPSH PLAKTKTLVK SLMNRAELLL HVTIAAQSGL TRSISGTPAE
1090 1100 1110 1120 1130 1140
TPACKSASET KVISHAVRQP VFLRSMSAPS DLEMIGNEDL EFTRANQRRR HVTSHRSSSF
1150 1160 1170 1180 1190 1200
TLLQSLAIED SRDKPTYSVL LGQLFAFIGT NPDQAVSSSS FLLAAQTRWR RGNTRKQALV
1210 1220 1230 1240 1250 1260
HMRELLTAAV RVGGVTHLVG PVTMVLQGGP RIEELTCGGM VEQVQEAFGE TMTSVVSLCA
1270 1280 1290 1300 1310 1320
RYPIACANSI GLLCTIPYTR SEEKCLVRSG LVQLMDRLCS LSNQTESSSS EKQTKKQKVA
1330 1340 1350 1360 1370 1380
TMAWAAFQVL ANRCVEWEKE EGGSTEAVHS GLARQVSSLL TNHLARATEC CGNQAAGNDA
1390 1400 1410 1420 1430 1440
LQDVLSLLND LSRSHIGKAI LSQPACVSKL LSLLLDQRPS PKLVLIILQL CRAALPLMSV
1450 1460 1470 1480 1490 1500
EDCGNVELPP WSYSVPSLNS EQEDPSDPAS KIASLLLAKL ADYVVPGCQT VLSPTASEPD
1510 1520 1530 1540 1550 1560
TTLTKTSPKN SLKGDKDPGE ESEAVDGKLS IFIHKREDQS SHEVLQPLLS SSEGRPFRLG
1570 1580 1590 1600 1610 1620
TGANMEKVVK MDRDMTKGGC CEVITEEAAA ALRKATKWAQ SGLIVSIGPP VESINPETVS
1630 1640 1650 1660 1670 1680
GLSTGDKKKT AQTSICRERN SELARTDPVR PFISGHVANS MAAEVIALLH SLLMAPESNA
1690 1700 1710 1720 1730 1740
AQIWTTTAEK VLSRALMYIP QLGKYAESIL ENGSSSGRKL AKLQRIARQA VAALCALGGF
1750 1760 1770 1780 1790 1800
KETIKIGSEV QVLGRGISGS IGVVASINEQ EGIATVRFPP IDCRKTSQAS DTLTIPLSRL
1810 1820 1830 1840 1850 1860
CVPRSEALPL HKLSITEKVV QAVQSMLLPQ EGSLSIHTSL PATGDGSAPV MAVVRLLAEI
1870 1880 1890 1900 1910 1920
RTRACLVMAQ LLEDSLFCEE FIQQCPAAVE VLNLVAQECS AGERLAVVEV QCERLRMLYR
1930 1940 1950 1960 1970 1980
DCARPPPPPL QADRRQPKEI TWSPSRVFPP VRACMFSSHL TSVTFLADPS AGGGLPRGTF
1990 2000 2010 2020 2030 2040
IYATSPLPVQ APSFYWEIEI VSYGDTDDDT GPIVSFGFTT EAEKRDGAWT NPVGTCLFHN
2050 2060 2070 2080 2090 2100
NGRAVHYNGS SLLQWKSVRL DVTLSPGDVA GIGWERTEGT PPPPGQPAKG RVYFTYCGQR
2110 2120 2130 2140 2150 2160
LSPYLEDVSG GMWPVVHIQK KNTKTRANFG SRPFAYAEGQ AHRNAADLCT DLAEEISANF
2170 2180 2190 2200 2210 2220
EALPFAMASD SDNDAGTSIA SDPGTHGPPC RIAAVATAQQ QYDSDTSCHY KVELSYENFI
2230 2240 2250 2260 2270 2280
TSGPDPHPPP IADDESDDDD DDDIPQEDHY ALLVKAWETK VFPTIRRRFR NEAERKSGLD
2290 2300 2310 2320 2330 2340
QIKGALQLGM VDIARQTVEF LYEENGGIPR DLYLPTIEDI KDEANKFTID KVRKGLTVVT
2350 2360 2370 2380 2390 2400
RSPDSNNVAS SAVGTALPKF AIRGMLKTFG LHGVVLDVDS VNELVQVETY LRSEGVLVRY
2410 2420 2430 2440 2450 2460
WYPIDMLERP PAGYRRTATN GLVTLDNTNL QIHRELLRCE AALARLYCRM ALLNIFAPKL
2470 2480 2490 2500 2510 2520
PHLFTRLFHI PAIRDITLEH LQLLSNQLLA PPLPDGTISS SSILLAQSLQ HCIHSQNCSA
2530 2540 2550 2560 2570 2580
TDLFYQGNSQ TVREWLNVAI TRTLHQGEES LLELTKQICS FLQTAPEQFP SEEFPISESK
2590 2600 2610 2620 2630 2640
VNMDVNFPGA AFVVVSCKES QSGFRKDSSL YKAPWARVLV YGLGHKVKRN GQLNLIEAAC
2650 2660 2670 2680 2690 2700
YPRDASPANT GLAPPPTADQ YPSVVLSTDR VHIKLGVSPP PGAVLVLHSL PLEFPLAMAF
2710 2720 2730 2740 2750 2760
AEQLLSWKSE DSEGKSEDEP DTIPTSVLLQ VVELLGNFLW TTDMAACVKE LVFHLLAELL
2770 2780 2790 2800 2810 2820
RTVHTLEQRR HPAGLSSSIA LQLNPCLAML MALQSELHKL YDEETQNWVS GGACGGSGGA
2830 2840 2850 2860 2870 2880
AAGDQGRFST YFHALMEGCL AVAEVTLPTN MSVTASGVTS ATAPNLSDSS SSSSSSPGQT
2890 2900 2910 2920 2930 2940
PQSPSLLSKR KKVKMKREKA SSSGKRQSSR TVDSDPTVLS IGGSKPEDML WFHRALTLLI
2950 2960 2970 2980 2990 3000
ILRHLTRKDP QGLGVTSDAI ADACQALVGP TAHSRLLVIS GIPTHLDEGV VRGAIRKACN
3010 3020 3030 3040 3050 3060
AHGGVFKDEI YIPLQEEDTK KPKDKAEGGD GKVEPEKTLA FPGTDSMEVS TSSSLTPAMS
3070 3080 3090 3100 3110 3120
ISASASTSQA SICSSQGISQ TVSDLSVDPL PAGLELPIPP GLLEPHAVSS QESLDISLCS
3130 3140 3150 3160 3170 3180
TGSLGSLGSL GEPLDNAETA SVSDMGSMYT VTSLDNQPLA ARPIKGFAVV EIRSRAKIEK
3190 3200 3210 3220 3230 3240
IRASLFNNND LIGLSSLDGE DELMEMSTEE ILTVSVVNQS LFDTQGSPGL EDYFNDKSIK
3250 3260 3270 3280 3290 3300
GEKLVPGARE VLTEIFKSCA HSEQTLSLTP AKPIRVSDIY LSKEQINSQT PGNLLHLFFT
3310 3320 3330 3340 3350 3360
NVRPPKKVLE DQLTQILRKY GVPKPKFDKS KYSKAGKEQH PVKVVSTKRP ITKPPAKDKA
3370 3380 3390 3400 3410 3420
VLNSVSRTAL SEKKPTVKPK SPEKSKPDEK DPEKSPTKKQ EVPEEKYLTL EGFHKFVIDR
3430 3440 3450 3460 3470 3480
ARQDIRSVWR AILSCGYDLH FERCACIDVR HAQKASRKWT LEMDVALVQY INQLCRHLAI
3490 3500 3510 3520 3530 3540
TPARLHPHEV YLDPADAADP RVACLLNVPI ESLRLRFALL QSLNTTLETF FLPLVELRQT
3550 3560 3570 3580 3590 3600
PMYTHSIAAL LKEAKGLIFY DTKVTVMNRV LNATVQRTAD HAAPEITLDP LEIVGGEIRA
3610 3620 3630 3640 3650 3660
SENSYFCQAA RQLASVPSSQ LCVKLASGGD PTYAFNIRFT GEEVHGTSGS FRHFLWQVCK
3670 3680 3690 3700 3710 3720
ELQSSSLSLL LLCPSSAVNK NKGKYILTPS PITYGEEQLL HFLGQLLGIA IRADVPLPLD
3730 3740 3750 3760 3770 3780
LLPSFWKTLV GEPLDPEQDL QEADILTYNY VKKFESINDE TELEALCAEI ASQHLATESP
3790 3800 3810 3820 3830 3840
DSPNKPCCRF TYLTMTGEEV ELCSRGRHIL VAWENKDIYA AAIRSLRLRE LQNVECVTAV
3850 3860 3870 3880 3890 3900
RAGLGSIIPL QLLTMLSPLE MELRTCGLPY INLEFLKAHT MYQVGLMETD QHIEFFWGAL
3910 3920 3930 3940 3950 3960
EMFTQEELCK FIKFACNQER IPFTCPCKDG GPDTAHVPPY PMKIAPPDGT AGSPDSRYIR
3970 3980 3990
VETCMFMIKL PQYSSLEIML EKLRCAIHYR EDPLSG
10 20 30 40 50 60
MPANHLPIGS TMSTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDIFEL VVENGVFVAN
70 80 90 100 110 120
PLQERTILMR KEGESAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAANTSC
130 140 150 160 170 180
GLPLKMLRKT PIYTCGTYLV MLVPPPGGSG SSATRSLFGG TSGLSSLKRA CYDTVNNMLW
190 200 210 220 230 240
TCSNDYIDQW CNPGNQAFHY VCQRLGVSHI ITEPKEEAIT TNEVINQLLH HVGAMCIHQL
250 260 270 280 290 300
NLLATNPNLP ITSVLGKQHP IEAHHLSSIC DIMEKAMVNG DTCIIRCILV VFQVVFKFFF
310 320 330 340 350 360
SPQTERNRDI IRRSGLLLWQ LLMAPKDQIC PEIQKEVCLA ISSGLNILYP GETEINNLLK
370 380 390 400 410 420
LVLTEGERNS GLSQLRDVIL TNLAEQLQNN RFGSDEDDHY RLNDELLHYI LKIVVRESCI
430 440 450 460 470 480
LITKCQTVSK DDFQKLLSTV PAASSCLRYL MAVQNHLLSN TILIKPDEND DSDSSLQGET
490 500 510 520 530 540
LKVQELKVSI LALATQILTG CDEVLEMLQQ VTTALINSDI ADREQRLKGL EQVTKATMLG
550 560 570 580 590 600
HLLPVLLTSL MHPNLQTLIM ADALMPQLVQ LVLYTSQTAL LLKTQCPVFA EVGCSPCGAP
610 620 630 640 650 660
DQKCRLFPDE RMLEEKEEPG FLTGLKIPAP WAAGKTVETV HPVRDNYKFK ETVHIPGARC
670 680 690 700 710 720
LYLRFDSRCS SQYDYDKLVI YAGPNTNSRK VAEYGGNTLG YGSRSVLGTG WPKDLVKCIS
730 740 750 760 770 780
PPSLNFKVEG DTVTFSFEMR SGREHNTPDK AMWGFACTVR AQESSEDVSG GLPFLVDLAL
790 800 810 820 830 840
GLSVLACSML RILYNGPEIT KEEEACQELL RSKLLQRCQW QVEANGVISP ALTPSPSPLP
850 860 870 880 890 900
LTIEEDREFT YPSDVLVPPV GNYFDLPRIR LPPGIMIKLR EISGRARPQF RPSIKEVIQP
910 920 930 940 950 960
DVMEEMVVSC VIKHLNLVDA LQSLINFQYQ EEHAEEYDLL CKIMGETFKK LNAMERQLQS
970 980 990 1000 1010 1020
VAELEQKWQS EVDDAMQGKL ENNMPFFYDY HFNENKMKEL ELLCSMKEVS FDGNDLENMV
1030 1040 1050 1060 1070 1080
LSLREKFLQE VNSLIQKPSH PLAKTKTLVK SLMNRAELLL HVTIAAQSGL TRSISGTPAE
1090 1100 1110 1120 1130 1140
TPACKSASET KVISHAVRQP VFLRSMSAPS DLEMIGNEDL EFTRANQRRR HVTSHRSSSF
1150 1160 1170 1180 1190 1200
TLLQSLAIED SRDKPTYSVL LGQLFAFIGT NPDQAVSSSS FLLAAQTRWR RGNTRKQALV
1210 1220 1230 1240 1250 1260
HMRELLTAAV RVGGVTHLVG PVTMVLQGGP RIEELTCGGM VEQVQEAFGE TMTSVVSLCA
1270 1280 1290 1300 1310 1320
RYPIACANSI GLLCTIPYTR SEEKCLVRSG LVQLMDRLCS LSNQTESSSS EKQTKKQKVA
1330 1340 1350 1360 1370 1380
TMAWAAFQVL ANRCVEWEKE EGGSTEAVHS GLARQVSSLL TNHLARATEC CGNQAAGNDA
1390 1400 1410 1420 1430 1440
LQDVLSLLND LSRSHIGKAI LSQPACVSKL LSLLLDQRPS PKLVLIILQL CRAALPLMSV
1450 1460 1470 1480 1490 1500
EDCGNVELPP WSYSVPSLNS EQEDPSDPAS KIASLLLAKL ADYVVPGCQT VLSPTASEPD
1510 1520 1530 1540 1550 1560
TTLTKTSPKN SLKGDKDPGE ESEAVDGKLS IFIHKREDQS SHEVLQPLLS SSEGRPFRLG
1570 1580 1590 1600 1610 1620
TGANMEKVVK MDRDMTKGGC CEVITEEAAA ALRKATKWAQ SGLIVSIGPP VESINPETVS
1630 1640 1650 1660 1670 1680
GLSTGDKKKT AQTSICRERN SELARTDPVR PFISGHVANS MAAEVIALLH SLLMAPESNA
1690 1700 1710 1720 1730 1740
AQIWTTTAEK VLSRALMYIP QLGKYAESIL ENGSSSGRKL AKLQRIARQA VAALCALGGF
1750 1760 1770 1780 1790 1800
KETIKIGSEV QVLGRGISGS IGVVASINEQ EGIATVRFPP IDCRKTSQAS DTLTIPLSRL
1810 1820 1830 1840 1850 1860
CVPRSEALPL HKLSITEKVV QAVQSMLLPQ EGSLSIHTSL PATGDGSAPV MAVVRLLAEI
1870 1880 1890 1900 1910 1920
RTRACLVMAQ LLEDSLFCEE FIQQCPAAVE VLNLVAQECS AGERLAVVEV QCERLRMLYR
1930 1940 1950 1960 1970 1980
DCARPPPPPL QADRRQPKEI TWSPSRVFPP VRACMFSSHL TSVTFLADPS AGGGLPRGTF
1990 2000 2010 2020 2030 2040
IYATSPLPVQ APSFYWEIEI VSYGDTDDDT GPIVSFGFTT EAEKRDGAWT NPVGTCLFHN
2050 2060 2070 2080 2090 2100
NGRAVHYNGS SLLQWKSVRL DVTLSPGDVA GIGWERTEGT PPPPGQPAKG RVYFTYCGQR
2110 2120 2130 2140 2150 2160
LSPYLEDVSG GMWPVVHIQK KNTKTRANFG SRPFAYAEGQ AHRNAADLCT DLAEEISANF
2170 2180 2190 2200 2210 2220
EALPFAMASD SDNDAGTSIA SDPGTHGPPC RIAAVATAQQ QYDSDTSCHY KVELSYENFI
2230 2240 2250 2260 2270 2280
TSGPDPHPPP IADDESDDDD DDDIPQEDHY ALLVKAWETK VFPTIRRRFR NEAERKSGLD
2290 2300 2310 2320 2330 2340
QIKGALQLGM VDIARQTVEF LYEENGGIPR DLYLPTIEDI KDEANKFTID KVRKGLTVVT
2350 2360 2370 2380 2390 2400
RSPDSNNVAS SAVGTALPKF AIRGMLKTFG LHGVVLDVDS VNELVQVETY LRSEGVLVRY
2410 2420 2430 2440 2450 2460
WYPIDMLERP PAGYRRTATN GLVTLDNTNL QIHRELLRCE AALARLYCRM ALLNIFAPKL
2470 2480 2490 2500 2510 2520
PHLFTRLFHI PAIRDITLEH LQLLSNQLLA PPLPDGTISS SSILLAQSLQ HCIHSQNCSA
2530 2540 2550 2560 2570 2580
TDLFYQGNSQ TVREWLNVAI TRTLHQGEES LLELTKQICS FLQTAPEQFP SEEFPISESK
2590 2600 2610 2620 2630 2640
VNMDVNFPGA AFVVVSCKES QSGFRKDSSL YKAPWARVLV YGLGHKVKRN GQLNLIEAAC
2650 2660 2670 2680 2690 2700
YPRDASPANT GLAPPPTADQ YPSVVLSTDR VHIKLGVSPP PGAVLVLHSL PLEFPLAMAF
2710 2720 2730 2740 2750 2760
AEQLLSWKSE DSEGKSEDEP DTIPTSVLLQ VVELLGNFLW TTDMAACVKE LVFHLLAELL
2770 2780 2790 2800 2810 2820
RTVHTLEQRR HPAGLSSSIA LQLNPCLAML MALQSELHKL YDEETQNWVS GGACGGSGGA
2830 2840 2850 2860 2870 2880
AAGDQGRFST YFHALMEGCL AVAEVTLPTN MSVTASGVTS ATAPNLSDSS SSSSSSPGQT
2890 2900 2910 2920 2930 2940
PQSPSLLSKR KKVKMKREKA SSSGKRQSSR TVDSDPTVLS IGGSKPEDML WFHRALTLLI
2950 2960 2970 2980 2990 3000
ILRHLTRKDP QGLGVTSDAI ADACQALVGP TAHSRLLVIS GIPTHLDEGV VRGAIRKACN
3010 3020 3030 3040 3050 3060
AHGGVFKDEI YIPLQEEDTK KPKDKAEGGD GKVEPEKTLA FPGTDSMEVS TSSSLTPAMS
3070 3080 3090 3100 3110 3120
ISASASTSQA SICSSQGISQ TVSDLSVDPL PAGLELPIPP GLLEPHAVSS QESLDISLCS
3130 3140 3150 3160 3170 3180
TGSLGSLGSL GEPLDNAETA SVSDMGSMYT VTSLDNQPLA ARPIKGFAVV EIRSRAKIEK
3190 3200 3210 3220 3230 3240
IRASLFNNND LIGLSSLDGE DELMEMSTEE ILTVSVVNQS LFDTQGSPGL EDYFNDKSIK
3250 3260 3270 3280 3290 3300
GEKLVPGARE VLTEIFKSCA HSEQTLSLTP AKPIRVSDIY LSKEQINSQT PGNLLHLFFT
3310 3320 3330 3340 3350 3360
NVRPPKKVLE DQLTQILRKY GVPKPKFDKS KYSKAGKEQH PVKVVSTKRP ITKPPAKDKA
3370 3380 3390 3400 3410 3420
VLNSVSRTAL SEKKPTVKPK SPEKSKPDEK DPEKSPTKKQ EVPEEKYLTL EGFHKFVIDR
3430 3440 3450 3460 3470 3480
ARQDIRSVWR AILSCGYDLH FERCACIDVR HAQKASRKWT LEMDVALVQY INQLCRHLAI
3490 3500 3510 3520 3530 3540
TPARLHPHEV YLDPADAADP RVACLLNVPI ESLRLRFALL QSLNTTLETF FLPLVELRQT
3550 3560 3570 3580 3590 3600
PMYTHSIAAL LKEAKGLIFY DTKVTVMNRV LNATVQRTAD HAAPEITLDP LEIVGGEIRA
3610 3620 3630 3640 3650 3660
SENSYFCQAA RQLASVPSSQ LCVKLASGGD PTYAFNIRFT GEEVHGTSGS FRHFLWQVCK
3670 3680 3690 3700 3710 3720
ELQSSSLSLL LLCPSSAVNK NKGKYILTPS PITYGEEQLL HFLGQLLGIA IRADVPLPLD
3730 3740 3750 3760 3770 3780
LLPSFWKTLV GEPLDPEQDL QEADILTYNY VKKFESINDE TELEALCAEI ASQHLATESP
3790 3800 3810 3820 3830 3840
DSPNKPCCRF TYLTMTGEEV ELCSRGRHIL VAWENKDIYA AAIRSLRLRE LQNVECVTAV
3850 3860 3870 3880 3890 3900
RAGLGSIIPL QLLTMLSPLE MELRTCGLPY INLEFLKAHT MYQVGLMETD QHIEFFWGAL
3910 3920 3930 3940 3950 3960
EMFTQEELCK FIKFACNQER IPFTCPCKDG GPDTAHVPPY PMKIAPPDGT AGSPDSRYIR
3970 3980 3990
VETCMFMIKL PQYSSLEIML EKLRCAIHYR EDPLSG
10 20 30 40 50 60
MPANHLPIGS TMSTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDIFEL VVENGVFVAN
70 80 90 100 110 120
PLQERTILMR KEGESAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAANTSC
130 140 150 160 170 180
GLPLKMLRKT PIYTCGTYLV MLVPPPGGSG SSATRSLFGG TSGLSSLKRA CYDTVNNMLW
190 200 210 220 230 240
TCSNDYIDQW CNPGNQAFHY VCQRLGVSHI ITEPKEEAIT TNEVINQLLH HVGAMCIHQL
250 260 270 280 290 300
NLLATNPNLP ITSVLGKQHP IEAHHLSSIC DIMEKAMVNG DTCIIRCILV VFQVVFKFFF
310 320 330 340 350 360
SPQTERNRDI IRRSGLLLWQ LLMAPKDQIC PEIQKEVCLA ISSGLNILYP GETEINNLLK
370 380 390 400 410 420
LVLTEGERNS GLSQLRDVIL TNLAEQLQNN RFGSDEDDHY RLNDELLHYI LKIVVRESCI
430 440 450 460 470 480
LITKCQTVSK DDFQKLLSTV PAASSCLRYL MAVQNHLLSN TILIKPDEND DSDSSLQGET
490 500 510 520 530 540
LKVQELKVSI LALATQILTG CDEVLEMLQQ VTTALINSDI ADREQRLKGL EQVTKATMLG
550 560 570 580 590 600
HLLPVLLTSL MHPNLQTLIM ADALMPQLVQ LVLYTSQTAL LLKTQCPVFA EVGCSPCGAP
610 620 630 640 650 660
DQKCRLFPDE RMLEEKEEPG FLTGLKIPAP WAAGKTVETV HPVRDNYKFK ETVHIPGARC
670 680 690 700 710 720
LYLRFDSRCS SQYDYDKLVI YAGPNTNSRK VAEYGGNTLG YGSRSVLGTG WPKDLVKCIS
730 740 750 760 770 780
PPSLNFKVEG DTVTFSFEMR SGREHNTPDK AMWGFACTVR AQESSEDVSG GLPFLVDLAL
790 800 810 820 830 840
GLSVLACSML RILYNGPEIT KEEEACQELL RSKLLQRCQW QVEANGVISP ALTPSPSPLP
850 860 870 880 890 900
LTIEEDREFT YPSDVLVPPV GNYFDLPRIR LPPGIMIKLR EISGRARPQF RPSIKEVIQP
910 920 930 940 950 960
DVMEEMVVSC VIKHLNLVDA LQSLINFQYQ EEHAEEYDLL CKIMGETFKK LNAMERQLQS
970 980 990 1000 1010 1020
VAELEQKWQS EVDDAMQGKL ENNMPFFYDY HFNENKMKEL ELLCSMKEVS FDGNDLENMV
1030 1040 1050 1060 1070 1080
LSLREKFLQE VNSLIQKPSH PLAKTKTLVK SLMNRAELLL HVTIAAQSGL TRSISGTPAE
1090 1100 1110 1120 1130 1140
TPACKSASET KVISHAVRQP VFLRSMSAPS DLEMIGNEDL EFTRANQRRR HVTSHRSSSF
1150 1160 1170 1180 1190 1200
TLLQSLAIED SRDKPTYSVL LGQLFAFIGT NPDQAVSSSS FLLAAQTRWR RGNTRKQALV
1210 1220 1230 1240 1250 1260
HMRELLTAAV RVGGVTHLVG PVTMVLQGGP RIEELTCGGM VEQVQEAFGE TMTSVVSLCA
1270 1280 1290 1300 1310 1320
RYPIACANSI GLLCTIPYTR SEEKCLVRSG LVQLMDRLCS LSNQTESSSS EKQTKKQKVA
1330 1340 1350 1360 1370 1380
TMAWAAFQVL ANRCVEWEKE EGGSTEAVHS GLARQVSSLL TNHLARATEC CGNQAAGNDA
1390 1400 1410 1420 1430 1440
LQDVLSLLND LSRSHIGKAI LSQPACVSKL LSLLLDQRPS PKLVLIILQL CRAALPLMSV
1450 1460 1470 1480 1490 1500
EDCGNVELPP WSYSVPSLNS EQEDPSDPAS KIASLLLAKL ADYVVPGCQT VLSPTASEPD
1510 1520 1530 1540 1550 1560
TTLTKTSPKN SLKGDKDPGE ESEAVDGKLS IFIHKREDQS SHEVLQPLLS SSEGRPFRLG
1570 1580 1590 1600 1610 1620
TGANMEKVVK MDRDMTKGGC CEVITEEAAA ALRKATKWAQ SGLIVSIGPP VESINPETVS
1630 1640 1650 1660 1670 1680
GLSTGDKKKT AQTSICRERN SELARTDPVR PFISGHVANS MAAEVIALLH SLLMAPESNA
1690 1700 1710 1720 1730 1740
AQIWTTTAEK VLSRALMYIP QLGKYAESIL ENGSSSGRKL AKLQRIARQA VAALCALGGF
1750 1760 1770 1780 1790 1800
KETIKIGSEV QVLGRGISGS IGVVASINEQ EGIATVRFPP IDCRKTSQAS DTLTIPLSRL
1810 1820 1830 1840 1850 1860
CVPRSEALPL HKLSITEKVV QAVQSMLLPQ EGSLSIHTSL PATGDGSAPV MAVVRLLAEI
1870 1880 1890 1900 1910 1920
RTRACLVMAQ LLEDSLFCEE FIQQCPAAVE VLNLVAQECS AGERLAVVEV QCERLRMLYR
1930 1940 1950 1960 1970 1980
DCARPPPPPL QADRRQPKEI TWSPSRVFPP VRACMFSSHL TSVTFLADPS AGGGLPRGTF
1990 2000 2010 2020 2030 2040
IYATSPLPVQ APSFYWEIEI VSYGDTDDDT GPIVSFGFTT EAEKRDGAWT NPVGTCLFHN
2050 2060 2070 2080 2090 2100
NGRAVHYNGS SLLQWKSVRL DVTLSPGDVA GIGWERTEGT PPPPGQPAKG RVYFTYCGQR
2110 2120 2130 2140 2150 2160
LSPYLEDVSG GMWPVVHIQK KNTKTRANFG SRPFAYAEGQ AHRNAADLCT DLAEEISANF
2170 2180 2190 2200 2210 2220
EALPFAMASD SDNDAGTSIA SDPGTHGPPC RIAAVATAQQ QYDSDTSCHY KVELSYENFI
2230 2240 2250 2260 2270 2280
TSGPDPHPPP IADDESDDDD DDDIPQEDHY ALLVKAWETK VFPTIRRRFR NEAERKSGLD
2290 2300 2310 2320 2330 2340
QIKGALQLGM VDIARQTVEF LYEENGGIPR DLYLPTIEDI KDEANKFTID KVRKGLTVVT
2350 2360 2370 2380 2390 2400
RSPDSNNVAS SAVGTALPKF AIRGMLKTFG LHGVVLDVDS VNELVQVETY LRSEGVLVRY
2410 2420 2430 2440 2450 2460
WYPIDMLERP PAGYRRTATN GLVTLDNTNL QIHRELLRCE AALARLYCRM ALLNIFAPKL
2470 2480 2490 2500 2510 2520
PHLFTRLFHI PAIRDITLEH LQLLSNQLLA PPLPDGTISS SSILLAQSLQ HCIHSQNCSA
2530 2540 2550 2560 2570 2580
TDLFYQGNSQ TVREWLNVAI TRTLHQGEES LLELTKQICS FLQTAPEQFP SEEFPISESK
2590 2600 2610 2620 2630 2640
VNMDVNFPGA AFVVVSCKES QSGFRKDSSL YKAPWARVLV YGLGHKVKRN GQLNLIEAAC
2650 2660 2670 2680 2690 2700
YPRDASPANT GLAPPPTADQ YPSVVLSTDR VHIKLGVSPP PGAVLVLHSL PLEFPLAMAF
2710 2720 2730 2740 2750 2760
AEQLLSWKSE DSEGKSEDEP DTIPTSVLLQ VVELLGNFLW TTDMAACVKE LVFHLLAELL
2770 2780 2790 2800 2810 2820
RTVHTLEQRR HPAGLSSSIA LQLNPCLAML MALQSELHKL YDEETQNWVS GGACGGSGGA
2830 2840 2850 2860 2870 2880
AAGDQGRFST YFHALMEGCL AVAEVTLPTN MSVTASGVTS ATAPNLSDSS SSSSSSPGQT
2890 2900 2910 2920 2930 2940
PQSPSLLSKR KKVKMKREKA SSSGKRQSSR TVDSDPTVLS IGGSKPEDML WFHRALTLLI
2950 2960 2970 2980 2990 3000
ILRHLTRKDP QGLGVTSDAI ADACQALVGP TAHSRLLVIS GIPTHLDEGV VRGAIRKACN
3010 3020 3030 3040 3050 3060
AHGGVFKDEI YIPLQEEDTK KPKDKAEGGD GKVEPEKTLA FPGTDSMEVS TSSSLTPAMS
3070 3080 3090 3100 3110 3120
ISASASTSQA SICSSQGISQ TVSDLSVDPL PAGLELPIPP GLLEPHAVSS QESLDISLCS
3130 3140 3150 3160 3170 3180
TGSLGSLGSL GEPLDNAETA SVSDMGSMYT VTSLDNQPLA ARPIKGFAVV EIRSRAKIEK
3190 3200 3210 3220 3230 3240
IRASLFNNND LIGLSSLDGE DELMEMSTEE ILTVSVVNQS LFDTQGSPGL EDYFNDKSIK
3250 3260 3270 3280 3290 3300
GEKLVPGARE VLTEIFKSCA HSEQTLSLTP AKPIRVSDIY LSKEQINSQT PGNLLHLFFT
3310 3320 3330 3340 3350 3360
NVRPPKKVLE DQLTQILRKY GVPKPKFDKS KYSKAGKEQH PVKVVSTKRP ITKPPAKDKA
3370 3380 3390 3400 3410 3420
VLNSVSRTAL SEKKPTVKPK SPEKSKPDEK DPEKSPTKKQ EVPEEKYLTL EGFHKFVIDR
3430 3440 3450 3460 3470 3480
ARQDIRSVWR AILSCGYDLH FERCACIDVR HAQKASRKWT LEMDVALVQY INQLCRHLAI
3490 3500 3510 3520 3530 3540
TPARLHPHEV YLDPADAADP RVACLLNVPI ESLRLRFALL QSLNTTLETF FLPLVELRQT
3550 3560 3570 3580 3590 3600
PMYTHSIAAL LKEAKGLIFY DTKVTVMNRV LNATVQRTAD HAAPEITLDP LEIVGGEIRA
3610 3620 3630 3640 3650 3660
SENSYFCQAA RQLASVPSSQ LCVKLASGGD PTYAFNIRFT GEEVHGTSGS FRHFLWQVCK
3670 3680 3690 3700 3710 3720
ELQSSSLSLL LLCPSSAVNK NKGKYILTPS PITYGEEQLL HFLGQLLGIA IRADVPLPLD
3730 3740 3750 3760 3770 3780
LLPSFWKTLV GEPLDPEQDL QEADILTYNY VKKFESINDE TELEALCAEI ASQHLATESP
3790 3800 3810 3820 3830 3840
DSPNKPCCRF TYLTMTGEEV ELCSRGRHIL VAWENKDIYA AAIRSLRLRE LQNVECVTAV
3850 3860 3870 3880 3890 3900
RAGLGSIIPL QLLTMLSPLE MELRTCGLPY INLEFLKAHT MYQVGLMETD QHIEFFWGAL
3910 3920 3930 3940 3950 3960
EMFTQEELCK FIKFACNQER IPFTCPCKDG GPDTAHVPPY PMKIAPPDGT AGSPDSRYIR
3970 3980 3990
VETCMFMIKL PQYSSLEIML EKLRCAIHYR EDPLSG
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9Y4D8-1-unknown | MPANHL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9Y4D8-1-unknown | MPANHL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76869 | |||
| Q9Y4D8-1-unknown | MPANHL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76870 | |||
| Q9Y4D8-1-unknown | MPANHL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76871 | |||
| Q9Y4D8-1-unknown | MPANHL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt99743 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...DPLSG | 3996 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...DPLSG | 3996 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72489 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|